Results 371 to 380 of about 82,547 (381)

The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases.

Nature Reviews Cardiology, 2023
S. Toldo, Antonio Abbate
semanticscholar   +1 more source

Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis.

Immunity, 2023
Rui Miao, Cong Jiang, Winston Y. Chang, Haiwei Zhang, Jinsu An, Felicia Ho, Pengcheng Chen, Han Zhang, Caroline Junqueira, Dulguun Amgalan, Felix G Liang, Junbing Zhang, Charles L. Evavold, Iva Hafner-Bratkovič, Zhibin Zhang, Pietro Fontana, S. Xia, Markus Waldeck-Weiermair, Youdong Pan, Thomas Michel, L. Bar-Peled, Hao Wu, Jonathan C. Kagan, R. Kitsis, Peng Zhang, Xing Liu, Judy Lieberman   +26 more
semanticscholar   +1 more source

Fumarate targets pyroptosis

Science, 2020
Immunometabolism A form of inflammatory cell death called pyroptosis depends on the caspase-mediated cleavage of gasdermin D (GSDMD), the fragments of which assemble into permeability pores that then kill the cell. The mechanisms regulating this important cellular process are not yet fully understood. Humphries et al.
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Pyroptosis in health and disease

American Journal of Physiology-Cell Physiology
The field of cell death has witnessed significant advancements since the initial discovery of apoptosis in the 1970s. This review delves into the intricacies of pyroptosis, a more recently identified form of regulated, lytic cell death, and explores the roles of pyroptotic effector molecules, with a strong emphasis on their mechanisms and relevance in
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PYROPTOSIS and THE MECHANISM OF PYROPTOSIS

2023
Hücresel inflamatuar nekrozolarak da bilinen piroptoz, programlanmış hücre ölümünün yeni bir şeklidir. İlkolarak 1992'de Gram negatif bakterilerle enfekte olmuş makrofajlarda tanımlananpiroptozis daha sonra çeşitli bağışıklık hücrelerinde de bildirilmiştir.
Gezer, Arzu, Karadağ Sarı, Ebru
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Mitochondria control pyroptosis [PDF]

Nature Immunology, 2021
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A palmitoylation-depalmitoylation relay spatiotemporally controls GSDMD activation in pyroptosis.

Nature Cell Biology
Na Zhang, Jian Zhang, Yuanxin Yang, Hengyue Shan, Shouqiao Hou, Hongwen Fang, Min Ma, Zhongwen Chen, Li Tan, Daichao Xu   +9 more
semanticscholar   +1 more source

Full-length GSDME mediates pyroptosis independent from cleavage.

Nature Cell Biology
Bo Zhou, Zhi-Hong Jiang, Meng-Ran Dai, Yuan-Li Ai, Li Xiao, Chuan-Qi Zhong, Liu-zheng Wu, Qi-tao Chen, Hang-zi Chen, Qiao Wu   +9 more
semanticscholar   +1 more source

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death.

TIBS -Trends in Biochemical Sciences. Regular ed, 2017
Jianjin Shi, Wenqing Gao, F. Shao
semanticscholar   +1 more source

Pyroptosis

2014
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