Investigating the metabolic and genetic regulation of ageing using forward genetics screens [PDF]
Metabolic state, protein biogenesis, and the tuning of stress response pathways become dysregulated with ageing and their modification can prolong survival. Their coordinated interaction, however, remains poorly understood.
Mayr, Felix
core
Interaction of 4-Aminobutyrate (GABA) with the Tricarboxylic Acid Cycle in Plants Under Salinity Stress. [PDF]
Flaherty EJ, Shelp BJ.
europepmc +1 more source
Expression and kinetic characterization of PYCR3. [PDF]
Meeks KR, Tanner JJ.
europepmc +1 more source
Mechanism of SMYD2 promoting stemness maintenance of bladder cancer stem cells by regulating PYCR1 expression and PINK1/Parkin mitophagy pathway. [PDF]
Chen J, Xiao S, Yan X, Wei Y, Song W.
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Integrating virtual screening and molecular dynamics simulations to identify emodin as a PYCR1 inhibitor modulating docetaxel sensitivity in prostate cancer. [PDF]
Liu S +12 more
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Glutamine metabolism reprogramming promotes bladder cancer progression via PYCR1: a multi-omics and functional validation study. [PDF]
Ding X +7 more
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Engineered C-N Lyases for Stereoselective Synthesis of Tertiary Amines. [PDF]
Bothof L +4 more
europepmc +1 more source
Structural Features Governing the Metabolic Stability of Tetraethyl-Substituted Nitroxides in Rat Liver Microsomes. [PDF]
Rančić A, Babić N, Orio M, Peyrot F.
europepmc +1 more source
Hypoxia-induced PYCR1 regulates glycolysis and histone lactylation to promote bladder cancer progression and metastasis via SLC6A14/Glutamine metabolism. [PDF]
Li Z, Jiang Q, Yang Q, Zhou Y, Wang J.
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Pyrroline-5-carboxylate Reductase of Neurospora crassa: Partial Purification and Some Properties
T, YURA, H J, VOGEL
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