Results 131 to 140 of about 1,126 (165)

Tanshinone IIA alleviates pulmonary fibrosis by modulating glutamine metabolic reprogramming based on [U-¹³C₅]-glutamine metabolic flux analysis. [PDF]

J Adv Res
Shan B, Guo C, Zhou H, Chen J.
europepmc   +1 more source

Genomic analysis of a novel isolate Vreelandella Titanicae sp. Zn11_249 from the chaotropic environment Salar de Uyuni (Bolivia). [PDF]

BMC Genomics
Sabroso E, Abrusci C, Rodríguez N, Amils R, Martínez JM.   +4 more
europepmc   +1 more source

Homeostatic regulation of NAD(H) and NADP(H) in cells. [PDF]

Genes Dis
Chen L, Xing X, Zhang P, Chen L, Pei H.
europepmc   +1 more source

ヒ酸ストレス下のタバコ培養細胞におけるプロリンの役割 [PDF]

, 2017
MST. NUR-E-NAZMUN NAHAR,
core  

The Effects of swnN Gene Function of Endophytic Fungus Alternaria oxytropis OW 7.8 on Its Swainsonine Biosynthesis. [PDF]

Int J Mol Sci
Liu C, Ding N, Lu P, Yuan B, Li Y, Jiang K.   +5 more
europepmc   +1 more source

Disease variants of human Δ1-pyrroline-5-carboxylate reductase 2 (PYCR2)

Archives of Biochemistry and Biophysics, 2021
Pyrroline-5-carboxylate reductase (PYCR in humans) catalyzes the final step of l-proline biosynthesis by catalyzing the reduction of L-Δ1-pyrroline-5-carboxylate (L-P5C) to l-proline using NAD(P)H as the hydride donor. In humans, three isoforms PYCR1, PYCR2, and PYCR3 are known.
Sagar M. Patel, Javier Seravalli, Xinwen Liang, John J. Tanner, Donald F. Becker   +4 more
openaire   +2 more sources

Crystal Structure of Human Pyrroline-5-carboxylate Reductase

Journal of Molecular Biology, 2006
Pyrroline-5-carboxylate reductase (P5CR) is a universal housekeeping enzyme that catalyzes the reduction of Delta(1)-pyrroline-5-carboxylate (P5C) to proline using NAD(P)H as the cofactor. The enzymatic cycle between P5C and proline is very important for the regulation of amino acid metabolism, intracellular redox potential, and apoptosis.
Zhaohui, Meng, Zhiyong, Lou, Zhe, Liu, Ming, Li, Xiaodong, Zhao, Mark, Bartlam, Zihe, Rao   +6 more
openaire   +2 more sources

Pyrroline-5-carboxylate reductase from Cucurbita cotyledons

Phytochemistry, 1973
Pyrroline-5-carboxylate reductase, which required reduced pyridine nucleotide and Δ′-pyrroline-5-carboxylate for proline synthesis, was isolated from pumpkin cotyledons. The enzyme was found in the soluble fraction and had a 4.5-fold greater activity with NADH than NADPH. The enzyme was inhibited by NH2OH, NADP, ATP and slightly by proline. Glutathione
Shirley A. Splittstoesser, Walter E. Splittstoesser   +1 more
openaire   +1 more source

A radioisotopic assay for Δ1-pyrroline-5-carboxylate reductase

Analytical Biochemistry, 1973
Abstract We describe a radioisotopic assay for Δ 1 -pyrroline-5-carboxylate reductase. In this assay we use Δ 1 -pyrroline-5-carboxylate[U- 14 C] and isolate product l -[U- 14 C]proline by cation-exchange column chromatography.
J M, Phang, S J, Downing, D, Valle
openaire   +2 more sources