Results 81 to 90 of about 1,126 (165)

Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network [PDF]

, 2017
Metabolic diseases and comorbidities represent an ever-growing epidemic where multiple cell types impact tissue homeostasis. Here, the link between the metabolic and gene regulatory networks was studied through experimental and computational analysis ...
Berninger, Philipp, Galhardo, Mafalda, Heinäniemi, Merja, Lin, Jake, Sauter, Thomas, Sinkkonen, Lasse   +5 more
core  

Biocatalytic Synthesis of Homochiral 2-Hydroxy-4-butyrolactone Derivatives by Tandem Aldol Addition and Carbonyl Reduction. [PDF]

ACS Catal, 2023
Moreno CJ, Hernández K, Gittings S, Bolte M, Joglar J, Bujons J, Parella T, Clapés P.   +7 more
europepmc   +1 more source

The Substrate Versatility of Δ¹-Pyrroline-5-carboxylate Reductase (ProC) from <i>Escherichia coli</i>. [PDF]

Molecules
Polverini E, Vecchi A, Capra G, Pastori A, Peracchi A.   +4 more
europepmc   +1 more source

GENETIC ALTERATION OF PYRROLINE-5-CARBOXYLATE REDUCTASE IN NEUROSPORA CRASSA [PDF]

Proceedings of the National Academy of Sciences, 1959
openaire   +2 more sources

Correcting the record – cofactor binding of human pyrroline-5-carboxylate reductase [PDF]

Acta Crystallographica Section A Foundations and Advances, 2017
Kurt L. Krause, Emily M. Christensen, Sagar M. Patel, David A. Korasick, Ashley C. Campbell, Donald F. Becker, John J. Tanner   +6 more
openaire   +1 more source

Functional Impact of a Cancer-Related Variant in Human Δ¹-Pyrroline-5-Carboxylate Reductase 1. [PDF]

ACS Omega, 2023
Daudu OI, Meeks KR, Zhang L, Seravalli J, Tanner JJ, Becker DF.   +5 more
europepmc   +1 more source

Oxidoreductase-Catalyzed Synthesis of Chiral Amines

, 2018
Chiral amines are valuable constituents of many important pharmaceutical compounds and their intermediates. It is estimated that nearly 40-45% small molecule pharmaceuticals contain chiral amine scaffolds in their structures.
Bommarius, Andreas, Grogan, Gideon James, Patil, Mahesh, Yun, Hyungdon   +3 more
core   +1 more source

The key enzyme PYCR1 in proline metabolism: a dual driver of cancer progression and fibrotic remodeling. [PDF]

J Enzyme Inhib Med Chem
Guo P, Wu C, Wang T, Song Y, Liu X, Wang X, Zhu Y, Song B, Zhu Y, Zhang J, Guo L, Tao R, Yu Z, Song B.   +13 more
europepmc   +1 more source

The aldehyde dehydrogenase superfamilies: correlations and deviations in structure and function. [PDF]

Appl Microbiol Biotechnol
Heider J, Hege D.
europepmc   +1 more source

Comparative transcriptome profiling analyses during the lag phase uncover YAP1, PDR1, PDR3, RPN4, and HSF1 as key regulatory genes in genomic adaptation to the lignocellulose derived inhibitor HMF for Saccharomyces cerevisiae [PDF]

, 2010
Menggen Ma, Z Lewis Liu
core   +1 more source