Results 261 to 270 of about 145,153 (320)

Clinical Studies of a Patient With Pyruvate Decarboxylase Deficiency

Archives of Neurology, 1971
A boy with a hereditary defect of pyruvate decarboxylase has had intermittent ataxia, often with choreoathetosis, following fever or excitement, and lasting several days, but is clinically normal between attacks. There were excessive lipid droplets in his skeletal muscle.
W. King Engel, R. A. Pieter Kark, John P. Blass   +2 more
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Kinetic aspects of regulation of pyruvic decarboxylase

Phytochemistry, 1976
Abstract The decarboxylation of pyruvate catalysed by pyruvic decarboxylase (EC 4.1.1.1) from wheat germ is shown to be autocatalytic. Evidence is presented which suggests that the enzyme exists in an active and an inactive form—the latter being converted into the active form in the presence of pyruvate and by low pH.
P. Kenworthy, David D. Davies
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Heterologous expression of pyruvate decarboxylase in Geobacillus thermoglucosidasius

Biotechnology Letters, 2008
Expression of a pyruvate decarboxylase (Pdc) pathway in metabolically versatile thermophilic bacteria could create novel ethanologenic organisms, but no suitable thermostable Pdc is available. We have demonstrated that Pdc from Zymomonas mobilis can be expressed in an active form in Geobacillus thermoglucosidasius at up to 52 degrees C, while ...
David J. Leak, Edward M. Green, Thompson Ann, David J. Studholme, David J. Studholme   +4 more
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Fusion of pyruvate decarboxylase and alcohol dehydrogenase increases ethanol production in Escherichia coli.

ACS Synthetic Biology, 2014
Ethanol is an important biofuel. Heterologous expression of Zymomonas mobilis pyruvate decarboxylase (Pdc) and alcohol dehydrogenase (AdhB) increases ethanol production in Escherichia coli. A fusion of PDC and ADH was generated and expressed in E.
A. Lewicka, Jan J. Lyczakowski, Gavin Blackhurst, Christiana Pashkuleva, Kyle R. Rothschild-Mancinelli, Dainius Tautvaišas, Harry Thornton, Hugo Villanueva, Weike Xiao, Justinas Šlikas, L. Horsfall, A. Elfick, C. French   +12 more
semanticscholar   +1 more source

Characterization of pyruvate decarboxylase genes from rice

Plant Molecular Biology, 1996
The pdc1 gene encoding pyruvate decarboxylase has been isolated and sequenced from an IR54 rice genomic library. In contrast to a previously isolated intron-less rice genomic pdc, pRgpdc3, this gene contains five intervening introns in the coding region and corresponds to a cDNA clone, pRcpdc1, isolated from an IR54-cDNA library constructed from ...
M. Anwar Hossain, M. Anwar Hossain, W. James Peacock, Elizabeth S. Dennis, Thomas K. Hodges, Enamul Huq, Anil Grover, Anil Grover   +7 more
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Activity stain for pyruvate decarboxylase in polyacrylamide gels

Analytical Biochemistry, 1983
A method for the localization of pyruvate decarboxylase bands in polyacrylamide gels after electrophoresis using 1,2-dianilinoethane in dilute acetic acid as reagent for acetaldehyde formed from pyruvate by the holoenzyme is described. A white condensation product forms in the bands and precipitates within a few minutes.
Dorothea Trescher, Hartmut Zehender, Johannes Ullrich   +2 more
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The Interaction of Granaticin with Nucleic Acids and Pyruvate Decarboxylase

Journal of Pharmaceutical Sciences, 1982
The interaction of granaticin with two different yeast ribonucleic acids, dialyzed transfer RNA and calf thymus DNA was studied. Contrary to previous reports, no binding of granaticin to DNA or RNA was observed. The visible spectrum of granaticin on direct mixing or equilibrium dialysis of granaticin with RNA or DNA was unchanged.
Gail Gibson-Clay, Peter Heinstein, Stephen R. Byrn   +2 more
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STUDIES ON PYRUVATE CARBOXYLASE, PYRUVATE DECARBOXYLASE AND LIPOAMIDE DEHYDROGENASE IN SUBACUTE NECROTIZING ENCEPHALOMYELOPATHY [PDF]

Acta Paediatrica, 1982
ABSTRACT. In two autopsy‐proven cases of subacute necrotizing encephalomyelopathy (SNE, Leigh's Disease) the activities of pyruvate carboxylase, pyruvate decarboxylase and lipoamide dehydrogenase were investigated in cultured fibroblasts. Normal activities of pyruvate carboxylase and lipoamide dehydrogenase were found in both cases.
T. L. Hansen, Niels Jacob Brandt, Ernst Christensen   +2 more
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Study of Fluorescence Decay of Pyruvate Decarboxylase

1993
We have studied the fluorescence decay kinetics of apo- and holopyruvate decarboxylase from brewer’s yeast (APDC and HPDC respectively) in the native state as well as after the denaturation by 6 M urea and heating of the solution up to 40° C.
A. A. Maskevich, I. P. Chernikevich
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Induction of Rhizopus oryzae Pyruvate Decarboxylase Genes

Current Microbiology, 2003
Two pyruvate decarboxylase genes, pdcA, and pdcB, were cloned from Rhizopus oryzae. These genes are similar to each other with approximately 85% nucleotide sequence identity within the coding region. Multiple transcriptional start sites and polyadenylation sites were found for both genes.
openaire   +3 more sources