Results 111 to 120 of about 21,656 (280)

Quantitative model for $^{13}$C tracing applied to citrate production and secretion of prostate epithelial tissue [PDF]

open access: yesarXiv, 2019
Healthy human prostate epithelial cells have the unique ability to produce and secrete large amounts of citrate into the lumen of the prostate. Citrate is a Krebs cycle metabolite produced in the condensation reaction between acetyl-CoA and oxaloacetate in the mitochondria of the cell. With the application of $^{13}$C enriched substrates, such as $^{13}
arxiv  

Saccharomyces cerevisiae in the production of fermented beverages [PDF]

open access: yes, 2016
Alcoholic beverages are produced following the fermentation of sugars by yeasts, mainly (but not exclusively) strains of the species, Saccharomyces cerevisiae.
Stewart, Graham G., Walker, Graeme M.
core   +4 more sources

Nuclear Magnetic Resonance Approaches in the Study of 2-Oxo Acid Dehydrogenase Multienzyme Complexes—A Literature Review

open access: yesMolecules, 2013
The 2-oxoacid dehydrogenase complexes (ODHc) consist of multiple copies of three enzyme components: E1, a 2-oxoacid decarboxylase; E2, dihydrolipoyl acyl-transferase; and E3, dihydrolipoyl dehydrogenase, that together catalyze the oxidative ...
Mulchand S. Patel   +2 more
doaj   +1 more source

Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning

open access: yesThe FASEB Journal, Volume 39, Issue 12, 30 June 2025.
Cyanide is coined “the classic metabolic poison”; however, FDA‐approved cyanide chelators do not counteract cyanide's metabolic damage. Here, we review the mechanisms of cyanide toxicity, with a focus on intermediary metabolism. We present the theory that, within the innate plasticity of the metabolome, there may reside metabolic pathways that can ...
Vik S. Bebarta, Anjali K. Nath
wiley   +1 more source

Free Energy of Activation for the Comorosan Effect [PDF]

open access: yesarXiv, 2007
Initial reaction rate data for lactic dehydrogenase / pyruvate, lactic dehydrogenase / lactate and malic dehydrogenase / malate enzyme reactions were analyzed to obtain activation free energy changes of -329, -195 and -221 cal/mole, respectively, for rate increases associated with time-specific irradiation of the crystalline substrates prior to ...
arxiv  

Electron transport phosphorylation in rumen butyrivibrios: unprecedented ATP yield for glucose fermentation to butyrate. [PDF]

open access: yes, 2015
From a genomic analysis of rumen butyrivibrios (Butyrivibrio and Pseudobutyrivibrio sp.), we have re-evaluated the contribution of electron transport phosphorylation (ETP) to ATP formation in this group.
Firkins, Jeffrey L, Hackmann, Timothy J
core   +2 more sources

Stopped-Flow Spectrophotometric Study of the Kinetics and Mechanism of CO2 Uptake by cis-[Cr(C2O4)(BaraNH2)(OH2)2]+ Cation and the Acid-Catalyzed Decomposition of cis-[Cr(C2O4)(BaraNH2)OCO2]− Anion in Aqueous Solution

open access: yesMolecules, 2011
The kinetics of CO2 uptake by the cis-[Cr(C2O4)(BaraNH2)(OH2)2]+ complex cation and the acid hydrolysis of the cis-[Cr(C2O4)(BaraNH2)OCO2]− complex anion (where BaraNH2 denotes methyl 3-amino-2,3-dideoxy-b-D-arabino-hexopyranoside) were studied using the
Lech Chmurzyński   +2 more
doaj   +1 more source

Affinity‐Based Protein Profiling Reveals IDH2 as a Mitochondrial Target of Cannabinol in Receptor‐Independent Neuroprotection

open access: yesChemistry – A European Journal, Volume 31, Issue 33, June 12, 2025.
A chemical probe CBN‐P based on the neuroprotective cannabinoid cannabinol (CBN) was developed and synthesized. CNB‐P was found to have a similar mechanism of action as the parent compound and was used in click‐CLEM microscopy studies and affinity‐based protein profiling to identify the mitochondrial protein isocitrate dehydrogenase 2 (IDH2) as one ...
Eva Schaller   +5 more
wiley   +1 more source

Dependence of Substrate Irradiation Reaction Rate Stimulation on Lactic Dehydrogenase Source [PDF]

open access: yesarXiv, 2013
Stimulation of LDH initial reaction rates by timed pre-irradiation of crystalline sodium pyruvate and lithium lactate is reported for enzymes isolated from rabbit muscle, pig heart, human erythrocytes and chicken heart. The phenomenon investigated is referred to as the Comorosan effect.
arxiv  

An Adaptation To Life In Acid Through A Novel Mevalonate Pathway. [PDF]

open access: yes, 2016
Extreme acidophiles are capable of growth at pH values near zero. Sustaining life in acidic environments requires extensive adaptations of membranes, proton pumps, and DNA repair mechanisms.
Bowie, James U   +3 more
core   +1 more source

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