Results 141 to 150 of about 11,092 (201)
Some of the next articles are maybe not open access.
Decarboxylation and carboxylation of pyruvate in the living mice
Biochimie, 1979Mice received intravenously [1- or 2-14C]acetate, [1-, 2- or 3-14C] or [2-14C]pyruvate and were killed 1, 3, 5 or 15 min later. The radioactivity of CO2 or HCO3- of liver or carcass as well as the radioactivity of blood glucose were measured. The ratio of the radioactivity found in these compounds after [3-14C] or [2-14C-A1pyruvate injection suggests ...
P. Favarger, Sylvette Bas, Simonne Rous
openaire +3 more sources
Attempts to inhibit ruminal methanogenesis by blocking pyruvate oxidative decarboxylation
Canadian Journal of Microbiology, 2003 The inhibition of pyruvate oxidative decarboxylation as a means of decreasing ruminal methanogenesis in vitro was studied. In the first experiment, the addition of adenosine and adenine (with and without ribose) to ruminal batch cultures did not decrease methanogenesis. In the second experiment, the addition of oxythiamin decreased methanogenesis by 23%
Emilio M. Ungerfeld +2 more
openalex +4 more sources
Estimation of pyruvate decarboxylation in perfused rat skeletal muscle
Biochemical and Biophysical Research Communications, 1983By the determination of pyruvate dehydrogenase activity in tissue homogenates only limited information is gained on the actual metabolic flux. We therefore determined pyruvate decarboxylation in isolated rat hindlimbs non recirculating perfused with physiological (1-14C)pyruvate levels.
Peter Schadewaldt +3 more
openaire +3 more sources
Decarboxylation of pyruvic acid in aqueous solution by thermal proteinoids
Archives of Biochemistry and Biophysics, 1968Abstract Thermal proteinoids accelerate the conversion of pyruvic acid to carbon dioxide and acetic acid. The reaction follows Michaelis-Menten kinetics. Co-poly(glutamic acid-threonine) and co-poly (glutamic acid-leucine) were found to be the most active of simple co-polymers and even more active than proteinoid.
Heinrich G. Hardebeck +2 more
openaire +3 more sources
A DFT study of the structures of pyruvic acid isomers and their decarboxylation
Organic & Biomolecular Chemistry, 2006Pyruvic acid and its isomers, including the enol tautomers and enantiomeric lactone structures, have been investigated at the B3LYP/6-311 + + G(3df,3pd) level, and it is found that a keto form with trans C(methyl)C(keto)C(acid)O(hydroxyl) and cis C(keto)C(acid)OH, and with one methyl hydrogen in a synperiplanar position with respect to the keto oxygen,
Mallika Pathak +2 more
openaire +3 more sources
Impaired oxidative decarboxylation of pyruvate in fibroblasts from patients with Parkinson's disease
Journal of Neural Transmission - Parkinson's Disease and Dementia Section, 1994 Whether or not a reported deficiency in brain mitochondrial complex I activity in Parkinson's disease represents a defect encompassing other organs or tissues has been a source of some controversy. We have examined mitochondrial respiration in fibroblasts from patients with Parkinson's disease by measuring the oxidative decarboxylation of [2-14C ...
Catherine Mytilineou +5 more
openalex +4 more sources
A thiamin-utilizing ribozyme decarboxylates a pyruvate-like substrate
Nature Chemistry, 2013Vitamins are hypothesized to be relics of an RNA world, and were probably participants in RNA-mediated primordial metabolism. If catalytic RNAs, or ribozymes, could harness vitamin cofactors to aid their function in a manner similar to protein enzymes, it would enable them to catalyse a much larger set of chemical reactions.
Dipankar Sen, Paul Cernak
openaire +3 more sources
Pyruvate Decarboxylase: A Molecular Modeling Study of Pyruvate Decarboxylation and Acyloin Formation
Journal of the American Chemical Society, 1996Using crystal structure data for the pyruvate decarboxylase from Saccharomyces uvarum (which is nearly identical with the enzyme from Saccharomyces cerevisiae), molecular modeling studies have been carried out to investigate the mode of action of the enzyme. Each step of the decarboxylation mechanism can be explained by assuming that the 4‘-amino group
David H. G. Crout, Mario Lobell
openaire +2 more sources
Noradrenaline effects on pyruvate decarboxylation: Correlation with calcium signaling
Journal of Neuroscience Research, 1999Noradrenaline effects on the rate of metabolism of pyruvate to acetyl coenzyme A, catalyzed by the pyruvate dehydrogenase complex, was measured in primary cultures of mouse astrocytes as rate of production of labeled CO(2) from 1-[(14) C]pyruvate in the absence of competing glucose in the medium.
Ye Chen, Leif Hertz
openaire +2 more sources