Results 31 to 40 of about 11,092 (201)

Cis-[Cr(C2O4)(pm)(OH2)2]+ Coordination Ion as a Specific Sensing Ion for H2O2 Detection in HT22 Cells

Molecules, 2014
The purpose of this study was to examine the application of the coordinated cis-[Cr(C2O4)(pm)(OH)2]+ cation where pm denotes pyridoxamine, as a specific sensing ion for the detection of hydrogen peroxide (H2O2).
Dagmara Jacewicz, Kamila Siedlecka-Kroplewska, Joanna Pranczk, Dariusz Wyrzykowski, Michał Woźniak, Lech Chmurzyński   +5 more
doaj   +1 more source

Regulation of pyruvate dehydrogenase complex related to lactate switch in CHO cells

Engineering in Life Sciences, 2021
The metabolism of Chinese hamster ovary (CHO) cell lines is typically characterized by high rates of aerobic glycolysis with increased lactate formation, known as the ”Warburg” effect.
Johannes Möller, Krathika Bhat, Lotta Guhl, Ralf Pörtner, Uwe Jandt, An‐Ping Zeng   +5 more
doaj   +1 more source

Metabolic fate of the carboxyl groups of malate and pyruvate and their influence on δ13C of leaf respired CO2 during light enhanced dark respiration

Frontiers in Plant Science, 2016
The enhanced CO2 release of illuminated leaves transferred into darkness, termed light enhanced dark respiration (LEDR), is often associated with an increase in the carbon isotope ratio of the respired CO2 (δ13CLEDR). The latter has been hypothesized to
Marco M Lehmann, Marco M Lehmann, Frederik eWegener, Matti eBarthel, Veronica Graciela Maurino, Rolf T.W. Siegwolf, Nina eBuchmann, Christiane eWerner, Roland A Werner   +8 more
doaj   +1 more source

Diversity of ThDP-Dependent Enzymes Forming Chiral Tertiary Alcohols. [PDF]

Chembiochem
Chiral tertiary alcohols are widespread in nature and bioactive compounds; however, their asymmetric synthesis faces several challenges. This review outlines the toolbox of ThDP‐dependent enzymes able to produce tertiary alcohols through the formation of CC bond formation using ketones as acceptor substrates. Herein, the substrate scope, the diversity
Bjarnesen D, Lanza L, Presini F, Giovannini PP, Müller M.   +4 more
europepmc   +2 more sources

Dichloroacetate, the Pyruvate Dehydrogenase Complex and the Modulation of mESC Pluripotency. [PDF]

PLoS ONE, 2015
The pyruvate dehydrogenase (PDH) complex is localized in the mitochondrial matrix catalyzing the irreversible decarboxylation of pyruvate to acetyl-CoA and NADH.
Ana Sofia Rodrigues, Marcelo Correia, Andreia Gomes, Sandro L Pereira, Tânia Perestrelo, Maria Inês Sousa, João Ramalho-Santos   +6 more
doaj   +1 more source

Thirdhand cigarette smoke leads to age‐dependent and persistent alterations in the cecal microbiome of mice

MicrobiologyOpen, 2021
The gut microbiome composition is influenced by many factors including environmental exposures. Here, we investigated the effect of thirdhand cigarette smoke (THS) and exposure age on gut microbiome diversity.
Li He, Yan‐Xia Zhou, Yuqing Zhang, Bo Hang, Hang Chang, Suzaynn F. Schick, Susan E. Celniker, Yankai Xia, Antoine M. Snijders, Jian‐Hua Mao   +9 more
doaj   +1 more source

Pyruvate dehydrogenase complex deficiency: updating the clinical, metabolic and mutational landscapes in a cohort of Portuguese patients

Orphanet Journal of Rare Diseases, 2020
Background The pyruvate dehydrogenase complex (PDC) catalyzes the irreversible decarboxylation of pyruvate into acetyl-CoA. PDC deficiency can be caused by alterations in any of the genes encoding its several subunits.
Hana Pavlu-Pereira, Maria João Silva, Cristina Florindo, Sílvia Sequeira, Ana Cristina Ferreira, Sofia Duarte, Ana Luísa Rodrigues, Patrícia Janeiro, Anabela Oliveira, Daniel Gomes, Anabela Bandeira, Esmeralda Martins, Roseli Gomes, Sérgia Soares, Isabel Tavares de Almeida, João B. Vicente, Isabel Rivera   +16 more
doaj   +1 more source

Dichloroacetate, a pyruvate dehydrogenase kinase inhibitor, ameliorates type 2 diabetes via reduced gluconeogenesis

Heliyon, 2022
Aims: Pyruvate dehydrogenase (PDH) catalyzes the decarboxylation of pyruvate to acetyl-CoA, which plays a key role in linking cytosolic glycolysis to mitochondria metabolism.
Yuko Katayama, Yayoi Kawata, Yusuke Moritoh, Masanori Watanabe   +3 more
doaj  

Differential Contribution of Malic Enzymes during Soybean and Castor Seeds Maturation. [PDF]

PLoS ONE, 2016
Malic enzymes (ME) catalyze the decarboxylation of malate generating pyruvate, CO2 and NADH or NADPH. In some organisms it has been established that ME is involved in lipids biosynthesis supplying carbon skeletons and reducing power.
Mariel Claudia Gerrard Wheeler, Cintia Lucía Arias, Silvana Righini, Mariana Beatriz Badia, Carlos Santiago Andreo, María Fabiana Drincovich, Mariana Saigo   +6 more
doaj   +1 more source

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

Advanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez, Rajat Rai, Miryam Criado‐Gonzalez   +2 more
wiley   +1 more source