Results 61 to 70 of about 11,092 (201)

Inactivation of Pseudomonas putida KT2440 pyruvate dehydrogenase relieves catabolite repression and improves the usefulness of this strain for degrading aromatic compounds

Microbial Biotechnology
Pyruvate dehydrogenase (PDH) catalyses the irreversible decarboxylation of pyruvate to acetyl‐CoA, which feeds the tricarboxylic acid cycle. We investigated how the loss of PDH affects metabolism in Pseudomonas putida.
Renata Moreno, Luis Yuste, Gracia Morales, Fernando Rojo   +3 more
doaj   +1 more source

Fine tuning the glycolytic flux ratio of EP-bifido pathway for mevalonate production by enhancing glucose-6-phosphate dehydrogenase (Zwf) and CRISPRi suppressing 6-phosphofructose kinase (PfkA) in Escherichia coli

Microbial Cell Factories, 2021
Background Natural glycolysis encounters the decarboxylation of glucose partial oxidation product pyruvate into acetyl-CoA, where one-third of the carbon is lost at CO2.
Ying Li, He Xian, Ya Xu, Yuan Zhu, Zhijie Sun, Qian Wang, Qingsheng Qi   +6 more
doaj   +1 more source

The Functional Role of Fungi and Bacteria in Sulfur Cycling During Kelp (Ecklonia Radiata) Degradation: Unconventional Use of PiCrust2

Environmental Microbiology Reports, Volume 17, Issue 4, August 2025.
The microbial remineralization of Ecklonia radiata produces substantial amounts of climate‐relevant compounds, including dimethylsulfoniopropionate, carbon, sulphur and alkalinity. While bacterial metabolic pathways are well‐characterised and relatively predictable, fungal contributions remain underexplored due to the lack of metabolic predictive tools
Anita K. Perkins, Hans‐Peter Grossart, Keilor Rojas‐Jimenez, Alice Retter, Joanne M. Oakes   +4 more
wiley   +1 more source

Hypotaurine Reduces Glucose‐Mediated Vascular Calcification

Acta Physiologica, Volume 241, Issue 8, August 2025.
ABSTRACT Aim Vascular calcification (VC), a characteristic feature of peripheral artery disease in patients with diabetes and chronic kidney disease, has been associated with poor prognosis. We hypothesize that hyperglycemia drives VC through alterations in metabolomic and transcriptomic profiles. Methods Human coronary artery smooth muscle cells (SMCs)
Marina A. Heuschkel, Armand Jaminon, Steffen Gräber, Anna Artati, Jerzy Adamski, Joachim Jankowski, Leon Schurgers, Nikolaus Marx, Willi Jahnen‐Dechent, Claudia Goettsch   +9 more
wiley   +1 more source

pdh modulate virulence through reducing stress tolerance and biofilm formation of Streptococcus suis serotype 2

Virulence, 2019
Streptococcus suis serotype 2 (S. suis 2) is a zoonotic pathogen. It causes meningitis, arthritis, pneumonia and sepsis in pigs, leading to extremely high mortality, which seriously affects public health and the development of the pig industry.
Yang Wang, Yuxin Wang, Baobao Liu, Shaohui Wang, Jinpeng Li, Shenglong Gong, Liyun Sun, Li Yi   +7 more
doaj   +1 more source

13C Tracers for Glucose Degrading Pathway Discrimination in Gluconobacter oxydans 621H

Metabolites, 2015
Gluconobacter oxydans 621H is used as an industrial production organism due to its exceptional ability to incompletely oxidize a great variety of carbohydrates in the periplasm. With glucose as the carbon source, up to 90% of the initial concentration is
Steffen Ostermann, Janine Richhardt, Stephanie Bringer, Michael Bott, Wolfgang Wiechert, Marco Oldiges   +5 more
doaj   +1 more source

Nuclear Magnetic Resonance Approaches in the Study of 2-Oxo Acid Dehydrogenase Multienzyme Complexes—A Literature Review

Molecules, 2013
The 2-oxoacid dehydrogenase complexes (ODHc) consist of multiple copies of three enzyme components: E1, a 2-oxoacid decarboxylase; E2, dihydrolipoyl acyl-transferase; and E3, dihydrolipoyl dehydrogenase, that together catalyze the oxidative ...
Mulchand S. Patel, Sowmini Kumaran, Frank Jordan   +2 more
doaj   +1 more source

Stopped-Flow Spectrophotometric Study of the Kinetics and Mechanism of CO2 Uptake by cis-[Cr(C2O4)(BaraNH2)(OH2)2]+ Cation and the Acid-Catalyzed Decomposition of cis-[Cr(C2O4)(BaraNH2)OCO2]− Anion in Aqueous Solution

Molecules, 2011
The kinetics of CO2 uptake by the cis-[Cr(C2O4)(BaraNH2)(OH2)2]+ complex cation and the acid hydrolysis of the cis-[Cr(C2O4)(BaraNH2)OCO2]− complex anion (where BaraNH2 denotes methyl 3-amino-2,3-dideoxy-b-D-arabino-hexopyranoside) were studied using the
Lech Chmurzyński, Dagmara Jacewicz, Aleksandra Dąbrowska   +2 more
doaj   +1 more source

Development and Breeding of Herbicide‐Resistant Sorghum for Effective Cereal‐Legume Intercropping

Advanced Science, Volume 12, Issue 27, July 17, 2025.
This study identified two SbALS mutations (A93T and S624N) conferring robust herbicide resistance in sorghum, facilitating efficient weed control. Structural analysis revealed that imazamox resistance is mediated by disrupted herbicide binding. Furthermore, 126 imazamox resistant soybean varieties are screened for sorghum‐soybean intercropping ...
Sanyuan Tang, Jiayang Shi, Xuefeng Li, Mingliang Yang, Chao Li, Dan Zhang, Sen Yang, Cuo Mei, Zuyong Luo, Li Zhang, Wanke Zhang, Chunrui Zhang, Chenbo Zhu, Xiaowei Ma, Ran Xia, Yuhang Chen, Jinsong Zhang, Qingshan Chen, Shouyi Chen, Qi Xie, Feifei Yu   +20 more
wiley   +1 more source

Biosynthesis of Methanopterin in Methanobacterium thermoautotrophicum

Pteridines, 1994
The early steps in the biosynthesis of methanopterin in Methanobacterium thennoautotrophicum were analyzed by in vivo incorporation experiments of 13C labeled precursors and by enzymatic studies.
Eisenreich Wolfgang, Bacher Adelbert
doaj   +1 more source