Pyruvate dehydrogenase acetyl-transferring kinase

Results 121 to 130 of about 4,126 (159)

Deciphering the Role of Copper Homeostasis in Atherosclerosis: From Molecular Mechanisms to Therapeutic Targets. [PDF]

Int J Mol Sci
Lv X, Zhao L, Song Y, Chen W, Tuo Q.
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Validation and the role of PDK4 relevant to ferroptosis in degenerative lumbar disc disease. [PDF]

J Orthop Surg Res
Chen W +6 more
europepmc +1 more source

Lactate and lactylation in the kidneys: Current advances and prospects (Review). [PDF]

Int J Mol Med
Li X, Hu L, Hu Q, Jin H.
europepmc +1 more source

[Pyruvate dehydrogenase (acetyl-transferring)] kinase

, 2009
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Some of the next articles are maybe not open access.

Abstract MP204: Pyruvate Dehydrogenase Kinase Isozyme Specific Regulation Of Protein Acetylation In Cardiac Tissue

Circulation Research, 2021
Heart disease is the number one cause of death in developed countries. Metabolic diseases influence the severity of heart disease linked to risk factors which are thought to alter epigenetic mechanisms.
Chae-Myeong Ha, A. Wende
semanticscholar +1 more source

Inhibition of mitochondrial pyruvate dehydrogenase kinase: a proposed mechanism by which melatonin causes cancer cells to overcome cytosolic glycolysis, reduce tumor biomass and reverse insensitivity to chemotherapy

Melatonin Research, 2019
This review presents a hypothesis to explain the role of melatonin in regulating glucose metabolism in cancer cells. Many cancer cells use cytosolic glycolysis (the Warburg effect) to produce energy (ATP).
R. Reiter +5 more
semanticscholar +1 more source

Inhibition of Pyruvate Dehydrogenase Kinase as a Therapeutic Strategy against Cancer.

Current Topics in Medicinal Chemistry, 2018
Cancer cells alter their metabolism to support the uninterrupted supply of biosynthetic molecules required for continuous proliferation. Glucose metabolism is frequently reprogrammed in several tumors in addition to fatty acid, amino acid and glutamine ...
S. Sradhanjali, M. Reddy
semanticscholar +1 more source

Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors.

Journal of Proteome Research, 2018
Pyruvate dehydrogenase kinases (PDKs) dominate the critical switch between mitochondria-based respiration and cytoplasm-based glycolysis by controlling pyruvate dehydrogenase (PDH) activity.
Wen Zhang, Xiaohui Hu, W. Zhou, K. Tam
semanticscholar +1 more source