Results 341 to 350 of about 216,078 (374)

11 Pyruvate Kinase

1973
Publisher Summary This chapter describes pyruvate kinase. The enzyme has a number of attributes that make it of particular interest to various investigators. It was the first and perhaps the most clearly apparent example of an enzyme with an absolute requirement for a monovalent cation for its catalytic activity.
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The inhibition of pyruvate kinase by ATP

Biochemical and Biophysical Research Communications, 1968
Abstract The inhibition of pyruvate kinase by ATP was investigated under various conditions. It was concluded that the inhibition reported by previous workers was attributable to the magnesium complexing properties of ATP and it was shown that the inhibition was abolished completely when sufficient magnesium was added.
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Pyruvate Kinase in Human Erythrocytes

Scandinavian Journal of Haematology, 1969
The importance of efficient separation of erythrocytes from leucocytes when studying haemolysates is shown experimentally, pyruvate kinase determination given as an example. The use of the spiral centrifuge is recommended.
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Trends in kinase drug discovery: targets, indications and inhibitor design

Nature Reviews Drug Discovery, 2021
Helgi B Schiöth, Misty M Attwood, Stefan Knapp   +2 more
exaly  

Kinase drug discovery 20 years after imatinib: progress and future directions

Nature Reviews Drug Discovery, 2021
Darren Cross, Pasi A Jänne, Philip Cohen   +2 more
exaly  

Kinase inhibition in autoimmunity and inflammation

Nature Reviews Drug Discovery, 2021
Ali A Zarrin, Bruno Hochhegger, Katherine Bao   +2 more
exaly  

Isoenzymes of pyruvate kinase

Biochemical Society Transactions, 1990
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Lithium and pyruvate kinase

The Lancet, 1975
Herbert Y. Meltzer, Gordon Pscheidt
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Treatment of renal cell carcinoma: Current status and future directions

Ca-A Cancer Journal for Clinicians, 2017
Pedro Barata, Brian I Rini
exaly  

Lung cancer: New biological insights and recent therapeutic advances

Ca-A Cancer Journal for Clinicians, 2011
Suresh S Ramalingam, Taofeek K Owonikoko, Fadlo R Khuri   +2 more
exaly