Results 231 to 240 of about 95,354 (345)

Low-biomass pyruvate production with engineered Vibrio natriegens is accompanied by parapyruvate formation. [PDF]

open access: yesMicrob Cell Fact
Hädrich M   +9 more
europepmc   +1 more source

Pyruvate Carboxylase

open access: hybrid, 1966
Albert S. Mildvan   +2 more
openalex   +1 more source

HOMOTRANSPLANTATION OF THE LIVER IN HUMANS. [PDF]

open access: yes, 1963
BRITTAIN, RS   +5 more
core  

Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis

open access: yesAdvanced Science, EarlyView.
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves   +17 more
wiley   +1 more source

PCSK9 Loss‐of‐Function Disrupts Cellular Microfilament Network via LIN28A/HES5/JMY Axis in Neural Tube Defects

open access: yesAdvanced Science, EarlyView.
PCSK9 acts as a molecular chaperone promoting LIN28A lysosomal degradation. LIN28A elevates transcription factor HES5, increasing JMY expression. PCSK9 loss causes neural tube defects (NTDs) by disrupting the LIN28A/HES5/JMY axis, and high JMY disorganizes the neural progenitor cell microfilament network, leading to incomplete neural tube structure in ...
Xiaoshuai Li   +6 more
wiley   +1 more source

Pyruvate Carboxylase

open access: hybrid, 1965
Michael C. Scrutton, Merton Utter
openalex   +1 more source

A Longitudinal Study Reveals Metabolomic Markers for Individuals at Risk, Disease Severity, and Treatment Response in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
This study investigates plasma metabolomic biomarkers for rheumatoid arthritis (RA) development using longitudinal data from 209 RA patients and 56 individuals at risk. It also reveals metabolic signatures linked to severity, age, sex, and anti‐citrullinated protein autoantibody in RA.
Chenxi Zhu   +21 more
wiley   +1 more source

Home - About - Disclaimer - Privacy