Results 111 to 120 of about 13,043 (276)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Vortex Images, q-Calculus and Entangled Coherent States

Journal of Physics: Conference Series, 2012
The two circles theorem for hydrodynamic flow in annular domain bounded by two concentric circles is derived. Complex potential and velocity of the flow are represented as q-periodic functions and rewritten in terms of the Jackson q-integral. This theorem generalizes the Milne-Thomson one circle theorem and reduces to the last on in the limit q → ∞. By
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Novel notions of symmetric Hahn calculus and related inequalities

Journal of Inequalities and Applications
In this manuscript, we demonstrate a graphical comparison analysis of the classical, quantum, and symmetric quantum derivatives for any continuous function, evaluated at z = 1 $\mathfrak{z}=1$ and q = 0.5 $\mathtt{q}=0.5$ .
Saad Ihsan Butt, Muhammad Nasim Aftab, Asfand Fahad, Yuanheng Wang, Bandar Bin Mohsin   +4 more
doaj   +1 more source

Hybrid error estimates of Weddle's formula and their applications for various classes of functions

Ain Shams Engineering Journal
This study presents new bounds on Weddle's type formula for differentiable functions using proportional Caputo-Hybrid operators (Pcap). These operators provide hybrid estimates; for α=1, they yield first-derivative estimates, while for α=0, they ...
Muhammad Umar, Saad Ihsan Butt, Dawood Khan, Sanja Tipurić-Spužević, Youngsoo Seol   +4 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Proof of the Refined Alternating Sign Matrix Conjecture

, 1996
Mills, Robbins, and Rumsey conjectured, and Zeilberger proved, that the number of alternating sign matrices of order $n$ equals $A(n):={{1!4!7! ... (3n-2)!} \over {n!(n+1)! ... (2n-1)!}}$. Mills, Robbins, and Rumsey also made the stronger conjecture that
Zeilberger, Doron
core   +3 more sources