Design and synthesis of carbazole-acrylamide-pyridinium hybrids as dual acetylcholinesterase/butyrylcholinesterase inhibitors and evaluation of their cytotoxic profile on SH-SY5Y and HEK293 cell lines. [PDF]
Taherkhani AM +12 more
europepmc +1 more source
ABSTRACT Background Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) is a minimally invasive therapy for drug‐resistant focal epilepsy. However, the relationship between specific seizure‐onset patterns (SOPs), particularly low‐voltage fast activity (LVFA), and postoperative scalp EEG normalization remains inadequately ...
Yi‐qing Yang +6 more
wiley +1 more source
Identification of Changes in Gene Expression. [PDF]
Ameis L, Möllenhoff K.
europepmc +1 more source
Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li +17 more
wiley +1 more source
Mathematical Modeling of 6‑APA Production by Enzymatic Hydrolysis of Penicillin G in a Batch Reactor. [PDF]
Álvares LEAE +6 more
europepmc +1 more source
International audienceIn the context of autoregressive linear process, with exogenous random variables, say ARHX (p, q, k), We envisage derivative of order p, exogenous random variables of order q and k fixed jumps.
Bosq, Denis
core
Efficacy of Fampridine on Refractory Optic Neuritis in Neuromyelitis Optica Spectrum Disorders
ABSTRACT Background Neuromyelitis optica spectrum disorders (NMOSD) usually occur with acute refractory optic neuritis (ON). However, there is a lack of efficacious treatments to improve recovery. Since fampridine has been found to improve the prognosis of multiple sclerosis (MS) and MS‐related ON, it is necessary to explore the efficacy of fampridine ...
Hongxuan Wang +9 more
wiley +1 more source
Quadrature solution of fractional coupled burgers and plankton-oxygen dynamics under climate change. [PDF]
Zayed MA +6 more
europepmc +1 more source
Parkinson Disease Subtype Stability and Eventual Convergence
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Laura M. Rosok +10 more
wiley +1 more source
A Novel 2,7-Naphthyridine Derivative Suppresses Ovarian Cancer Cell Growth Through G1 Cell Cycle Arrest, Apoptosis Induction and Migration Inhibition. [PDF]
Chabowska G +8 more
europepmc +1 more source

