Results 41 to 50 of about 943 (143)

Functionally related internal fluctuations in human ileal bile acid‐binding protein by high pressure nuclear magnetic resonance

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Hidden protein states with partially unfolded regions can have a functional relevance and may also contribute to an uncontrolled self‐association of proteins leading to pathological conditions. Human ileal bile acid‐binding protein (hI‐BABP), a member of the family of intracellular lipid‐binding proteins (iLBPs), plays a key role in the ...
Tamara Teski   +4 more
wiley   +1 more source

The environmental and economic implications of the climate change and extractive industry nexus in Africa [PDF]

open access: yesEnvironmental Economics, 2016
Climate change and extractive industry are two important global streams that are linked to each other in that risks associated with the former can adversely affect different areas of the extractive sector, while the activities of the latter can ...
Ademola Oluborode Jegede
doaj   +1 more source

Structural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1170-1181, June 2026.
ABSTRACT Iron homeostasis in various pathogenic bacteria is regulated by bacterioferritins (Bfr) which function to store Fe3+ and release Fe2+ as needed for metabolic processes. The Bfr structure consists of 18 kDa subunits in which dimer pairs bind a heme molecule and are assembled into a highly symmetrical 24‐meric spherical structure with an ...
Lijun Liu   +9 more
wiley   +1 more source

Economic Complexity as a Determinant of Green Development in the Central and Eastern European (CEE) Countries

open access: yesStudia Universitatis Vasile Goldis Arad, Seria Stiinte Economice
The paper analyses the determinants of green development in the Central and Eastern European (CEE) countries pointing out the influence of the sophistication of productive structure and exported goods (economic complexity).
Neagu Olimpia, Neagu Mădălin-Ioan
doaj   +1 more source

Genome-wide association analysis reveals a novel QTL CsPC1 for pericarp color in cucumber

open access: yesBMC Genomics, 2022
Background Cucumber is an important melon crop in the world, with different pericarp colors. However, the candidate genes and the underlying genetic mechanism for such an important trait in cucumber are unknown.
Hongyu Huang   +11 more
doaj   +1 more source

On Gamification in the Context of Education: A Systematic Review and Evaluation Framework

open access: yesComputer Applications in Engineering Education, Volume 34, Issue 3, May 2026.
ABSTRACT The application of gamification techniques in education is becoming increasingly common across different educational stages and disciplines. However, the widespread acceptance of their benefits leads to their implementation without verifying whether these benefits occur, what they are, and to what extent.
Javier Muñoz‐Calle   +3 more
wiley   +1 more source

Structural insights into how vacuolar sorting receptor recognizes the C‐terminal sorting determinant of a vicilin‐like seed storage protein

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 257-270, January 2026.
Soluble cargo proteins are sorted to the vacuoles via a receptor‐mediated mechanism. Combining crystallographic and mutagenesis studies, we showed how the C‐terminal sorting determinant (ctVSD) of vicilin‐like seed storage protein VL22 is recognized by the protease‐associated domain of Arabidopsis vacuolar‐sorting receptor 1.
Shu Nga Lui   +4 more
wiley   +1 more source

Barriers to Changing Sedation Practice for Patients Undergoing Mechanical Ventilation on the Intensive Care Unit: A Qualitative Interview Study of Clinical Staff

open access: yesNursing in Critical Care, Volume 31, Issue 1, January 2026.
ABSTRACT Background Medical sedation is a requirement for mechanical ventilation for most patients admitted to the intensive care unit (ICU). Sedation can help minimise patient discomfort, pain and distress, but can lead to hypotension, bradycardia, prolonged ventilation and delirium.
Nicholas D. Richards   +2 more
wiley   +1 more source

Health‐Related Quality of Life in Patients With a Head and Neck Sarcoma: A Mixed‐Methods Study

open access: yesHead &Neck, Volume 47, Issue 11, Page 3086-3097, November 2025.
ABSTRACT Background Patients with head and neck sarcomas (HNS) face unique health‐related quality of life (HRQoL) challenges due to its disease rarity. This study examined and identified the prevalence of generic‐ and location‐specific HRQoL issues.
E. Koffi   +25 more
wiley   +1 more source

Real‐world lecanemab adoption in Japan 1 year after launch: Insights from 311 specialists on infrastructure and reimbursement barriers

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Lecanemab was approved for early Alzheimer's disease in Japan, with ≈ 6000 patients treated in the first year post approval. This study explores real‐world practices, challenges, and potential solutions. METHODS We conducted an anonymized online survey of clinical specialists authorized to prescribe lecanemab, obtaining responses ...
Kenichiro Sato   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy