Results 41 to 50 of about 943 (143)
Abstract Hidden protein states with partially unfolded regions can have a functional relevance and may also contribute to an uncontrolled self‐association of proteins leading to pathological conditions. Human ileal bile acid‐binding protein (hI‐BABP), a member of the family of intracellular lipid‐binding proteins (iLBPs), plays a key role in the ...
Tamara Teski +4 more
wiley +1 more source
The environmental and economic implications of the climate change and extractive industry nexus in Africa [PDF]
Climate change and extractive industry are two important global streams that are linked to each other in that risks associated with the former can adversely affect different areas of the extractive sector, while the activities of the latter can ...
Ademola Oluborode Jegede
doaj +1 more source
Structural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus
ABSTRACT Iron homeostasis in various pathogenic bacteria is regulated by bacterioferritins (Bfr) which function to store Fe3+ and release Fe2+ as needed for metabolic processes. The Bfr structure consists of 18 kDa subunits in which dimer pairs bind a heme molecule and are assembled into a highly symmetrical 24‐meric spherical structure with an ...
Lijun Liu +9 more
wiley +1 more source
The paper analyses the determinants of green development in the Central and Eastern European (CEE) countries pointing out the influence of the sophistication of productive structure and exported goods (economic complexity).
Neagu Olimpia, Neagu Mădălin-Ioan
doaj +1 more source
Genome-wide association analysis reveals a novel QTL CsPC1 for pericarp color in cucumber
Background Cucumber is an important melon crop in the world, with different pericarp colors. However, the candidate genes and the underlying genetic mechanism for such an important trait in cucumber are unknown.
Hongyu Huang +11 more
doaj +1 more source
On Gamification in the Context of Education: A Systematic Review and Evaluation Framework
ABSTRACT The application of gamification techniques in education is becoming increasingly common across different educational stages and disciplines. However, the widespread acceptance of their benefits leads to their implementation without verifying whether these benefits occur, what they are, and to what extent.
Javier Muñoz‐Calle +3 more
wiley +1 more source
Soluble cargo proteins are sorted to the vacuoles via a receptor‐mediated mechanism. Combining crystallographic and mutagenesis studies, we showed how the C‐terminal sorting determinant (ctVSD) of vicilin‐like seed storage protein VL22 is recognized by the protease‐associated domain of Arabidopsis vacuolar‐sorting receptor 1.
Shu Nga Lui +4 more
wiley +1 more source
ABSTRACT Background Medical sedation is a requirement for mechanical ventilation for most patients admitted to the intensive care unit (ICU). Sedation can help minimise patient discomfort, pain and distress, but can lead to hypotension, bradycardia, prolonged ventilation and delirium.
Nicholas D. Richards +2 more
wiley +1 more source
Health‐Related Quality of Life in Patients With a Head and Neck Sarcoma: A Mixed‐Methods Study
ABSTRACT Background Patients with head and neck sarcomas (HNS) face unique health‐related quality of life (HRQoL) challenges due to its disease rarity. This study examined and identified the prevalence of generic‐ and location‐specific HRQoL issues.
E. Koffi +25 more
wiley +1 more source
Abstract INTRODUCTION Lecanemab was approved for early Alzheimer's disease in Japan, with ≈ 6000 patients treated in the first year post approval. This study explores real‐world practices, challenges, and potential solutions. METHODS We conducted an anonymized online survey of clinical specialists authorized to prescribe lecanemab, obtaining responses ...
Kenichiro Sato +12 more
wiley +1 more source

