Results 101 to 110 of about 2,062,225 (372)

Type I Interferon Pathway Activation Disrupts Monocyte Maturation and Enhances Immune Evasion in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
This study shows that monocytes in multiple myeloma display an excessive interferon response, leading to transcriptional reprogramming and altered differentiation. Using single‐cell sequencing, coculture experiments, and patient samples before and after therapy, the authors demonstrate that induction treatment reduces this interferon response ...
Jian Cui   +18 more
wiley   +1 more source

Diversity of Rickettsia species in collected ticks from Southeast Iran

open access: yesBMC Veterinary Research
Rickettsia occurs worldwide and rickettsiosis is recognized as an emerging infection in several parts of the world. Ticks are reservoir hosts for pathogenic Rickettsia species in humans and domestic animals.
Ali Qorbani   +5 more
doaj   +1 more source

Retrospective Examination of Q Fever Endocarditis: An Underdiagnosed Disease in the Mainland of China

open access: yesChinese Medical Journal, 2017
Background: Q fever endocarditis, a chronic illness caused by Coxiella burnetii, can be fatal if misdiagnosed or left untreated. Despite a relatively high positive rate of Q fever serology in healthy individuals in the mainland of China, very few cases ...
Xiao Han   +10 more
doaj   +1 more source

Identifikasi Coxiella Brunetii Menggunakan Pengujian Polymerase Chain Reaction pada Kambing di Kota Kupang [PDF]

open access: yes, 2014
Identification of Coxiella brunetii using polymerase chain reaction method in goats in Kupang area at Nusa Tenggara Timur had been done. Coxiella burnetii as causative of Q fever zoonosis in human and livestock and become public health problem.
Detha, A. I. (Annytha)
core  

Attention, predictive learning, and the inverse base-rate effect: Evidence from event-related potentials [PDF]

open access: yes, 2014
We report the first electrophysiological investigation of the inverse base-rate effect (IBRE), a robust non-rational bias in predictive learning. In the IBRE, participants learn that one pair of symptoms (AB) predicts a frequently occurring disease ...
Hemmings, Y   +3 more
core   +2 more sources

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

open access: yesAdvanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun   +14 more
wiley   +1 more source

Geoadditive Latent Variable Modelling of Child Morbidity and Malnutrition in Nigeria [PDF]

open access: yes, 2008
Investigating the impact of important risk factors and geographical location on child morbidity and malnutrition is of high relevance for developing countries. Previous research has usually carried out separate regression analyses for certain diseases or
Fahrmeir, Ludwig, Khatab, Khaled
core   +1 more source

Clinical characteristics of acute Q fever patients in South Korea and time from symptom onset to serologic diagnosis

open access: yesBMC Infectious Diseases, 2019
BackgroundAcute Q fever usually presents as a nonspecific febrile illness, and its occurrence is rapidly increasing in South Korea. This study investigated the clinical characteristics of acute Q fever patients in South Korea and the time from symptom ...
J. Heo   +7 more
semanticscholar   +1 more source

DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition

open access: yesAdvanced Science, EarlyView.
A honeycomb‐shaped DNA nanostructure is introduced that organizes nanobodies or aptamers into trimeric clusters mirroring the native hemagglutinin arrangement on influenza viruses. This geometry‐matched multivalency enhances binding avidity by up to 1000‐fold, resulting in robust, broad‐spectrum viral neutralization and a 30–55% improvement in host ...
Saurabh Umrao   +8 more
wiley   +1 more source

Systemic inflammatory response syndrome (SIRS) after extracorporeal membrane oxygenation (ECMO): Incidence, risks and survivals. [PDF]

open access: yes, 2016
INTRODUCTION: Systemic inflammatory response syndrome (SIRS) is frequently observed after extracorporeal membrane oxygenation (ECMO) decannulation; however, these issues have not been investigated well in the past. METHODS: Retrospective chart review was
Baram, Michael   +4 more
core   +2 more sources

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