Results 31 to 40 of about 346,548 (234)

First report of Q fever in Oman. [PDF]

, 2000
Although serologic evidence suggests the presence of Q fever in humans and animals in Saudi Arabia and the United Arab Emirates, acute Q fever has not been reported on the Arabian Peninsula.
Al Dhahry, S. H., El-Khatim, H. S., John, V., Johnston, W. J., Musa, M., Scrimgeour, E. M.   +5 more
core   +2 more sources

Advancements in Bio‐Integrated Flexible Electronics for Hemodynamic Monitoring in Cardiovascular Healthcare

Advanced Science, EarlyView.
This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley   +1 more source

Q Fever: characteristics and reports of an important neglected zoonosis in Brazil / Febre Q: características e relatos de uma importante zoonose negligenciada no Brasil [PDF]

, 2022
The Q fever is a zoonotic disease neglected in many countries all over the world. This zoonosis is caused by the bacteria Coxiella burnetii, a pathogen that presents stability and environmental resistance with high capacity to cause human infection ...
Corrêa, José Otávio do Amaral, Guimarães, Ricardo José de Paula Souza e, Meurer, Igor Rosa, Silva, Marcio Roberto, Vanelli, Chislene Pereira   +4 more
core  

Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System

Advanced Science, EarlyView.
This study introduces a novel approach combining molecular dynamics simulations and neural network modeling to predict the Cas12a trans‐cleavage activity. By integrating sequence and molecular interaction features, prediction accuracy is enhanced, and identify key features affecting Cas12a trans‐cleavage activity.
Zhihao Yao, Wanglu Li, Kaiyu He, Hongmei Wang, Yan Xu, Qun Wu, Liu Wang, Yao Nie   +7 more
wiley   +1 more source

Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease

Advanced Science, EarlyView.
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su, Guoqing Wu, Muya Xiong, Yuhang Wang, Junyuan Cao, Mengyuan You, Yingchun Xiang, Tianqing Nie, Minjun Li, Gengfu Xiao, Leike Zhang, Qiang Shao, Yechun Xu   +12 more
wiley   +1 more source

Q fever endocarditis masquerading as Mixed cryoglobulinemia type II. A case report and review of the literature [PDF]

, 2006
BACKGROUND: The clinical manifestations of Q fever endocarditis are protean in nature. Mixed cryoglobulinemia type II is rarely a facet of the presenting clinical manifestations of Q fever endocarditis.
A Stein, B Granel, BI Lev, Christos A Fourlas, D Raoult, D Raoult, EF Berbari, H Coponat-Vacher, H Torley, JV Graham, M Ghassemi, P Bichard, P Brouqui, P Houpikian, PE Fournier, Petros I Rafailidis, RJ Enzenauer, Spiros P Dourakis, TJ Marrie, Y Siegman-Igra   +19 more
core   +3 more sources

DDX3 Regulates the Cap‐Independent Translation of the Japanese Encephalitis Virus via Its Interactions with PABP1 and the Untranslated Regions of the Viral Genome

Advanced Science, EarlyView.
Japanese encephalitis virus (JEV) employs a cap‐independent (CI) translation strategy to evade host translational shutoff. During the shut‐off of host cellular canonical translation, DEAD‐box protein 3 (DDX3) bind to JEV UTRs to establish a closed‐loop architecture, and its interaction with poly(A)‐binding protein 1 (PABP1) to form DDX3/PABP1/eIF4G ...
Chenxi Li, Linjie Zhang, Chenyang Tang, Xuan Chen, Jing Shi, Qingyu Li, Xue Jiao, Jinyao Guo, Bin Wang, Kefan Bu, Abdul Wahaab, Yuguo Yuan, Ming‐an Sun, Yanhua Li   +13 more
wiley   +1 more source

Q Fever in Greenland

Emerging Infectious Diseases, 2010
We report a patient with Q fever endocarditis in a settlement in eastern Greenland (Isortoq, Ammassalik area). Likely animal sources include sled dogs and seals. Q fever may be underdiagnosed in Arctic areas but may also represent an emerging infection.
Koch, Anders, Svendsen, Claus Bo, Christensen, Jens Jorgen, Bundgaard, Henning, Møller, Lars Emil Vindfeld, Christiansen, Claus Bohn, Kemp, Michael, Villumsen, John Steen   +7 more
openaire   +5 more sources

Mercaptophenylboronic Acid‐Mediated Nanozyme Immunochromatographic Assay for Simultaneous Detection of Respiratory Bacteria and Virus

Advanced Science, EarlyView.
This study developes a universal colorimetric ICA platform that integrates broad‐spectrum recognition by 4‐mercaptophenylboronic acid with dual signal enhancement—both colorimetric and catalytic—mediated by a biomimetic magnetic nanozyme. This platform, for the first time, enables simple, convenient, ultrasensitive, and simultaneous screening of ...
Qing Yu, Jiaxuan Li, Shuai Zheng, Yajin Hu, Benshun Tian, Meirou Lu, Bing Gu, Chongwen Wang   +7 more
wiley   +1 more source

Pediatric Q Fever

Current Infectious Disease Reports, 2020
The non-specific presentation of acute Q fever makes it difficult to diagnose in children, but untreated Q fever can result in chronic infections that have severe complications.Pediatric Q fever cases continue to be infrequently reported in the literature, and primarily document cases of persistent infections with Coxiella burnetii.
Cara C. Cherry, Gilbert J. Kersh
openaire   +3 more sources