Results 71 to 80 of about 2,062,225 (372)

Epidemiological investigation and physician awareness regarding the diagnosis and management of Q fever in South Korea, 2011 to 2017.

PLoS Neglected Tropical Diseases, 2021
BackgroundIn South Korea, the number of Q fever cases has rapidly increased since 2015. Therefore, this study aimed to characterize the epidemiological and clinical features of Q fever in South Korea between 2011 and 2017.Methods/principal findingsWe ...
Yong Chan Kim, Hye Won Jeong, Dong-Min Kim, Kyungmin Huh, Sang-Ho Choi, Hee Young Lee, Yunjung Jung, Yeol Jung Seong, Eun Jin Kim, Young Hwa Choi, Jung Yeon Heo   +10 more
doaj   +1 more source

Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine

Frontiers in Immunology, 2019
Coxiella burnetii, the causative agent of Q fever, is a Gram-negative intracellular bacterium transmitted via aerosol. Regulatory approval of the Australian whole-cell vaccine Q-VAX® in the US and Europe is hindered by reactogenicity in previously ...
A. Scholzen, Guilhem Richard, L. Moise, L. Baeten, P. Reeves, W. Martin, Timothy Brauns, C. Boyle, Susan Raju Paul, R. Bucala, R. Bowen, A. Garritsen, Anne Searls De Groot, A. Sluder, M. Poznansky   +14 more
semanticscholar   +1 more source

Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization

Advanced Materials, EarlyView.
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu, Qi Lu, Yong Ren, Priyadharshini Balasubramanian, Kazem Ebadi Jalal, Hannah Klug, Matthias Klein, Toszka Bohn, Tobias Bopp, Fedor Jelezko, Yingke Wu, Tanja Weil   +11 more
wiley   +1 more source

Molecular and serological survey of Brucella spp. among rodents in western Iran

BMC Veterinary Research
Introduction and purpose Brucellosis is a prevalent bacterial zoonosis globally, affecting a broad range of hosts. The role of rodents in the survival and transmission of Brucella species to humans remains uncertain.
Majid Hemati, Mohammad Khalili, Saber Esmaeili, Ahmad Mahmoudi, Hossein Ahangari Cohan, Ehsan Mostafavi   +5 more
doaj   +1 more source

Organisation of Health Care During an Outbreak of Marburg Haemorrhagic Fever in the Democratic Republic of Congo, 1999. [PDF]

, 2004
Organising health care was one of the tasks of the International Scientific and Technical Committee during the 1998-1999 outbreak in Durba/Watsa, in the north-eastern province (Province Orientale), Democratic Republic of Congo.
Borchert, M, Colebunders, R, Kinuani, L, Libande, M, Mustin, J P, Muyembe-Tamfum, J J, Olinda, L A, Pirard, P, Sleurs, H, Tshioko, F, Tshomba, A   +10 more
core   +2 more sources

Clinical Features and Complications of Coxiella burnetii Infections From the French National Reference Center for Q Fever

JAMA Network Open, 2018
Key Points Question What are the characteristics and clinical presentations of Coxiella burnetii infection using 21st-century–clarified definitions? Finding In a cohort study of 2434 patients with Q fever, the following new critical Q fever foci were ...
C. Melenotte, C. Protopopescu, M. Million, S. Edouard, M. P. Carrieri, C. Eldin, E. Angelakis, F. Djossou, N. Bardin, P. Fournier, J. Mege, D. Raoult   +11 more
semanticscholar   +1 more source

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source

Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages [PDF]

, 2018
Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole ...
Clemente, Tatiana M., Gilk, Stacey D., Justis, Anna V., Mulye, Minal, Nallandhighal, Srinivas, Tran, Tuan M.   +5 more
core   +1 more source

Airborne geographical dispersal of Q fever from livestock holdings to human communities: a systematic review and critical appraisal of evidence

BMC Infectious Diseases, 2018
BackgroundQ fever is a zoonotic disease caused by Coxiella burnetii. This bacterium survives harsh conditions and attaches to dust, suggesting environmental dispersal is a risk factor for outbreaks.
N. Clark, R. S. Soares Magalhães
semanticscholar   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source