Results 151 to 160 of about 2,263 (203)

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett   +7 more
wiley   +1 more source

Stability of Medicinal Nanoemulsions to Spaceflight: Insights From the StarMed Experiment

open access: yesAdvanced Healthcare Materials, EarlyView.
Chitosan‐coated melatonin nanoemulsions (MN) recovered from a sounding rocket mission preserve droplet size and controlled‐release behavior, whereas uncoated nanoemulsions show ageing‐driven droplet growth and increased accessible drug fraction. Simple polymer coatings thus enhance the flight resilience of liquid space medicines under cumulative launch
Modupe Adebowale   +4 more
wiley   +1 more source

Wearable OLED‐Assisted Photodynamic Cancer Therapy Using Chlorin e6‐Loaded Pluronic Nanocapsules as Photosensitizers

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel photodynamic therapeutic approach has been employed for anticancer therapy, utilizing chlorin e6‐loaded Pluronic nanocapsules and a wearable organic light‐emitting diode light source. This has shown significant in vivo antitumor efficacy with minimal off‐target toxicity. The innovative combination of a wearable light source and photosensitizers
Hyeryeon Oh   +7 more
wiley   +1 more source

Multifunctional Thiolated Hyaluronic Acid‐graft‐PEDOT Dressing With Antifouling, On‐Demand Drug Delivery and Electrical Stimulation for Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
A multifunctional P(EDOT‐co‐EDOT‐g‐THA) dressing acts as a dynamic biointerface integrating antifouling capability, on‐demand drug delivery, and electrical stimulation. It achieves electrochemically triggered thiolated hyaluronic acid (THA) release while modulating cellular responses for wound healing application.
Jingwen Yang   +8 more
wiley   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira   +8 more
wiley   +1 more source

Q Methodology

EdTechnica, 2023
Q Methodology is a unique approach to research tailored for discerning and quantifying subjective perspectives. Developed by Stephenson (1935) in response to perceived reductionism in the psychological and social sciences, it prioritizes the individual's unique perspective rather than generalized characteristics seen across large populations.
Brandy Walker   +2 more
openaire   +2 more sources

Q methodology

Nurse Researcher, 1997
Q methodology is more than just a technique for assessing attitudes. It is an approach which has subjectivity as its central focus and aims to allow researchers to present the views and perspectives of different people without insisting on the 'superior', more 'objective' status of the researcher's own construction of reality ( 1 ).
L, Cordingley, C, Webb, V, Hillier
  +6 more sources

Q Methodology

2008
Q methodology is a mixed blessing. No doubt about it. Any method which has such an openly qualiquantological heritage (see Stenner and Stainton Rogers (2004) for a fuller explanation of this disgraceful neologism) risks being singled out and victimized.
Stenner, Paul, Watts, S., Worrell, M.
openaire   +2 more sources

An introduction to Q methodology

Nurse Researcher, 2013
To explain Q methodology, an untraditional approach to nursing research, by exploring the various stages involved in it and using two studies.Q has some of the advantages of qualitative and quantitative, methodologies. A defining principle of Q is its assumption that subjective viewpoints are amenable to systematic analysis.
openaire   +2 more sources

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