Results 1 to 10 of about 39,340 (291)
Measurement, modeling and QALYs [version 1; peer review: 2 approved] [PDF]
F1000Research, 2020 Over the past 30 years, a mainstay of health technology assessment has been the creation of modeled incremental cost-per-quality adjusted life year (QALY) claims. These are intended to inform resource allocation decisions.
Paul C. Langley, Stephen P. McKenna
doaj +3 more sources
Environment International, 2019 PM2.5-bound toxic metals (TMs) are derived from various sources, and they can cause many adverse health effects on the human body. To effectively reduce the disease burden of TMs by controlling the relative sources, an integrated approach of quality ...
Jianwei Liu
exaly +3 more sources
QALYs: The Math Doesn’t Work [PDF]
Journal of Health Economics and Outcomes Research, 2023 The quality-adjusted life-year (QALY) is a metric widely used when assessing the cost-effectiveness of drugs and other health interventions. The assessments are used in the development of recommendations for pricing, formulary placement decisions, and ...
Tia G. Sawhney +2 more
doaj +2 more sources
Health Technology Assessment, 2023 Background Acute hypoxaemic respiratory failure requiring mechanical ventilation is a major cause of morbidity and mortality and has significant resource implications in terms of intensive care unit and hospital stay.
Ashley Agus +3 more
doaj +1 more source
The estimated disease burden of COVID-19 in Japan from 2020 to 2021
Journal of Infection and Public Health, 2023 Background: To date, it is not fully understood to what extent COVID-19 has burdened society in Japan. This study aimed to estimate the total disease burden due to COVID-19 in Japan during 2020–2021.
Shinya Tsuzuki, Philippe Beutels
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Frontiers in Oncology, 2022 BackgroundIn this study, compared to sunitinib as one of the available treatment options, we aimed to evaluate the cost-effectiveness of lenvatinib plus pembrolizumab or everolimus as first-line treatment for advanced renal cell carcinoma (RCC) patients ...
Ye Wang +4 more
doaj +1 more source
Health and Quality of Life Outcomes, 2015 Measuring health and health-related quality of life (HRQoL) is important for tracking the health of individuals and populations over time. Generic HRQoL measures allow for comparison across health conditions. One form of generic HRQoL measures are profile measures, which provide a description of health across several different domains (such as physical
Janel Hanmer +9 more
openaire +4 more sources
“The trouble with QALYs…” [PDF]
Epidemiology and Psychiatric Sciences, 2007 AbstractThis paper summarises the use of QALYs in evaluating changes in mental health states, highlighting the benefits and challenges of their use in this field. The general principles underlying the QALY measure and the most common methods of measuring QALYs are discussed briefly.
Knapp, M, Mangalore, R
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QJM, 2010 Current regulation of drug approvals has caused considerable controversy as entrusted to the National Institute of Clinical Excellence, and has led to a lack of availability of modern medicines on the basis of calculations made of 'value'.We have examined the assessment tool used by National Institute of Clinical Excellence (NICE) to establish the cost
R, Kirkdale +4 more
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INNOVATIONS in Pharmacy, 2020 All too often organizations embrace standards for health technology assessment that fail to meet the standards of normal science. A continuing puzzle is why the axioms of fundamental measurement are ignored by researchers such as the University of ...
Paul Langley
doaj +1 more source