Results 11 to 20 of about 202,914 (136)

A Whole-Genome Sequencing Association Study of Low Bone Mineral Density Identifies New Susceptibility Loci in the Phase I Qatar Biobank Cohort [PDF]

open access: yesJournal of Personalized Medicine, 2021
Introduction: Bone density disorders are characterized by a reduction in bone mass density and strength, which lead to an increase in the susceptibility to sudden and unexpected fractures. Despite the serious consequences of low bone mineral density (BMD)
Marawan Abu-Madi   +2 more
exaly   +6 more sources

The Qatar Biobank: background and methods [PDF]

open access: yesBMC Public Health, 2015
Background: The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to 60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 years) aged ≥18 years ...
Elio Riboli, Queenie Chan, Heather Ward
exaly   +5 more sources

Smoking shapes the relationship between metabolic biomarkers and femoral-neck bone mineral density: A stratified analysis by smoking status [PDF]

open access: yesTobacco Induced Diseases
Introduction Bone mineral density (BMD) is a crucial indicator of bone strength and osteoporosis risk. Smoking is known to negatively impact bone health and related bone metabolism biomarkers.
Amal M. Hassan   +4 more
doaj   +2 more sources

Accelerating heat stress and human survivability risk in Qatar [PDF]

open access: yes
Background: Rising temperatures and humidity in arid regions like Qatar are amplifying heat stress risks, posing significant threats to population health. Wet bulb temperature (Tw), which combines air temperature and humidity, is a key indicator of human
Mourshed, Monjur   +3 more
core   +6 more sources

Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2

open access: yesStem Cell Research, 2021
Alzheimer's disease (AD) is the major cause of dementia worldwide. Early-onset familial AD accounts for about 0.5% of all AD and is caused by single major gene mutations and autosomal dominant inheritance.
Hany E. Marei   +6 more
doaj   +1 more source

Qatar Biobank: COVID-19 biorepository project [PDF]

open access: yes, 2021
Background: The rapid spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its resulting disease (COVID-19) is one of the greatest global public health crisis of the recent decades 1 .
Afifi, Nahla   +5 more
core   +1 more source

The QChip1 knowledgebase and microarray for precision medicine in Qatar

open access: yesnpj Genomic Medicine, 2022
Risk genes for Mendelian (single-gene) disorders (SGDs) are consistent across populations, but pathogenic risk variants that cause SGDs are typically population-private.
Juan L. Rodriguez-Flores   +27 more
doaj   +1 more source

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