Results 1 to 10 of about 20,590 (100)

KEYNOTE-991: pembrolizumab plus enzalutamide and androgen deprivation for metastatic hormone-sensitive prostate cancer.

open access: yesFuture Oncology, 2023
Current treatment for patients with metastatic hormone-sensitive prostate cancer (mHSPC) delays disease progression and improves survival, but resistance is inevitable. Additional therapies that prolong survival are needed.
C. Gratzke   +8 more
semanticscholar   +1 more source

Removal of Microcystis aeruginosa cells using the dead cells of a marine filamentous bacterium, Aureispira sp. CCB-QB1

open access: yesPeerJ, 2022
Inorganic and synthetic flocculants are widely investigated for removing harmful microalgae, such as Microcystis aeruginosa. However, their toxicity and non-biodegradability are shortcomings.
G. Furusawa, K. Iwamoto
semanticscholar   +1 more source

Inhibition of basal and glucagon-induced hepatic glucose productionby 991 and other pharmacological AMPK activators.

open access: yesBiochemical Journal, 2022
Pharmacological AMPK activation represents an attractive approach for the treatment of type 2 diabetes (T2D). AMPK activation increases skeletal muscle glucose uptake, but there is controversy as to whether AMPK activation also inhibits hepatic glucose ...
M. Johanns   +13 more
semanticscholar   +1 more source

A new K+channel-independent mechanism is involved in the antioxidant effect of XE-991 in an in vitro model of glucose metabolism impairment: implications for Alzheimer’s disease

open access: yesCell Death Discovery, 2022
Alzheimer’s disease (AD) is a neurodegenerative disorder that represents the first cause of dementia. Although there has been significant progress in AD research, the actual mechanisms underlying this pathology remain largely unknown. There is increasing
S. Piccirillo   +6 more
semanticscholar   +1 more source

Satellite orbit under influence of a drag - analytical approach [PDF]

open access: yesSerbian Astronomical Journal, 2017
The report studies some changes in orbital elements of the artificial satellites of Earth under influence of atmospheric drag. In order to develop possibilities of applying the results in many future cases, an analytical interpretation of the ...
Martinović M.M., Šegan S.D.
doaj   +1 more source

The proximities of asteroids and critical points of the distance function [PDF]

open access: yesSerbian Astronomical Journal, 2010
The proximities are important for different purposes, for example to evaluate the risk of collisions of asteroids or comets with the Solar-System planets.
Milisavljević Slaviša
doaj   +1 more source

Sarcoma of the Breast: Clinical Characteristics and Outcomes of 991 Patients from the National Cancer Database

open access: yesSarcoma, 2021
Background Sarcoma of the breast is a rare malignancy with heterogeneous histology. Angiosarcoma, including secondary angiosarcoma from previous radiation, is the most common type of sarcoma of the breast.
J. S. Lee, K. Yoon, M. Onyshchenko
semanticscholar   +1 more source

Stark broadening parameter tables for Ne II and Ne III spectral lines [PDF]

open access: yesSerbian Astronomical Journal, 2001
Using a semiclassical approach, we have calculated electron-, proton-, He II-, Mg II-, Si II- and Fe II-impact line widths and shifts for 10 Ne II and 6 Ne III multiplets as a function of temperature and perturber density.
Dimitrijević M.S.
doaj   +1 more source

A FABRY-PEROT METARESONATOR SUPPORTING TRAPPED-MODE RESONANCES [PDF]

open access: yesRadio Physics and Radio Astronomy, 2021
Purpose: Investigation of the electrodynamic properties of a Fabry-Perot metaresonator formed by two parallel perfectly conducting, two-dimensionally periodic, two-element screens of finite thickness with rectangular holes.
A. V. Gribovsky
doaj   +1 more source

DFNA5 (GSDME) c.991-15_991-13delTTC: Founder Mutation or Mutational Hotspot?

open access: yesInternational Journal of Molecular Sciences, 2020
Deafness due to mutations in the DFNA5 gene is caused by the aberrant splicing of exon 8, which results in a constitutively active truncated protein. In a large family of European descent (MORL-ADF1) segregating autosomal dominant nonsyndromic hearing ...
K. Booth, H. Azaiez, Richard J. H. Smith
semanticscholar   +1 more source

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