Results 241 to 250 of about 95,719 (293)

Functionalized Quantum Dot-Based Portable Sensor for Dual Detection of Stress Biomarkers in Blood Serum and Saliva. [PDF]

J Biophotonics
Kishore A, Varughese AM, Roth B, Zeilinger C.   +3 more
europepmc   +1 more source

Dynamic Analysis of Electrically Assisted Turbocharger Rotor Considering Contact Effects in Nut Structures

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT The rotor system of an electrically assisted turbocharger (EAT) is composed of multiple shaft components; The nonlinear connection and contact effects make it difficult to determine the system dynamic characteristics. To improve the modeling accuracy of EAT rotor system and evaluate the influence of contact between multi‐axis components and ...
Wenchao Liang, Shuqian Cao, Xiaolin Cao, Mingyue Hu, Yanhong Kang, Tianyou Wang   +5 more
wiley   +1 more source

Phase 1 study of zanubrutinib plus lenalidomide for patients with relapsed/refractory diffuse large B-cell lymphoma. [PDF]

Blood Adv
Song Z, Cheng Y, Yang H, Zhang L, Zou L, Guo Y, Cao J, Huang H, Wang Z, Huang S, Fang Y, Lyu J, Zhang Y, Liu Y, Zhou K, Zhang H.   +15 more
europepmc   +1 more source

Current status and future perspectives of platelet function‐guided precision antiplatelet therapy for patients with cerebral infarction

Neuroprotection, EarlyView.
Antiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Guoliang Zhu, Xiaoling Chen, Xinyi Huang, Quandan Tan, Qing Cao, Yali Yang, Yapeng Lin, Jie Yang   +7 more
wiley   +1 more source

Ultrafast Random Number Generation Using Broadband Polarization Chaos in QD Spin-VCSELs. [PDF]

Sensors (Basel)
Tselios C, Georgiou P, Politi CT, Alexandropoulos D.   +3 more
europepmc   +1 more source

Oral GLP‐1RA TERN‐601 for Adults With Obesity/Overweight: Placebo‐Controlled, Multiple‐Ascending‐Dose, Phase 1 and 2 Studies

Obesity, EarlyView.
ABSTRACT Objective The safety, tolerability, pharmacokinetics, and efficacy of TERN‐601, a once‐daily, oral small‐molecule glucagon‐like peptide‐1 (GLP‐1) receptor agonist, were studied in Phase 1 and 2 clinical studies. Methods The Phase 1 (28‐day) and Phase 2 (12‐week), randomized, double‐blind, placebo‐controlled, multiple‐ascending‐dose studies ...
W. Timothy Garvey, Julio Rosenstock, Harold E. Bays, Douglas Denham, Anita Kohli, Melanie Haines, Christopher Jones, Ellen Kwan, Erin Castelloe, Tonya Marmon, Emil Kuriakose, Cara Nelson   +11 more
wiley   +1 more source

A targeted combination therapy achieves effective pancreatic cancer regression and prevents tumor resistance. [PDF]

Proc Natl Acad Sci U S A
Liaki V, Barrambana S, Kostopoulou M, Lechuga CG, Zamorano-Dominguez E, Acosta-Gallego D, Morales-Cacho L, Álvarez R, Sun P, Rosas-Perez B, Barrero R, Jiménez-Parrado S, López-García A, San Roman M, López-Gil JC, Drosten M, Sainz B, Musteanu M, Caleiras E, Dusetti N, Poli V, Sánchez-Bueno F, Guerra C, Barbacid M.   +23 more
europepmc   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

Pediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia, Jie Zheng, Meng Yuan, Hongbo He, Yibo Fan, Bin Wang, Guanghua Zhu, Jun Yang, Yanhui Luo, Lixiao Cai, Pan Zhang, Yanlong Duan, Maoquan Qin   +12 more
wiley   +1 more source

Efficacy and Safety of SPH3127 Tablet, a Novel Direct Renin Inhibitor, in Patients with Mild-to-Moderate Essential Hypertension: A Phase III Randomised Trial. [PDF]

Drugs
Lv Q, Ma C, Wang F, Li L, Xiong G, Li Z, Qu Y, Pang W, Xiao W, Ruan H, Wei L, Liu G, Zhang J, Liu Q, Lin L, Long M, Li H, Yuan H, Liu L, Gao Y, Liu P, Zhang C, Wang Z, Xie J, Wang J, Zhang X, Lu Y, Huang K, Liu M, Chen J, Gao X, Wang D, Ma X, Chen X, Li Y, Zhang Y, Kong X, Chen F, Zhang X, Qi J, Cao Y, Huang Y, Zhang Y, Cui W.   +43 more
europepmc   +1 more source

Synthesis and application of alginate@CuFe2O4 polymeric spheres in 17‐β‐estradiol adsorption processes in Amazonian rivers

Polymer International, EarlyView.
Magnetic alginate beads, functionalized with copper ferrite, effectively remove 17‐β‐estradiol from Amazonian water, exhibiting optimized 238.65 μg g−1 capacity, fast 40 min kinetics, easy recovery, and successful remediation. Abstract The presence of endocrine‐disrupting compounds, such as 17‐β‐estradiol, in aquatic ecosystems poses a significant ...
Dante S Silva, Adriano R. S Silva, Yasmin S Medeiros, José R Santos Neto, Jamily L dos Santos, Ananias L dos Santos, Roberta L. S Bernardino, Giulian César S Sá, Leandro A Pocrifka, Sidnei C dos Santos, Emilly C Silva   +10 more
wiley   +1 more source