Results 11 to 20 of about 63,596 (104)

Screening of Drosophila microRNA-degradation sequences reveals Argonaute1 mRNA’s role in regulating miR-999

open access: yesNature Communications, 2023
MicroRNAs (miRNA) load onto AGO proteins to target mRNAs for translational repression or degradation. However, miRNA degradation can be triggered when extensively base-paired with target RNAs, which induces confirmational change of AGO and recruitment of
Peike Sheng   +8 more
semanticscholar   +1 more source

First-in-Human Study of OBI-999, a Globo H-Targeting Antibody-Drug Conjugate, in Patients With Advanced Solid Tumors

open access: yesJCO Precision Oncology, 2023
PURPOSE OBI-999 is a novel antibody-drug conjugate comprising the Globo H–targeting antibody (OBI-888) linked to the cytotoxic payload monomethyl auristatin E.
A. Tsimberidou   +5 more
semanticscholar   +1 more source

A qualitative analysis of stressors affecting 999 ambulance call handlers' mental health and well-being

open access: yesInternational Journal of Emergency Services, 2022
PurposeThe 999 ambulance call handler is critical in responding to emergency patient treatment; however, the call handlers are often a hidden component of the healthcare workforce and an under-researched group.
C. Powell   +4 more
semanticscholar   +1 more source

Effect of the use of an endotracheal tube and stylet versus an endotracheal tube alone on first-attempt intubation success: a multicentre, randomised clinical trial in 999 patients

open access: yesIntensive Care Medicine, 2021
The effect of the routine use of a stylet during tracheal intubation on first-attempt intubation success is unclear. We hypothesised that the first-attempt intubation success rate would be higher with tracheal tube + stylet than with tracheal tube alone.
Samir Jaber   +94 more
semanticscholar   +1 more source

International fisheries threaten globally endangered sharks in the Eastern Tropical Pacific Ocean: the case of the Fu Yuan Yu Leng 999 reefer vessel seized within the Galápagos Marine Reserve

open access: yesScientific Reports, 2021
Shark fishing, driven by the fin trade, is the primary cause of global shark population declines. Here, we present a case study that exemplifies how industrial fisheries are likely depleting shark populations in the Eastern Tropical Pacific Ocean.
Elisa Bonaccorso   +16 more
semanticscholar   +1 more source

Preclinical Studies of OBI-999: A Novel Globo H–Targeting Antibody–Drug Conjugate

open access: yesMolecular Cancer Therapeutics, 2021
Globo H (GH), a hexasaccharide, is expressed at low levels in normal tissues but is highly expressed in multiple cancer types, rendering it a promising target for cancer immunotherapy.
Ming-Chen Yang   +13 more
semanticscholar   +1 more source

The Usefulness of Spectral Mammography in Surgical Planning of Breast Cancer Treatment—Analysis of 999 Patients with Primary Operable Breast Cancer

open access: yesCurrent Oncology, 2021
Contrast-enhanced spectral mammography (CESM) is a promising, digital breast imaging method for planning surgeries. The study aimed at comparing digital mammography (MG) with CESM as predictive factors in visualizing multifocal-multicentric cancers ...
Andrzej J Lorek   +9 more
semanticscholar   +1 more source

SimLex-999: Evaluating Semantic Models With (Genuine) Similarity Estimation [PDF]

open access: yesInternational Conference on Computational Logic, 2014
We present SimLex-999, a gold standard resource for evaluating distributional semantic models that improves on existing resources in several important ways.
Felix Hill, Roi Reichart, A. Korhonen
semanticscholar   +1 more source

Redesign of facility layout to reduce the production line distance in MSE Silver 999 Malang

open access: yes, 2021
To be able to compete, every micro and small enterprises (MSE) must continue to innovate in both product and production process innovation. Silver 999 is MSE which produces jewellery from gold, silver, brass and other raw materials.
Mochammad Rofieq   +3 more
semanticscholar   +1 more source

XHate-999: Analyzing and Detecting Abusive Language Across Domains and Languages

open access: yesInternational Conference on Computational Linguistics, 2020
We present XHate-999, a multi-domain and multilingual evaluation data set for abusive language detection. By aligning test instances across six typologically diverse languages, XHate-999 for the first time allows for disentanglement of the domain ...
Goran Glavas, Mladen Karan, Ivan Vulic
semanticscholar   +1 more source

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