Results 11 to 20 of about 615,894 (105)

Validation of QF-PCR for prenatal diagnoses in a Brazilian population. [PDF]

Clinics (Sao Paulo), 2017
OBJECTIVES: Quantitative fluorescence polymerase chain reaction (QF-PCR) is a rapid and reliable method for screening aneuploidies, but in Brazil, it is not used in public services.
de Moraes RW, de Carvalho MHB, de Amorim-Filho AG, Francisco RPV, Romão RM, Levi JE, Zugaib M.   +6 more
europepmc   +3 more sources

The Contribution of QF-PCR and Pathology Studies in the Diagnosis of Diandric Triploidy/Partial Mole. [PDF]

Diagnostics (Basel), 2021
Objective: the aim of our study was to assess the contribution of quantitative fluorescent polymerase chain reaction (QF-PCR) and pathology studies in the diagnosis of diandric triploidies/partial hydatidiform moles.
Benítez L, Pauta M, Badenas C, Madrigal I, Nadal A, Marimon E, Borrell A.   +6 more
europepmc   +2 more sources

Comparison of the combined use of CNV-seq and karyotyping or QF-PCR in prenatal diagnosis: a retrospective study. [PDF]

Sci Rep, 2023
To elevate the accuracy of diagnostic results, CNV-seq is usually performed simultaneously with karyotyping or QF-PCR. Although several studies have investigated the performance of the combined use of CNV-seq with karyotyping or QF-PCR, there have been ...
Zhang H, Xu Z, Chen Q, Chen H, Ding X, Liu L, Xiao Y.   +6 more
europepmc   +2 more sources

Cytogenetic Analysis of Sporadic First-Trimester Miscarriage Specimens Using Karyotyping and QF-PCR: A Retrospective Romanian Cohort Study. [PDF]

Genes (Basel), 2022
It is well known that first-trimester miscarriages are associated with chromosome abnormalities, with numerical chromosome abnormalities being the ones most commonly detected. Conventional karyotyping is still considered the gold standard in the analysis
Popescu-Hobeanu G, Riza AL, Streață I, Tudorache Ș, Comănescu A, Tănase F, Drăgușin RC, Pascu C, Dijmărescu AL, Cara ML, Dorobanțu Ș, Petre-Mandache B, Cucu M, Sosoi SS, Ioana M, Iliescu D, Burada F.   +16 more
europepmc   +2 more sources

Comparison of conventional karyotype analysis and CMA results with ultrasound findings in pregnancies with normal QF-PCR results. [PDF]

Turk J Obstet Gynecol
Objective: In cases requiring fetal diagnostic testing, conventional karyotype analysis is initially preferred. However, quantitative fluorescent-polymerase chain reaction (QF-PCR) or fluorescent in situ hybridization methods are used alongside ...
Bütün Z, Kayapınar M, Şenol G, Akca E, Erzurumluoğlu Gökalp E, Artan S.   +5 more
europepmc   +2 more sources

Combination of QF-PCR and aCGH is an efficient diagnostic strategy for the detection of chromosome aberrations in recurrent miscarriage. [PDF]

Mol Genet Genomic Med, 2019
BACKGROUND: Our aim was to conduct a comprehensive genetic evaluation using the combination of QF-PCR (quantitative fluorescence polymerase chain reaction) and aCGH (array comparative genomic hybridization) for the detection of the frequency and type
Lovrečić L, Pereza N, Jaklič H, Ostojić S, Peterlin B.   +4 more
europepmc   +2 more sources

Multilevel regression modeling for aneuploidy classification and physical separation of maternal cell contamination facilitates the QF-PCR based analysis of common fetal aneuploidies. [PDF]

PLoS One, 2019
BackgroundThe quantitative fluorescent polymerase chain reaction (QF-PCR) has proven to be a reliable method for detection of common fetal chromosomal aneuploidies.
Noveski P, Terzic M, Vujovic M, Kuzmanovska M, Sukarova Stefanovska E, Plaseska-Karanfilska D.   +5 more
europepmc   +2 more sources

The consanguinity effect on QF‐PCR diagnosis of autosomal anomalies [PDF]

, 2015
Objectives Quantitative Fluorescent PCR (QF-PCR) is a simpler and faster method of detecting common chromosomal abnormalities when compared to cytogenetic analysis.
Zalloua, Pierre, Makhoul, Nadine, Mattar, Farid, Eid, Raymond, Zreik, Tony, Choueiri, Michel, Mroueh, Adnan   +6 more
core   +1 more source

Effective detection of 148 cases chromosomal mosaicism by karyotyping, chromosomal microarray analysis and QF-PCR in 32,967 prenatal diagnoses. [PDF]

BMC Med Genomics
Background Detection of mosaicism has always been difficult in prenatal diagnosis, which is to assess the value of karyotyping combined with three different molecular genetic tests for prenatal diagnosis. Retrospective review of chromosomal mosaicism (CM)
Deng Y, Zeng L, Wu Z, Wang J, Ye M, Chen C, Wei P, Wang D, Deng G, Zhu S.   +9 more
europepmc   +2 more sources

ANTENATAL DETECTION OF CHROMOSOMAL ABNORMALITIES COMBINING QF-PCR AND CYTOGENETIC ANALYSIS

, 2020
Aim: To compare the diagnostic values and limitations of quantitative fluorescent polymerase chain reaction (QF-PCR) and conventional cytogenetic analysis in prenatal diagnosis of chromosomal abnormalities.
Romana Gjergja-Juraski, Vedrana Skaro, Skaro, Vedrana, Ana Vicic, Petar Projic, Petra Korac, Korac, Petra, Feodora Stipoljev, Gjergja-Juraski, Romana, Vicic, Ana, Stipoljev, Feodora, Projic, Petar   +11 more
core   +1 more source