Results 51 to 60 of about 5,809 (168)

Pangenome analysis reveals the genetic mechanism underlying high‐altitude adaptation in Qinghai–Xizang (Tibet) Plateau Rhododendron

open access: yesJournal of Integrative Plant Biology, EarlyView.
Pan‐genome analysis reveals that high‐altitude Rhododendron species resist alpine cold stress by rapidly sensing and engaging the chilling response pathway and genes that directly and indirectly protect the plant from UV radiation. Heritable genomic features such as long terminal repeats contribute to the adaptive diversification of Rhododendron ...
Haoyang Zhou   +11 more
wiley   +1 more source

Mapping and Functional Characterization of Homologous Genes AhSUCA06 and AhSUCA16 Underlying Sucrose, Oil and Protein Contents in Peanut (Arachis hypogaea L.)

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Cultivated peanut (Arachis hypogaea L.) is an important oilseed and cash crop, and seed sucrose content (SSC), seed oil content (SOC) and seed protein content (SPC) are key determinants of seed flavour, texture, and overall quality. Identifying quantitative trait loci (QTLs) and candidate genes associated with SSC, SOC and SPC is therefore of ...
Yuzhen Zheng   +20 more
wiley   +1 more source

Evaluating putative lncRNA‐mediated ceRNA regulatory network involving miR396 and miR319 in maize leaf growth under Fusarium verticillioides infection

open access: yesAnnals of Applied Biology, Volume 189, Issue 1, July 2026.
The final leaf length of maize (Zea mays) was reduced due to the pathogenic fungus Fusarium verticillioides infection as a result of increased expression of miR396 in the elongation zone and decreased expression of miR319 in the mature zone of maize leaves, leading to antagonistic regulation of the expression of the GRF15 and TCP38, respectively ...
Erdem Emre Deligoz, Fatma Aydinoglu
wiley   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

open access: yesAdvanced Science, Volume 13, Issue 35, 24 June 2026.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li   +12 more
wiley   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

QF-PCR as a molecular-based method for autosomal aneuploidies detection

open access: yesAdvances in Reproductive Sciences, 2013
Objectives: The currently available methods for rapid prenatal diagnosis of common chromosomal aneuploidies are either Interphase-Fluorescence in Situ Hybridisation (I-FISH) or Quanti- tative Fluorescent Polymerase Chain Reaction (QF-PCR). QF-PCR represents a rapid, high throughput, cost-effective alternative for Interphase-FISH.
Reham Moftah   +6 more
openaire   +2 more sources

Prenatal diagnosis of mosaic trisomy 8: Clinical report and literature review

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2011
Objective: To present prenatal diagnosis of mosaic trisomy 8 and to review the literature. Materials, Methods, and Results: A 34-year-old woman underwent amniocentesis at 16 weeks of gestation because of advanced maternal age.
Chih-Ping Chen   +7 more
doaj   +1 more source

Genetic analysis of chorionic villus tissues in early missed abortions

open access: yesScientific Reports, 2023
Chromosomal abnormalities are the most common etiology of early spontaneous miscarriage. However, traditional karyotyping of chorionic villus samples (CVSs) is limited by cell culture and its low resolution.
Huili Xue   +5 more
doaj   +1 more source

The expected utility and psychological impacts of exome sequencing results in the DDD‐Africa study

open access: yesJournal of Genetic Counseling, Volume 35, Issue 3, June 2026.
Abstract Exome sequencing (ES) has become a valuable approach for diagnosing developmental disorders (DD), improving the diagnostic yield to up to 40%, and offering a potential end to the diagnostic odyssey experienced by many families. However, there remains a scarcity of studies assessing the lived experiences of parents and caregivers of individuals
Samantha Schnell   +11 more
wiley   +1 more source

Cytogenetic discrepancy between uncultured amniocytes and cultured amniocytes in mosaic trisomy 15 at amniocentesis

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2020
Objective: We present mosaic trisomy 15 at amniocentesis. Materials and methods: A 41-year-old woman underwent amniocentesis at 16 weeks of gestation because of an abnormal non-invasive prenatal testing (NIPT) result suspicious of trisomy 15 ...
Chih-Ping Chen   +10 more
doaj   +1 more source

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