Results 41 to 50 of about 536,981 (86)

Personalized pathology test for Cardio-vascular disease: Approximate Bayesian computation with discriminative summary statistics learning.

open access: yesPLoS Computational Biology, 2022
Cardio/cerebrovascular diseases (CVD) have become one of the major health issue in our societies. But recent studies show that the present pathology tests to detect CVD are ineffectual as they do not consider different stages of platelet activation or ...
Ritabrata Dutta   +8 more
doaj   +1 more source

EBSCO Library of Congress Classification Report 2009 [PDF]

open access: yes, 2009
This report lists all periodicals subscribed to in 2009 through EBSCO Subscription Services by the University Libraries, University of Rhode Island.

core   +1 more source

Transcriptional Differences between Normal and Glioma-Derived Glial Progenitor Cells Identify a Core Set of Dysregulated Genes

open access: yesCell Reports, 2013
Glial progenitor cells (GPCs) are a potential source of malignant gliomas. We used A2B5-based sorting to extract tumorigenic GPCs from human gliomas spanning World Health Organization grades II–IV.
Romane M. Auvergne   +14 more
doaj   +1 more source

Examination of hepato-renal functions and lipid panel among pregnant women with preeclampsia in Sétif, Algeria

open access: yesJournal of Biological Research, 2020
Preeclampsia (PE) is a multisystem pregnancy disease inflecting maternal, fetal mortality and morbidity. This case-control study aims to determine the biochemical changes in lipid profile, hepatic and renal functions among sixty preeclamptic women ...
Romyla Bourouba
doaj   +1 more source

Bayesian inference of ancestral recombination graphs.

open access: yesPLoS Computational Biology, 2022
We present a novel algorithm, implemented in the software ARGinfer, for probabilistic inference of the Ancestral Recombination Graph under the Coalescent with Recombination.
Ali Mahmoudi   +4 more
doaj   +1 more source

Lgr5+ve Stem/Progenitor Cells Contribute to Nephron Formation during Kidney Development

open access: yesCell Reports, 2012
Multipotent stem cells and their lineage-restricted progeny drive nephron formation within the developing kidney. Here, we document expression of the adult stem cell marker Lgr5 in the developing kidney and assess the stem/progenitor identity of Lgr5+ve ...
Nick Barker   +13 more
doaj   +1 more source

Urgent need for consistent standards in functional enrichment analysis.

open access: yesPLoS Computational Biology, 2022
Gene set enrichment tests (a.k.a. functional enrichment analysis) are among the most frequently used methods in computational biology. Despite this popularity, there are concerns that these methods are being applied incorrectly and the results of some ...
Kaumadi Wijesooriya   +4 more
doaj   +1 more source

High-Resolution Enzymatic Mapping of Genomic 5-Hydroxymethylcytosine in Mouse Embryonic Stem Cells

open access: yesCell Reports, 2013
We describe the use of a unique DNA-modification-dependent restriction endonuclease AbaSI coupled with sequencing (Aba-seq) to map high-resolution hydroxymethylome of mouse E14 embryonic stem cells. The specificity of AbaSI enables sensitive detection of
Zhiyi Sun   +11 more
doaj   +1 more source

The impact of the spatial heterogeneity of resistant cells and fibroblasts on treatment response.

open access: yesPLoS Computational Biology, 2022
A long-standing practice in the treatment of cancer is that of hitting hard with the maximum tolerated dose to eradicate tumors. This continuous therapy, however, selects for resistant cells, leading to the failure of the treatment.
Masud M A   +3 more
doaj   +1 more source

ATP4a Is Required for Wnt-Dependent Foxj1 Expression and Leftward Flow in Xenopus Left-Right Development

open access: yesCell Reports, 2012
Most vertebrate embryos break symmetry by a cilia-driven leftward flow during neurulation. In the frog Xenopus asymmetric expression of the ion pump ATP4a was reported at the 4-cell stage.
Peter Walentek   +4 more
doaj   +1 more source

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