Results 31 to 40 of about 7,990 (52)

Polylysine complexes and their biomedical applications

Engineered Regeneration, 2023
Poly-L-lysine (PLL) is a water-soluble biopolymer consist of repeating unit of L-lysine. It displays intrinsic non-antigenicity, antibacterial property, biocompatibility, and biodegradability, and facile synthesis procedure, therefore has attracted ...
Haofang Zhu, Rui Liu, Yixuan Shang, Lingyun Sun   +3 more
doaj   +1 more source

Breathable, stretchable and adhesive nanofibrous hydrogels as wound dressing materials

Engineered Regeneration, 2021
In spite of the great progress of wound healing materials, the development of dressing with moisture permeability, stretchable capability, and adhesive performance remains a huge challenge.
Xueting Liu, Yumin Liu, Jingtao Du, Xiaoran Li, Jianyong Yu, Bin Ding   +5 more
doaj   +1 more source

Polyhydroxyalkanoates in tissue repair and regeneration

Engineered Regeneration, 2022
Developing advanced biocompatibility materials is of critical importance in biomedical engineering. Polyhydroxyalkanoates (PHA), being famous for its flexible mechanical properties, thermal properties, biocompatibility, and biodegradability, has been ...
Wentai Guo, Keli Yang, Xiusen Qin, Rui Luo, Hui Wang, Rongkang Huang   +5 more
doaj   +1 more source

Photosensitizers with Aggregation-induced Emission and Their Biomedical Applications

Engineered Regeneration, 2022
Microorganisms and cancer have always been the fierce enemies of human beings, but the traditional methods of treating them still have many defects. Therefore, it is extremely important to develop rapid, effective and safe treatments.
Luojia Chen, Xingran Wang, Yuncong Yuan, Rui Hu, Qingrong Chen, Lijun Zhu, Meijia Gu, Chao Shen   +7 more
doaj   +1 more source

Bis-5HT modified Paris Saponin II nanoparticles treat neutrophil infiltrating allergic rhinitis by regulating the alanine metabolism pathway

Engineered Regeneration
Allergic rhinitis (AR) has emerged as a global concern, particularly due to the recent rise in disease incidence. There is an urgent need for safer, more effective, and shorter-term targeted immunotherapy approaches.
Wenwen Qi, Lei Shi, Xinhao Wu, Fangyuan Zhu, Zhenxiao Teng, Xiaochen Gao, Xin Bing, Na Guo, Xue Cao, Chengzhilin Li, Houyang Hu, Fanyu Yuan, Yuhan Dong, Ming Xia, Chengcheng Liu   +14 more
doaj   +1 more source

Novel injectable composite incorporating denosumab promotes bone regeneration via bone homeostasis regulation

Engineered Regeneration
Repair of large bone defects remains to be clinically challenging, yet current bone repair strategies focus on optimizing the osteogenic capacity of bone grafts, while the role of osteoclasts in bone regeneration has been largely ignored.
Guang Yang, Zili Guo, Xiangfeng Zhang, Jiayu Chen, Jie Weng, Jiapeng Bao, Xiaohua Yu   +6 more
doaj   +1 more source

Targeted delivery of factors and cells for improving cardiac tissue regeneration and heart function following myocardial infarction

Engineered Regeneration
Following myocardial infarction (MI), cardiac tissue undergoes irreversible cellular alterations, with cardiomyocytes being replaced by fibrotic tissue. In order to improve tissue regeneration, a previously characterized chitosan-based cryogel, which was
Kamila Raziyeva, Zharylkasyn Zharkinbekov, Yevgeniy Kim, Arman Saparov   +3 more
doaj   +1 more source

LSM6 promotes cell proliferation and migration regulated by HMGB1 in laryngeal squamous cell carcinoma

Engineered Regeneration
Elevated levels of high mobility group protein B1 (HMGB1) play a significant role in the pathogenesis of many diseases, but is particularly important for the formation of malignant tumors.
Dengbin Ma, Jiayi Li, Hui Li, Yao Tang, Xia Gao, Hong Chen, Xiaoyun Qian, Xiaohui Shen   +7 more
doaj   +1 more source

Flexible wearable sensors: An emerging platform for monitoring of bacterial infection in skin wounds

Engineered Regeneration
Persistent inflammatory responses often occur when bacteria and other microorganisms frequently invade and colonize open wounds and eventually result in the formation of chronic wounds.
Hao Meng, Weicheng Zhong, Kui Ma, Jianlong Su, Liqian Ma, Yaying Hao, Yufeng Jiang, Xi Liu, Xiaobing Fu, Cuiping Zhang   +9 more
doaj   +1 more source

Suppression of NFATc1 through NF-kB/PI3K signaling pathway by Oleandrin to inhibit osteoclastogenesis and bone resorption

Engineered Regeneration
Inflammation can initiate osteolysis, which is the breakdown of bone by fully developed osteoclasts. The compound Oleandrin is recognized for its effects against inflammation and tumors.
Zhikun Li, Kai Chen, Qifeng Yu, Yifan Li, Shichao Tong, Ruijun Xu, Ruixi Hu, Yi Zhang, Wei Xu   +8 more
doaj   +1 more source