Results 1 to 10 of about 504 (110)

Totality of evidence of the effectiveness of repurposed therapies for COVID‐19: Can we use real‐world studies alongside randomized controlled trials? [PDF]

Clinical and Translational Science, 2023
Rapid and robust strategies to evaluate the efficacy and effectiveness of novel and existing pharmacotherapeutic interventions (repurposed treatments) in future pandemics are required. Observational “real‐world studies” (RWS) can report more quickly than
Jaap Mandema, Hugh Montgomery, Louis Dron, Shuai Fu, Estelle Russek‐Cohen, Christina Bromley, Samer Mouksassi, Amy Lalonde, Aaron Springford, Larry Tsai, Phil Ambery, Doug McNair, Nawab Qizilbash, Stuart Pocock, Névine Zariffa   +14 more
doaj   +3 more sources

A Prospective Open‐Label Observational Study of a Buffered Soluble 70 mg Alendronate Effervescent Tablet on Upper Gastrointestinal Safety and Medication Errors: The GastroPASS Study [PDF]

JBMR Plus, 2021
Upper gastrointestinal (GI) side effects are a main reason for discontinuing bisphosphonate treatment, an important therapeutic option for osteoporosis patients. Consequently, the development of novel formulations with improved tolerability is warranted.
Salvatore Minisola, Antonio P Vargas, Giulia Letizia Mauro, Fernando Bonet Madurga, Giovanni Adami, Dennis M Black, Nawab Qizilbash, Josep Blanch‐Rubió   +7 more
doaj   +3 more sources

Malignancy rates in Crohn's disease patients with perianal fistula: A German retrospective cohort study. [PDF]

United European Gastroenterol J, 2023
Abstract Background Patients with inflammatory bowel disease are at increased risk of colorectal and extra‐intestinal cancer. However, the overall cancer risk in patients with Crohn's disease (CD) with perianal fistulas (PF) (CPF) and those with CD without PF (non‐PF CD) is unclear.
Podmore B, Beier D, Burisch J, Genestin E, Haeckl D, Nagel O, Qizilbash N, Schwartz DA, Vavricka SR, Bennett D, Dignass A.   +10 more
europepmc   +2 more sources

Real world safety of methoxyflurane analgesia in the emergency setting: a comparative hybrid prospective-retrospective post-authorisation safety study [PDF]

BMC Emergency Medicine, 2023
Background Low-dose analgesic methoxyflurane (Penthrox®) was approved in Europe for emergency relief of moderate to severe pain in conscious adults with trauma in 2015. A comparative post-authorisation safety study (PASS) was conducted to assess the risk
Nawab Qizilbash, Himanshu Kataria, Heather Jarman, Ben Bloom, Michelle Bradney, Maggie Oh, Sue Anne Yee, Ana Roncero, Ignacio Mendez, Stuart Pocock   +9 more
doaj   +2 more sources

Incidence of pneumococcal disease from 2003 to 2019 in children ≤17 years in England [PDF]

Pneumonia, 2023
Background Pneumococcal disease is a leading cause of communicable disease morbidity and mortality globally. We aimed to estimate invasive pneumococcal disease (IPD), pneumococcal pneumonia (PP) and all-cause pneumonia (ACP) incidence rates (IRs) in ...
Salini Mohanty, Bélène Podmore, Ana Cuñado Moral, Ian Matthews, Eric Sarpong, Alessandra Lacetera, Nawab Qizilbash   +6 more
doaj   +2 more sources

Healthcare resource utilisation and cost of pneumococcal disease from 2003 to 2019 in children ≤17 years in England. [PDF]

PLoS ONE, 2023
ObjectiveTo estimate healthcare resource utilisation (HCRU) and costs associated with pneumococcal disease (PD) in children aged ≤17 years in England from 2003-2019.MethodsA retrospective study in children aged ≤17 years was conducted using the Clinical ...
Salini Mohanty, Bélène Podmore, Ana Cuñado Moral, Ian Matthews, Eric Sarpong, Agueda Azpeitia, Nawab Qizilbash   +6 more
doaj   +2 more sources

Thymoquinone-Enriched Naringenin-Loaded Nanostructured Lipid Carrier for Brain Delivery via Nasal Route: In Vitro Prospect and In Vivo Therapeutic Efficacy for the Treatment of Depression [PDF]

Pharmaceutics, 2022
In the current research, a thymoquinone-enriched naringenin (NGN)-loaded nanostructured lipid carrier (NLC) was developed and delivered via the nasal route for depression.
Farheen Fatima Qizilbash, Muhammad Usama Ashhar, Ameeduzzafar Zafar, Zufika Qamar, Annu, Javed Ali, Sanjula Baboota, Mohammed M. Ghoneim, Sultan Alshehri, Asgar Ali   +9 more
doaj   +2 more sources

Healthcare resource utilization and cost of pneumococcal disease in children in Germany, 2014–2019: a retrospective cohort study [PDF]

Pneumonia, 2023
Background Since the introduction of higher valency pneumococcal conjugate vaccines in 2009, recent estimates on the economic burden of pediatric pneumococcal disease (PD) in Germany have been lacking. This study estimates healthcare resource utilization
Tianyan Hu, Bélène Podmore, Rosemarie Barnett, Dominik Beier, Wolfgang Galetzka, Nawab Qizilbash, Dennis Heckl, Timo Boellinger, Jessica Weaver   +8 more
doaj   +2 more sources

Incidence of acute otitis media from 2003 to 2019 in children ≤ 17 years in England [PDF]

BMC Public Health, 2023
Background The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in 2006 and the 13-valent pneumococcal conjugate vaccine (PCV13) in 2010 in the UK.
Salini Mohanty, Bélène Podmore, Ana Cuñado Moral, Thomas Weiss, Ian Matthews, Eric Sarpong, Ignacio Méndez, Nawab Qizilbash   +7 more
doaj   +2 more sources

Correlation between Body Mass Index and Cognitive Function in Patients with Atrial Fibrillation. [PDF]

J Interv Cardiol, 2022
Background. Evidence regarding the relationship between body mass index (BMI) and cognitive function was limited. Therefore, the objective of this research is to investigate whether BMI is independently related to cognitive function in Chinese patients with atrial fibrillation after adjusting for other covariates. Methods.
Guo L, Yin P, Li X, Wang X, Xue J, Wang W, Song D, Xu G, Shang M, Liu S, Chen Y, Zhang Q, Sun D.   +12 more
europepmc   +2 more sources