Results 11 to 20 of about 109,660 (100)
Current treatment for patients with metastatic hormone-sensitive prostate cancer (mHSPC) delays disease progression and improves survival, but resistance is inevitable. Additional therapies that prolong survival are needed.
C. Gratzke+8 more
semanticscholar +1 more source
Pharmacological AMPK activation represents an attractive approach for the treatment of type 2 diabetes (T2D). AMPK activation increases skeletal muscle glucose uptake, but there is controversy as to whether AMPK activation also inhibits hepatic glucose ...
M. Johanns+13 more
semanticscholar +1 more source
Alzheimer’s disease (AD) is a neurodegenerative disorder that represents the first cause of dementia. Although there has been significant progress in AD research, the actual mechanisms underlying this pathology remain largely unknown. There is increasing
S. Piccirillo+6 more
semanticscholar +1 more source
Background Sarcoma of the breast is a rare malignancy with heterogeneous histology. Angiosarcoma, including secondary angiosarcoma from previous radiation, is the most common type of sarcoma of the breast.
J. S. Lee, K. Yoon, M. Onyshchenko
semanticscholar +1 more source
DFNA5 (GSDME) c.991-15_991-13delTTC: Founder Mutation or Mutational Hotspot?
Deafness due to mutations in the DFNA5 gene is caused by the aberrant splicing of exon 8, which results in a constitutively active truncated protein. In a large family of European descent (MORL-ADF1) segregating autosomal dominant nonsyndromic hearing ...
K. Booth, H. Azaiez, Richard J. H. Smith
semanticscholar +1 more source
Introduction One of the biggest challenges facing students today is procrastination, which is closely related to stress, anxiety and, in the most severe cases, depression.
Antonio Ragusa+7 more
semanticscholar +1 more source
IMA–CNMNC approved mineral symbols
Several text symbol lists for common rock-forming minerals have been published over the last 40 years, but no internationally agreed standard has yet been established.
L. Warr
semanticscholar +1 more source
A regional-scale survey was conducted to assess the occurrence, distribution, and risk of two extensively used pesticides (organophosphate pesticides and pyrethroids) in agricultural soils from the Pearl River Delta (PRD), South China.
Runlin Yao+5 more
semanticscholar +1 more source
The earliest arbitration treaty? A reassessment of the Anglo-Norman treaty of 991*
Concluded at Rouen in March 991, the Anglo-Norman treaty has traditionally occupied a very small corner of the huge historiography for King AEthelred’s reign as one of the first of the king’s failures to deal with the threat of renewed viking raids. This
J. Benham
semanticscholar +1 more source
AMP-activated protein kinase (AMPK) plays diverse roles and coordinates complex metabolic pathways for maintenance of energy homeostasis. This could be explained by the fact that AMPK exists as multiple heterotrimer complexes comprising a catalytic α ...
L. Bultot+14 more
semanticscholar +1 more source