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Scalp dosimetry as a predictor of radiation-induced alopecia in primary brain tumours: a retrospective study from a tertiary cancer centre in south India

Journal of Current Oncology and Medical Sciences
Introduction: Radiotherapy is essential in treating primary brain tumours, but radiation-induced alopecia (RIA) remains a common side effect that significantly affects patients' quality of life (QOL). With its psychosocial impact on self-image, emotional
Lalitha Nageshwari S +6 more
doaj

Enhancing quality of mental health service for veterans with seizures

Epilepsia, EarlyView.
Abstract Psychiatric disorders are commonly identified in people with seizures (PWS). Comorbid mood, anxiety, and trauma‐ and stressor‐related disorders are highly prevalent and not consistently recognized or treated promptly. Veterans with seizures are particularly vulnerable to neuropsychiatric comorbidities, including a higher prevalence of ...
Maria Raquel Lopez +6 more
wiley +1 more source

Instrumental activities of daily living in older adults with epilepsy: A cross‐sectional and longitudinal multicenter study

Epilepsia, EarlyView.
Abstract Objective Instrumental activities of daily living (IADLs) represent a critical but understudied measure of day‐to‐day function in people with epilepsy (PWE). In the multicenter Brain Aging and Cognition in Epilepsy (BrACE) study of PWE ≥55 years of age, we examined the proportion, clinical correlates, epilepsy‐related predictors, and ...
Ifrah Zawar +17 more
wiley +1 more source

Beyond seizure control: Non–seizure‐related outcomes in focal‐onset epilepsy treated with adjunctive cenobamate. Third interim results from the BLESS study

Epilepsia, EarlyView.
Abstract Objective Cenobamate is approved for treatment of focal seizures in adults, but evidence on non‐seizure outcomes remains limited. This interim statistical analysis of the cenoBamate in aduLts with focal‐onsEt SeizureS (BLESS) study evaluated patient‐ and clinician‐reported outcomes for up to 52 weeks of cenobamate treatment.
Simona Lattanzi +206 more
wiley +1 more source

Fenfluramine treatment and seizure‐free days in pediatric and adult patients with Lennox–Gastaut syndrome: A post hoc analysis

Epilepsia, EarlyView.
This graphical abstract provides an overview of the post hoc analysis evaluating change in percentage of seizure‐free days in pediatric and adult patients treated with fenfluramine in the Lennox‐Gastaut syndrome phase 3 study. Abstract The most common primary endpoint for assessing treatment efficacy in patients with Lennox–Gastaut syndrome (LGS) is ...
Stéphane Auvin +8 more
wiley +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza +4 more
wiley +1 more source

Evaluating the impact of an AI‐powered chatbot on epilepsy education and stigma reduction: A pre‐post intervention study using EpiloBot

Epilepsia Open, EarlyView.
Abstract Objective Effective epilepsy management requires accurate epilepsy knowledge, active patient engagement, and stigma reduction to improve health outcomes. Educational interventions have been shown to enhance patients' quality of life (QOL) and knowledge. This study evaluated the effectiveness of EpiloBot, an artificial intelligence (AI)‐powered
Izumi Kuramochi +10 more
wiley +1 more source

Auditory gamma‐band synchronization and attentional performance in juvenile myoclonic epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Cognitive difficulties in juvenile myoclonic epilepsy (JME) are part of the clinical phenotype alongside epileptic seizures; however, the underlying neurophysiological mechanisms remain unclear. Auditory steady‐state responses (ASSRs) to repetitive 40‐ and 80‐Hz stimuli are widely used measures of gamma‐band oscillations (GBOs ...
Ryo Mitoma +12 more
wiley +1 more source

Silence around SUDEP and its impact on caregivers of individuals with developmental and epileptic encephalopathies: An international survey

Epilepsia Open, EarlyView.
Abstract Objective Sudden Unexpected Death in Epilepsy (SUDEP) is the leading cause of epilepsy‐related mortality, particularly in individuals with Developmental and Epileptic Encephalopathies (DEEs). The goal of this work is to assess SUDEP‐related knowledge, information practices, emotional and psychological impact, and the use of preventive measures
José Ángel Aibar +8 more
wiley +1 more source

Prepare, don't scare: Rethinking cognitive readiness before epilepsy surgery

Epilepsia Open, EarlyView.
Abstract Epilepsy surgery is an effective but underutilized treatment for drug‐resistant epilepsy, and concerns about postsurgical cognitive change are a prominent barrier. Refinements in surgical technique can reduce cognitive impact, but cognitive change cannot always be avoided, and approaches carrying lower cognitive risk are often less effective ...
Kayela Arrotta +3 more
wiley +1 more source

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