Results 131 to 140 of about 149,321 (265)

Pelvic Exenteration for Cervical Cancer: Oncological, Morbidity and Quality of Life Outcomes

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives One third of patients who undergo definitive chemoradiotherapy for locally advanced cervical cancer develop disease recurrence. Salvage surgery in the form of pelvic exenteration (PE) may offer improved survival and possibly cure in carefully selected patients, however robust data is scarce.
Alexandra M. Peacock, Kilian G.M. Brown, Peter J. M. Lee, Kirk K. S. Austin, Christopher M. Byrne, Daniel Steffens, Michael J. Solomon   +6 more
wiley   +1 more source

Association of Adjuvant Radiotherapy De‐Escalation With Outcomes Following Oncoplastic Breast‐Conserving Surgery

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Adjuvant radiotherapy (RT) following breast‐conserving surgery reduces local recurrence but can introduce reconstructive morbidity. Although recent trials support the safe omission of RT in selected patients, its impact on surgical and patient‐reported outcomes following oncoplastic breast‐conserving surgery (OPBCS) remains poorly ...
Abbas M. Hassan, Carson Park, Kathryn Borders, Rachel M. Danforth, Ravinder Bamba, R. Jason VonDerHaar, Ivan Hadad, Mary E. Lester, Carla S. Fisher, Aladdin H. Hassanein   +9 more
wiley   +1 more source

DERMACLEAR: AI‐Powered Insights Into Four Chronic Inflammatory Skin Diseases in Spain

JEADV Clinical Practice, EarlyView.
Using an AI‐enhanced analysis of electronic health records from nearly 50,000 patients, the DERMACLEAR study provides real‐world insights into the prevalence, clinical complexity, comorbidities and treatment patterns of HS, CU, PsO and AD in Spain.
Ana Giménez‐Arnau, Javier Ortiz de Frutos, Raquel Rivera‐Díaz, Lluís Puig, Jaume Notario Rosa, José Luis López‐Estebaranz, Vicente García‐Patos Briones, Ana Martín‐Santiago, José Ignacio Rojo‐Laguna, Elisabet Fernández‐Martínez, Lara Gómez‐Labrador, Esteban Daudén   +11 more
wiley   +1 more source

Validation of the Investigator's Global Assessment Scale for Epidermolysis Bullosa Simplex

JEADV Clinical Practice, EarlyView.
ABSTRACT Background There is a lack validated outcome measures to assess wound severity in epidermolysis bullosa simplex (EBS). Objectives To assess the reliability and validity of the Investigator's Global Assessment (IGA) scale and a newly developed palms/soles subscale through in‐clinic scoring and review of patient‐submitted photographs.
Pirunthan Pathmarajah, Shufeng Li, Maya B. Mathur, Joyce M. C. Teng, M. Peter Marinkovich, Austin N. Johnson, Shehla Admani, Edward Eid, Joanna Tu, Dominique C. Mitchell, Lila Perrone, Ricardo Villanueva Gaona, Jean Y. Tang, Albert S. Chiou   +13 more
wiley   +1 more source

Scale of Alopecia Areata Distress (SAAD‐41): Initial Validation Part 2—Scoring, Preliminary Reference Values and Validity

JEADV Clinical Practice, EarlyView.
The SAAD‐41 is a 41‐item scale developed to comprehensively assess Alopecia Areata psychosocial patient‐reported outcomes. Results support scoring the scale at the subdomain level and provisionally at the total‐score level. The total‐score can be calculated as a sum of the 41 SAAD items, with the sum referred to as the SAAD‐41‐Total.
Kristina Gorbatenko‐Roth, Mattea Trinitapoli, Sarah Wood, Irmina Wallander, Jaime Nugent, Maria Hordinsky   +5 more
wiley   +1 more source

Impact of BMI and Body Weight on Clinical Outcomes in Psoriasis: A Post Hoc Analysis of the RESOLVE Observational Study

JEADV Clinical Practice, EarlyView.
This post‐hoc analysis of the Greek real‐world ReSOLVE study compared clinical and patient‐reported outcomes by body weight (< 100 kg vs. ≥ 100 kg) and BMI over 52 weeks. Patients ≥ 100 kg showed delayed PASI and sPGA responses at W24 and W52, while BMI had little impact. Quality‐of‐life improvements were substantial, though early gains were smaller in
Pantelis Panagakis, Kanella Kalapothakou, Despina Exadactylou, Ioanna Lefaki, Marina Papoutsaki, Natalia Rompoti, Dimitrios Xekardakis, Nikolaos Fekkas, Efthymios Stathatos, Athanasios Chaniotis, Electra Nicolaidou, Alexandros Stratigos, Vasiliki Chasapi   +12 more
wiley   +1 more source

The Impact of Trait Mindfulness on Quality of Life in Patients With Bipolar Disorder: The Serial Mediating Role of Emotion Dysregulation and Depressive/Manic Symptoms. [PDF]

Actas Esp Psiquiatr
Xu Y.
europepmc   +1 more source

Quality of life and its associated factors among adult PLWHA on ART in Fako Division, South West Region of Cameroon. [PDF]

PLOS Ment Health
Nkanjo BM, Tambe AB, Ufuan AA, Movuh SD, Nicholas T.   +4 more
europepmc   +1 more source

Chronic Kidney Disease‐Associated Pruritus Is Linked to Selective Enrichment of Taurine‐Conjugated Bile Acid Subspecies

JEADV Clinical Practice, EarlyView.
Chronic kidney disease‐associated pruritus (CKDaP) is a frequent complication of advanced CKD with an incompletely understood pathophysiology. We identified a significantly altered glycine‐to‐taurine conjugated bile acid ratio in patients with CKDaP despite unchanged total serum bile acid concentrations.
Miriam M. Düll, Manfred Rauh, Peter Dietrich, Marcel Vetter, Jonas Schmid, Thomas Mettang, Andreas E. Kremer   +6 more
wiley   +1 more source

Development and preliminary validation of the Arabic Quality of Life During War Scale (AQOL-War). [PDF]

PLoS One
Hussein MF, Mohamed YY, Tolba B, Abdel-Rahman S, Abdel-Fattah MA, Elsheikh NG, Elkholy N, Gebreal A, Alshaikh AA, Modawy AYF, Alawad OA, Elbushra RBI, Ghazy RM.   +12 more
europepmc   +1 more source