Results 131 to 140 of about 31,446 (257)

Extracellular ionic concentration modulates arrhythmias in a simulated population of human ventricular myocytes with long QT syndrome type 3

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustrating the in silico study pipeline. A total of 50,000 virtual myocytes were generated, which were then filtered to 7093 myocytes that fit experimentally constrained biomarkers for physiological electrical and calcium behaviour under wild‐type conditions.
Katherine Flannery   +3 more
wiley   +1 more source

Two cases of wide QRS complex tachycardia caused by anamorelin. [PDF]

open access: yesJ Cardiol Cases, 2022
Okidono Y   +5 more
europepmc   +1 more source

Electrocardiographic Correlates of Myocardial Remodeling After Cardiac Resynchronization Therapy

open access: yes
Pacing and Clinical Electrophysiology, EarlyView.
Christian Toquica   +6 more
wiley   +1 more source

Longer action potential duration in the Purkinje network than in the ventricular myocardium delays retrograde activation of the human His‐Purkinje system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Activation time (AT) maps from right ventricular apical pacing in a human ventricles model with longer action potential duration in the His‐Purkinje system (HPS) than in the myocardium (MYO). For pacing with a long S1S2 coupling interval (CI), the AT from the myocardial pacing site to the first AT of the HPS (ATMYO) is longer ...
Jason D. Bayer   +3 more
wiley   +1 more source

High-frequency content within the QRS complex can predict ventricular tachyarrhythmias in hypertrophic cardiomyopathy. [PDF]

open access: yesJ Arrhythm
Tsutsumi T   +8 more
europepmc   +1 more source

Management of hemodynamically stable wide QRS complex tachycardia in patients with implantable cardioverter defibrillators. [PDF]

open access: yesFront Cardiovasc Med, 2022
Regoli FD   +8 more
europepmc   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato   +3 more
wiley   +1 more source

QRS 3D voltage-time integral in narrow QRS complex - Establishing the normal reference range. [PDF]

open access: yesJ Electrocardiol
Gupta A   +10 more
europepmc   +1 more source

hERG1 channels and potential therapeutics for long QT syndrome

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider   +3 more
wiley   +1 more source

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