Results 51 to 60 of about 144 (143)

Pharmacokinetics and safety of eptinezumab in children and adolescents with migraine

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The primary objective was to characterize the pharmacokinetics (PK) and safety of eptinezumab in children and adolescents with migraine. Background Migraine in children and adolescents is a prevalent and potentially debilitating disease, and few preventive therapies are approved for use in these populations. Eptinezumab, a calcitonin
Andrew D. Hershey, Johan Areberg, Line Pickering Boserup, Annika Lindsten, Monika Rosen   +4 more
wiley   +1 more source

Emergency Nurses' Perceptions and Experiences in Managing Acute Pain in Critically Ill Adult Patients: A Qualitative Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim The aim of this study was to examine the perceptions and experiences of emergency nurses managing acute pain in critically ill patients. Design Qualitative descriptive study. Method Non‐participant observations (n = 46, 157 h across 10 shifts) and semi‐structured interviews (n = 30) were conducted at two Australian metropolitan emergency ...
Wayne Varndell, Margaret Fry, Doug Elliott   +2 more
wiley   +1 more source

Catheter Ablation of Parahisian Premature Ventricular Complexes From the Right Sinus of Valsalva

Journal of Cardiovascular Electrophysiology, Volume 36, Issue 4, Page 731-738, April 2025.
ABSTRACT Background Cather ablation of parahisian premature ventricular complexes (PVCs) often requires ablation in multiple cardiac chambers, including the sinuses of Valsalva (SoV). The safety and efficacy of ablation within the right SoV to target parahisian arrhythmias has not been widely reported.
Michael Ghannam, Jamie Simpson, Mohamed Al‐Sadawi, Amrish Deshmukh, Jackson J. Liang, Rakesh Latchamsetty, Thomas Crawford, Krit Jongnarangsin, Hakan Oral, Frank Bogun   +9 more
wiley   +1 more source

Clinical Features of Brugada Syndrome Patients With SCN5A Variants

Journal of Cardiovascular Electrophysiology, EarlyView.
Longer r‐J interval in lead V1, fragmented QRS and carrying SCN5A variants other than benign variants are independently associated with the cardiac events in BrS patients. LAS40 and RMS40 are useful for the risk stratification in BrS patients with SCN5A VUS or pathogenic variants.
Sho Okamura, Hidenori Ochi, Mika Nakashima, Rie Akiyama, Takehito Tokuyama, Yousaku Okubo, Shunsuke Miyauchi, Shogo Miyamoto, Naoto Oguri, Yukimi Uotani, Takumi Sakai, Motoki Furutani, Yasuki Kihara, Yukiko Nakano   +13 more
wiley   +1 more source

Differences Between the Unipolar Versus Bipolar Potential‐Based Activation Maps of Ventricular Premature Contractions Arising From Ventricular Outflow Tracts

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background The use of an automated annotation algorithm based on the maximal negative derivative of the unipolar potential (−dV/dTmax) for local activation timing in the ablation of outflow tract (OT) ventricular premature contractions (VPCs) remains controversial.
Yoshimori J. An, Masafumi Sugawara, Jakub Sroubek, Katsuhide Hayashi, John O. Lopez, Justin Lee, Shady Nakhla, Pasquale Santangeli, Oussama M. Wazni, Koji Higuchi   +9 more
wiley   +1 more source

Comparison of Clinical Outcomes Between Left Bundle Branch Area Pacing With a Stylet‐Driven Lead and Conventional Right Ventricular Pacing

Journal of Cardiovascular Electrophysiology, EarlyView.
In this cohort study including 738 patients (243 left bundle branch area pacing using stylet‐driven lead vs. 495 right ventricular pacing), left bundle branch area pacing was associated with a lower risk of the primary outcome by 73% compared to right ventricular pacing with comparable safety profiles.
Kyung‐Yeon Lee, Jinsun Park, JungMin Choi, Hyo‐Jeong Ahn, Soonil Kwon, Myung‐Jin Cha, Jun Kim, Gi‐Byoung Nam, Kee‐Joon Choi, Eue‐Keun Choi, Seil Oh, Min Soo Cho, So‑Ryoung Lee   +12 more
wiley   +1 more source

Clinical Significance and Management of Atrioventricular Block Associated With Bradycardic/Antiarrhythmic Drug Therapy: Drug‐Induced or Drug‐Revealed?

Journal of Cardiovascular Electrophysiology, EarlyView.
Schematic representation of the management pathway in drug‐related advanced atrioventricular block. ABSTRACT The development of advanced atrioventricular block (AVB) in patients on bradycardic and/or antiarrhythmic therapy (drug‐related AVB) represents a clinical challenge, raising the question of whether the AVB is directly caused by these agents ...
Dimitrios Sfairopoulos, George Bazoukis, Skevos Sideris, Nikolaos Fragakis, Konstantinos Letsas, Konstantinos Zekios, Tong Liu, Panagiotis Korantzopoulos   +7 more
wiley   +1 more source

Clinical Phenotypes in Relation to Outcomes in Heart Failure Patients With Cardiac Resynchronization Therapy and Defibrillators (CRT‐D): An Unsupervised Cluster Analysis

Journal of Cardiovascular Electrophysiology, EarlyView.
Graphical abstract showing the 4 clusters identified in CRT‐D patients. Abstract Background Patients with heart failure undergoing cardiac resynchronization therapy (CRT) are a heterogenous and complex population. Objective To identify different clusters of patients with CRT‐D and to evaluate the associations with clinical outcomes, using cluster ...
Luigi Gerra, Tommaso Bucci, Arnaud Bisson, Alexandre Bodin, Bertrand Pierre, Giuseppe Boriani, Gregory Y. H. Lip, Laurent Fauchier   +7 more
wiley   +1 more source

Impact of Collaborative Nursing Care on Health Outcomes of Mental Health Day Hospital Users: A Mixed Methods Study

Journal of Psychiatric and Mental Health Nursing, Volume 32, Issue 3, Page 575-590, June 2025.
ABSTRACT Introduction Given that recovery‐oriented care focuses on empowering individuals with mental health challenges, collaborative care can be an effective tool for nurses in mental health day hospitals. Aim To deepen knowledge about the impact of collaborative nursing care for improving health outcomes of mental health day hospital users.
Ana Ventosa‐Ruiz, Antonio R. Moreno‐Poyato, Cristina Cañete‐Massé, Júlia Rolduà‐Ros, Isabel Feria‐Raposo, Karina Campoverde, Montserrat Puig Llobet   +6 more
wiley   +1 more source

Profiling the sleep architecture of ageing adults using a seven‐state continuous‐time Markov model

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is a complex biological process regulated by networks of neurons and environmental factors. As one falls asleep, neurotransmitters from sleep–wake regulating neurones work in synergy to control the switching of different sleep states throughout the night. As sleep disorders or underlying neuropathology can manifest as irregular switching,
Jonathon Jacobs, Caitlin E. Martin, Bernard Fuemmeler, Shanshan Chen   +3 more
wiley   +1 more source