Weaving New Smart Objects: Actuation and Sensing at a Single Electroactive Interface
ChemElectroChem, EarlyView.Electrochemical pH sensing and pH‐triggered release of a molecule simultaneously occur from the smart textile. A screen‐printed organic semiconductor is functionalized to obtain an electrochemically gated pH sensor. Following the optimized loading with a model molecule, the wearable device can perform quantitative pH sensing during pH‐controlled ...
Federica Mariani +4 more
wiley +1 more source
Antiarrhythmic effect of Vernakalant due to reduction of dispersion of repolarization and suppression of early afterdepolarizations in a rabbit model of acquired long-QT-syndrome [PDF]
, 2013 Peter Milberg +3 more
openalex +1 more source
A probabilistic diagnostic for Laplace approximations: Introduction and experimentation
Canadian Journal of Statistics, EarlyView.Abstract Many models require integrals of high‐dimensional functions: for instance, to obtain marginal likelihoods. Such integrals may be intractable, or too expensive to compute numerically. Instead, we can use the Laplace approximation (LA). The LA is exact if the function is proportional to a normal density; its effectiveness therefore depends on ...
Shaun McDonald, Dave Campbell
wiley +1 more source
QT dispersion: an indication of arrhythmia risk in patients with long QT intervals. [PDF]
, 1990 Christopher P. Day +2 more
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Clinical Pharmacology in Drug Development, EarlyView.Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams +7 more
wiley +1 more source
Can QT dispersion improve the accuracy of stress ECG TMT in detecting myocardial ischemia in chronic stable CAD patients? A stress myocardial perfusion imaging study. [PDF]
Egypt Heart J, 2021 Eltahlawi MA +3 more
europepmc +1 more source
Price Stickiness Asymmetry, Persistence and Volatility in a New Keynesian Model [PDF]
In a two-sector New-Keynesian model, this paper shows that the dispersion in the degree of sectoral price stickiness plays a key role in the determination of the dynamics of aggregate inflation and, consequently, of the whole economy.
Alessandro Flamini
core +1 more source
A16-6 Effect of carvedilol in the qt dispersion in patients with heart failure and the impact on the mortality [PDF]
, 2003 Jefferson Curimbaba
openalex +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi +11 more
wiley +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract The oral, small molecule inhibitor of activin receptor‐like kinase‐2, zilurgisertib (INCB000928), is under evaluation in fibrodysplasia ossificans progressiva. Cardiac safety was assessed using electrocardiogram (ECG) parameters and a plasma concentration‐heart rate‐corrected QT (C‐QTc) interval analysis of pooled data from single ascending ...
Yan‐ou Yang +5 more
wiley +1 more source