Results 71 to 80 of about 53,179 (222)

Nortriptyline Inhibits Lysosomal Exocytosis‐Mediated SASP During Gastric Cancer Progression via Targeting HOXA1‐PITX2 Phase Separation

open access: yesAdvanced Science, EarlyView.
This study identifies that HOXA1 facilitates transcriptional activity of PITX2 in liquid condensates, resulting in up‐regulation of MCOLN1 and RAB3A followed by lysosomal exocytosis of LGALS1 and IGFBP7 from senescent cells, thus activating AKT signaling and EMT.
Yi Zhou   +10 more
wiley   +1 more source

Resummation of the transverse-energy distribution in Higgs boson production at the Large Hadron Collider [PDF]

open access: yes, 2014
We compute the resummed hadronic transverse-energy ($E_T$) distribution due to initial-state QCD radiation in the production of a Standard Model Higgs boson of mass 126 GeV by gluon fusion at the Large Hadron Collider, with matching to next-to-leading ...
Grazzini, Massimiliano   +3 more
core   +3 more sources

Nitrogen‐Boosted H2O2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

open access: yesAdvanced Science, EarlyView.
PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang   +7 more
wiley   +1 more source

Near‐Infrared Conjugated Macrocyclic BODIPYs for Photothermal Cancer Therapy

open access: yesAngewandte Chemie, EarlyView.
Nucleophilic substitution‐cyclization‐dehydrogenation reactions generate a photosensitizer exhibiting enhanced non‐radiative transitions, resulting in excellent photothermal therapeutic effects. Abstract With this research we developed a cyclization strategy that effectively converts radiative transitions (RTs) to non‐radiative transitions (NRTs ...
Fei Cheng   +5 more
wiley   +2 more sources

Dimensional crossover of thermal conductance in graphene nanoribbons: A first-principles approach

open access: yes, 2012
First-principles density-functional calculations are performed to investigate the thermal transport properties in graphene nanoribbons (GNRs). The dimensional crossover of thermal conductance from one to two dimensions (2D) is clearly demonstrated with ...
Callaway J   +7 more
core   +1 more source

Pushing Biomolecule Detection Limit With Graphene Field‐effect Transistor Biosensors

open access: yesAdvanced Electronic Materials, EarlyView.
Graphene knows your health! This work presents a comprehensive overview of recent advances in graphene field‐effect transistor (GFET) biosensors for ultrasensitive biomolecule detection. How device engineering, high‐mobility graphene synthesis, and tailored surface chemistry push detection limits is highlighted, while discussing emerging strategies ...
Co Dang Pham   +4 more
wiley   +1 more source

Tailored Core‐Shell Nanocarrier for Therapeutic Drug Delivery via Visible Light Activation

open access: yesAngewandte Chemie, EarlyView.
A core‐shell nanocarrier activated by visible light, composed of poly(3‐octylthiophene‐2,5‐diyl) (POT), iron oxide (II, III) (Fe3O4), polyvinyl alcohol (PVA), and trazodone tetraphenylborate (TRZ+ TPB−). During POT photooxidation (POT+), TRZ+ is liberated driven by the maintenance of particle's electroneutrality.
Deric Andrade‐Alarcón   +3 more
wiley   +2 more sources

Atomistic Modeling of Valence Change Memory Devices: What Can We Learn from Simulations?

open access: yesAdvanced Electronic Materials, EarlyView.
Simulation of resistive switching in valence change memory cells tusing density functional theory (DFT), molecular dynamics (MD), nudged elastic band (NEB), kinetic Monte Carlo (KMC), and quantum transport (QT) methods. Abstract Resistive switching devices based on the valence change effect have shown promise for applications in emerging in‐memory and ...
Marko Mladenović, Mathieu Luisier
wiley   +1 more source

Relation between the behaviors of P-wave and QT dispersions in elderly patients with heart failure

open access: yesArquivos Brasileiros de Cardiologia, 2002
OBJECTIVE: To assess the relation between P-wave and QT dispersions in elderly patients with heart failure. METHODS: Forty-seven elderly patients (75.6±6 years) with stable heart failure in NYHA functional classes II or III and with ejection fractions of
Szlejf Cláudia   +9 more
doaj  

Bending instability in galactic discs. Advocacy of the linear theory

open access: yes, 2013
We demonstrate that in N-body simulations of isolated disc galaxies there is numerical vertical heating which slowly increases the vertical velocity dispersion and the disc thickness.
Rodionov, S. A., Sotnikova, N. Ya.
core   +3 more sources

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