Results 91 to 100 of about 182,594 (345)

Major Adverse Cardiac Events with Ondansetron: A Systematic Review

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Evidence base: 170 randomized trials, 23,421 adults, predominantly single‐dose IV ondansetron, mean follow‐up 20 days. Observed outcomes: Major adverse cardiac events were rare, no ventricular arrhythmias or torsades de pointes observed. Conclusion: Ondansetron was not associated with increased mortality or serious cardiac arrhythmias in adult ...
Michael Cristian Garcia   +11 more
wiley   +1 more source

QT Interval and QT Variability

open access: yes, 2012
Sudden cardiac death (SCD) is among the most common types of mortality in developed countries. It for more deaths each year than the total number of deaths from AIDS, breast cancer, lung cancer and stroke together. SCD accounts for approximately 50% of all deaths from cardiovascular diseases and 20% of total mortality (1).
Vrtovec, Bojan, Poglajen, Gregor
openaire   +3 more sources

Short QT interval syndrome

open access: yesКардиоваскулярная терапия и профилактика, 1970
Every year, sudden cardiac death (SCD) takes lives of 400 000 American citizens, and in 10-20% ofthe cases, fatal outcome is explained by hereditary pathology.
I. G. Fomina   +2 more
doaj  

Population Pharmacokinetic and Exposure‐Efficacy Analysis of Baloxavir Marboxil for Influenza Treatment and Post‐Exposure Prophylaxis in Children

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Baloxavir acid (baloxavir), the active metabolite of the prodrug baloxavir marboxil, is a selective inhibitor of the influenza virus cap‐dependent endonuclease. The population pharmacokinetic (popPK) profile of baloxavir in adults/adolescents has been described previously.
Sylvie Retout   +6 more
wiley   +1 more source

The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]

open access: yes, 2012
This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L   +5 more
core   +1 more source

Cardiorespiratory cross‐frequency coupling biomarker for sudden unexpected death in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Sudden unexpected death in epilepsy (SUDEP) often follows generalized tonic–clonic seizures during sleep, likely resulting from impaired brainstem cardiorespiratory function. We used ictal electrocardiogram (ECG)‐based cross‐frequency phase–amplitude coupling (PAC) to detect cardiorespiratory disruptions, comparing SUDEP to non‐SUDEP
Adam C. Gravitis   +7 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Relationship between QT interval and ventricular electrical axis: A new suggestion for Lead selection in QT interval measurement [PDF]

open access: yesActa Medica Iranica, 2000
Exploration of the interlead QT variation (QT dispersion) introduced cardiologists to some new concepts including the deed to define a standard for lead selection in the measurement of QT interval and the reason or factors contributing to QT dispersion ...
"Moradman S, Hatamizadeh P "
doaj   +2 more sources

QT interval prolongation after sertraline overdose: a case report

open access: yesBMC Emergency Medicine, 2005
Background Selective serotonin reuptake inhibitors (SSRIs) are the most common antidepressants used in first-world countries and are generally well tolerated.
Holman Nicole D   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy