Results 251 to 260 of about 180,206 (347)

Risk Factors Associated with Unsuccessful Dofetilide Initiation Due to Excessive QT Interval Prolongation: A Retrospective Study. [PDF]

J Innov Card Rhythm Manag
Rast J, Whitebloom G, Makram OM, Nain P, Seth L, Wayne N, Houlihan P, Warner A, Sohinki D.   +8 more
europepmc   +1 more source

Prospective in silico trials identify combined SK and K2P channel block as an effective strategy for atrial fibrillation cardioversion

The Journal of Physiology, EarlyView.
Abstract figure legend In silico trials were conducted in 654 virtual patients with atrial fibrillation (AF) to assess the cardioversion efficacy of three pharmacological treatments: single SK and K2P channel block and combined SK+K2P channel inhibition. Left: representative virtual AF patient with the atria inside the torso.
Albert Dasí, Lucas Arantes Berg, Hector Martinez‐Navarro, Alfonso Bueno‐Orovio, Blanca Rodriguez   +4 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

A smartphone application for semi-automated QT interval analysis based on a snapshot of an electrocardiogram trace displayed on a patient monitor. [PDF]

J Clin Monit Comput
Beckmann D, Flick M, Kouz K, Saugel B.
europepmc   +1 more source

Frequency of QT Interval Prolongation in ChronicLiver Disease Patients

, 2019
Wali Khan Mashwani, Tahir Ullah Khan
openalex   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

The Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo, Zachary D. Long, Arie O. Verkerk, Jose M. Ferrero, T. Alexander Quinn, Jose F. Rodriguez Matas   +5 more
wiley   +1 more source

Does COVID-19 impact the QT interval prolongation? Answers from genetic causal inference. [PDF]

Biosci Rep
Song Y, Zheng Z.
europepmc   +1 more source

Fetal QT Interval Estimation Using Sequential Hypothesis Testing

, 2017
Suhong Yu, B.D. Van Veen, William J. Lutter, Ronald T. Wakai   +3 more
openalex   +2 more sources

Electrophysiological characterization of pre‐adolescents born with intrauterine growth restriction: insights from clinical and computational data

The Journal of Physiology, EarlyView.
Abstract figure legend Depolarization and repolarization duration analysis was conducted in preadolescent groups with IUGR and controls using a 12‐lead ECG. Principal component analysis was applied over the 12‐lead ECGs to generate spatially transformed leads better suited for robust ECG fiducial points detection.
Freddy L. Bueno‐Palomeque, Ernesto Zacur, Esther Pueyo, Fàtima Crispi, Pablo Laguna, Ana Mincholé   +5 more
wiley   +1 more source