Results 251 to 260 of about 73,159 (323)

Concentration-QT modelling shows no evidence of clinically significant QT interval prolongation with capivasertib at expected therapeutic concentrations. [PDF]

Br J Clin Pharmacol, 2022
Voronova V, Cullberg M, Delff P, Parkinson J, Dota C, Schiavon G, Maroj B, Rekić D, Cheung SYA.   +8 more
europepmc   +1 more source

QT Interval Prolongation in TB/HIV Coinfection: Drug Interactions, Risks, and Clinical Recommendations

Constantin Martiniuc, Serghei Pisarenco, Aliona David, Oxana Plamadeala, Victoria Nicolaev   +4 more
openalex   +2 more sources

Sport‐specific differences in ACL injury, treatment and return to sports: Football

Knee Surgery, Sports Traumatology, Arthroscopy, Volume 33, Issue 11, Page 4050-4058, November 2025.
Abstract The management of anterior cruciate ligament (ACL) ruptures is carried out differently in prevention, treatment and rehabilitation for athletes than for non‐athletes. However, different approaches to managing ACL ruptures are also discussed in different sports.
Werner Krutsch, Dominik Szymski, Johannes Rüther, Volker Musahl, Alberto Grassi, Thomas Tischer, Markus Gesslein   +6 more
wiley   +1 more source

No QT interval prolongation effect of sepiapterin: a concentration-QTc analysis of pooled data from phase 1 and phase 3 studies in healthy volunteers and patients with phenylketonuria. [PDF]

J Pharmacokinet Pharmacodyn
Gao L, Hu Y, Smith N, Uvarov A, Peyret T, Gosselin NH, Kong R.   +6 more
europepmc   +1 more source

Circadian Rhythm: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 11, November 2025.
This review offers a comprehensive overview of the mechanisms by which circadian rhythms modulate tissue homeostasis, alongside the associations between circadian disturbances and circadian rhythm‐related diseases. Furthermore, we offer insights into circadian rhythm‐regulating therapies, which may contribute to the development of novel strategies for ...
Kangkang Zha, Bobin Mi, Yuan Xiong, Shuyan Wu, Li Lu, Shengming Zhang, Xuan Lu, Hei Chung Mak, Jianping Huang, Adriana C. Panayi, Samuel Knoedler, Lili Chen, Guohui Liu, Sien Lin   +13 more
wiley   +1 more source

QT-Interval Prolongation Associated with Supratherapeutic Guanfacine Concentration: A Case Report. [PDF]

J Med Toxicol
Inoue F, Okazaki Y, Kashiwa K, Ichiba T, Namera A.   +4 more
europepmc   +1 more source

The Half RR Rule: A Poor Rule of Thumb and Not a Risk Assessment Tool for QT Interval Prolongation [PDF]

, 2015
Ingrid Berling, Geoffrey K. Isbister
openalex   +1 more source

Drug-induced QT interval prolongation: mechanisms and clinical management

Therapeutic Advances in Drug Safety, 2012
S. Nachimuthu, M. Assar, J. Schussler
semanticscholar   +1 more source

Characteristics and toxicology of adult deaths due to quetiapine toxicity in Australia, 2000–2024

Journal of Forensic Sciences, Volume 70, Issue 6, Page 2434-2441, November 2025.
Abstract Quetiapine is an atypical antipsychotic that has been associated with both intentional and unintentional deaths. We aimed to determine, stratified by intentionality: (1) The characteristics and circumstances of adult deaths attributed solely to quetiapine toxicity in Australia, 2000–2024; (2) The blood toxicology of cases for quetiapine and ...
Shane Darke, Johan Duflou, Julia Lappin, Michael Farrell, Amy Peacock   +4 more
wiley   +1 more source

Case report of QT interval prolongation induced by anamorelin in an obese patient with non-small cell lung cancer. [PDF]

J Pharm Health Care Sci
Yokota H, Asahi R, Akamine Y, Kobayashi M, Wakabayashi H, Sakamoto S, Okuda Y, Sato K, Nakayama K, Kikuchi M.   +9 more
europepmc   +1 more source