Results 11 to 20 of about 143,558 (182)

Drug-induced QT interval prolongation in patients with heart failure with preserved ejection fraction.

PLoS ONE
Heart failure (HF) with reduced ejection fraction (HFrEF) is a risk factor for drug-induced QT interval prolongation. It is unknown if HF with preserved ejection fraction (HFpEF) is also associated with an increased risk.
Chien-Yu Huang, Brian R Overholser, Kevin M Sowinski, Heather A Jaynes, Richard J Kovacs, James E Tisdale   +5 more
doaj   +2 more sources

Evaluation of qt prolongation in patients following conduction system pacing implantation [PDF]

Europace
Mehrdad Golian, Ghaith Almidani, Mohammad Asif, Djalal Fakim, L Ayala Valani, F.A.Y.A.L.A. VALANI, F. Ayala‐Paredes   +6 more
europepmc   +3 more sources

Serial electrocardiogram recordings revealed a high prevalence of QT interval prolongation in patients with tuberculosis receiving fluoroquinolones

Journal of the Formosan Medical Association, 2023
Background: Fluoroquinolones, crucial components of treatment regimens for drug-resistant tuberculosis (TB), are associated with QT interval prolongation and risks of fatal cardiac arrhythmias. However, few studies have explored dynamic changes in the QT
Ke-Shiuan Ju, Ren-Guey Lee, Hsien-Chun Lin, Jin-Hua Chen, Bi-Fang Hsu, Jann-Yuan Wang, Nguyen Van Dong, Ming-Chih Yu, Chih-Hsin Lee   +8 more
doaj   +1 more source

Effect of Clofazimine Concentration on QT Prolongation in Patients Treated for Tuberculosis

Antimicrobial Agents and Chemotherapy, 2021
Clofazimine is classified as a WHO group B drug for the treatment of rifampin-resistant tuberculosis. QT prolongation, which is associated with fatal cardiac arrhythmias, is caused by several antitubercular drugs, including clofazimine, but there are no ...
M. Abdelwahab, R. Court, D. Everitt, A. Diacon, R. Dawson, E. Svensson, G. Maartens, P. Denti   +7 more
semanticscholar   +1 more source

QT Prolongation in Cancer Patients

Frontiers in Cardiovascular Medicine, 2021
Background: QT prolongation and torsades de pointes pose a major concern for cardiologists and oncologists. Although cancer patients are suspected to have prolonged QT intervals, this has not been investigated in a large population.
Peter Y. Kim, L. Masha, A. Olson, C. Iliescu, Kaveh Karimzad, Saamir A Hassan, Nicolas L. Palaskas, J. Durand, Cheuk Leung, J. Lopez-Mattei   +9 more
semanticscholar   +1 more source

Bedaquiline Correlation to QT Interval Prolongation in DR-TB Patients

Jurnal Respirasi, 2022
Introduction: The regimen of drug-resistant tuberculosis (DR-TB) is Bedaquiline. One of the adverse events is QT interval prolongation, which can increase the risk of Torsade de Pointes (TdP) and lead to death. DR-TB patient screening before starting the
Vandu Primadana, Indra Yovi, Dyah Siswanti Estiningsih   +2 more
doaj   +1 more source

Torsade de Pointes/QT Prolongation Associated with Antifungal Triazoles: A Pharmacovigilance Study Based on the U.S. FDA Adverse Event Reporting System（FAERS）

Journal of Pharmacy & Pharmaceutical Sciences, 2022
Purpose: Torsade de pointes (TdP)/QT prolongation is a fatal adverse event (AE) when using antifungal triazoles. We aimed to compare the AE signals of TdP/QT prolongation and onset time among different drugs of this kind comprehensively.
Zicheng Yu, Xiaolan Liao
doaj   +1 more source

CLINICAL SIGNIFICANCE OF DRUGINDUCED INTERVALS QT AND QTC PROLONGATION

Рациональная фармакотерапия в кардиологии, 2015
Interval QT prolongation is a predictor of the life-threatening cardiac arrhythmias — polymorphic ventricular tachycardia (torsade de pointes). Long QT syndrome may be congenital or acquired.
N. V. Furman, S. S. Shmatova
doaj   +3 more sources

Managing drug-induced QT prolongation in clinical practice

Postgraduate medical journal, 2020
Many drug therapies are associated with prolongation of the QT interval. This may increase the risk of Torsades de Pointes (TdP), a potentially life-threatening cardiac arrhythmia.
R. Khatib, Fatima Sabir, Caroline Omari, C. Pepper, M. Tayebjee   +4 more
semanticscholar   +1 more source

Scoping review: QT interval prolongation in regimen containing bedaquiline and delamanid in patients with drug-resistant tuberculosis

International Journal of Mycobacteriology, 2022
Background: A regimen containing bedaquiline–delamanid is recommended in management of drug-resistant tuberculosis (DR TB) to increase a success rate.
Oki Nugraha Putra, Yulistiani Yulistiani, Soedarsono Soedarsono   +2 more
doaj   +1 more source