Results 241 to 250 of about 55,181 (324)

Corrected QT Interval Prolongation during Severe Hypoglycemia without Hypokalemia in Patients with Type 2 Diabetes

, 2013
Jaewon Beom, Jung Min Kim, Eun Joo Chung, Ju Yeong Kim, Seung Yeong Ko, Sang Don Na, Cheol Hwan Kim, Gun Park, Mi Yeon Kang   +8 more
openalex   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Physiological mechanisms underlying enhanced performance with blood flow restriction training: neuromuscular, vascular and metabolic adaptations

The Journal of Physiology, EarlyView.
Abstract figure legend We investigated how 6 weeks of dynamic knee‐extensor interval training with blood flow restriction (BFR‐leg) and without (CTRL‐leg) impacts performance and its mechanisms using non‐invasive methods. Specifically, we used gold‐standard methods to assess neuromuscular function, vascular function using Doppler ultrasound, and near ...
Colin Lavigne, Valentin Mons, Clément Lemineur, Oliver Meste, Georges Lefthériotis, Grégory M. Blain   +5 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies.
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

QT Prolongation Preceding Ventricular Fibrillation After Amiodarone Administration: A Case Report. [PDF]

Cureus
Stojanovic M, Nikolic M, Nedeljkovic I, Gojkovic D.   +3 more
europepmc   +1 more source

Sex-specific IKAS activation in rabbit ventricles with drug-induced QT prolongation

, 2020
Adonis Z. Wu, Mu Chen, Dechun Yin, Thomas H. Everett, Zhenhui Chen, Michael Rubart, James N. Weiss, Zhilin Qu, Peng‐Sheng Chen   +8 more
openalex   +2 more sources

Redefining the Treatment Landscape in Gastroparesis: A Clinical Review of Gastric Peroral Endoscopic Myotomy Outcomes and Therapeutic Integration

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Gastroparesis is a chronic gastric motility disorder marked by delayed gastric emptying in the absence of mechanical obstruction. For patients with symptoms refractory to medical and dietary therapy, Gastric Peroral Endoscopic Myotomy (G‐POEM) has emerged as a minimally invasive, pylorus‐targeted intervention that directly addresses pyloric ...
Kobina Essilfie‐Quaye, Carson Creamer, Mohammad Abuassi, Harsimran Kalsi, Neeka Akhavan, Tony Brar, Yaseen Perbtani   +6 more
wiley   +1 more source

A polygenic risk score for the QT interval is an independent predictor of drug-induced QT prolongation. [PDF]

PLoS One
Simon ST, Lin M, Trinkley KE, Aleong R, Rafaels N, Crooks KR, Reiter MJ, Gignoux CR, Rosenberg MA.   +8 more
europepmc   +1 more source

Pharmacologic Treatment of Kleine–Levin Syndrome: A Case Report and Comprehensive Review of Therapeutic Options

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
A 12‐year‐old girl with Klein‐Levin syndrome showed central hypopneas and REM sleep without atonia on 24‐h polysomnography, which normalized after clarithromycin treatment alongside clinical remission. ABSTRACT Kleine–Levin syndrome (KLS) is a rare disorder with limited literature on treatment options and efficacy, especially in adolescents.
Sarisa Thawongit, Vorasith Siripornpanich, Lunliya Thampratankul   +2 more
wiley   +1 more source

Characteristics, predictors and outcomes of new-onset QT prolongation in sepsis: a multicenter retrospective study. [PDF]

Crit Care
Liu W, Shao R, Zhang S, Jin L, Liu R, Chen P, Hu J, Ma H, Wu B, Liang W, Luo X, Li J, Chen W, Xiong N, He B.   +14 more
europepmc   +1 more source