Results 261 to 270 of about 55,181 (324)

Fast 3D UTE in vivo T1 and T2*$$ {\mathrm{T}}_2^{\ast } $$ mapping of fast relaxing knee tissues at 3 T

Magnetic Resonance in Medicine, Volume 95, Issue 2, Page 693-705, February 2026.
Abstract Purpose UTE MR imaging captures quantitative signals in fast‐relaxing tissues, enabling anatomical visualization and quantitative assessment of T1 and T2*$$ {\mathrm{T}}_2^{\ast } $$ relaxation times. However, the clinical application of quantitative UTE MRI is limited by long acquisition times.
Maik Rothe, Selina Riedel, Anne Slawig, Andreas Deistung, Klaus Bohndorf, Richard Brill, Walter A. Wohlgemuth, Alexander Gussew   +7 more
wiley   +1 more source

Model‐Based Meta‐Analysis of the Relationship Between Pioglitazone and Histological Outcomes in Metabolic Dysfunction‐Associated Steatohepatitis Patients

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Given the high prevalence of the population who have metabolic dysfunction‐associated steatohepatitis (MASH), interest is growing in MASH‐targeted treatments. However, currently, there has been only one regulatory approved drug for MASH (Rezdiffra).
Quyen Thi Tran, Tham Thi Bui, Lien Thi Ngo, Bo Ram Yang, In‐Hwan Baek, Van Hung Nguyen, Kyung Ae Lee, Hwi‐yeol Yun, Jung‐woo Chae, Soyoung Lee, Jae Hyun Kim, Woojin Jung   +11 more
wiley   +1 more source

Managing Drug–Drug Interactions Involving the Non‐Prescription Opioid Loperamide Through Physiologically Based Pharmacokinetic Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Loperamide is a widely used nonprescription peripherally acting opioid indicated for diarrhea. Loperamide undergoes extensive first‐pass metabolism, primarily by cytochrome (CYP) 3A and CYP2C8, with minor contributions from CYP2B6 and CYP2D6, and intestinal efflux by P‐glycoprotein (P‐gp).
Zhu Zhou, Garrett R. Ainslie, Mengyao Li, Jean Dinh, Maciej J. Zamek‐Gliszczynski, Ping Zhao, Mary F. Paine   +6 more
wiley   +1 more source

Temporal Variability of the Electromechanical Window in Long-QT Syndrome and Drug-Induced QT Prolongation: Value for Enhanced Arrhythmia-Risk Assessment

Deissler PM, Rahm A, Berkovitch A, Müller ME, Sikking M, Heymans S, Langenberg B, Moersdorf M, Rieder M, Nimani S, Odening KE, Dichtl W, Sabbag A, Volders PGA, ter Bekke RM.   +14 more
europepmc   +1 more source

Suspected pro‐arrhythmic effects of flecainide and the limitations of in‐hospital short‐duration electrocardiography in detecting ventricular arrhythmia burden in a dog with dilated cardiomyopathy

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 10‐year‐old, female, spayed Pitbull mix presented for evaluation of an arrhythmia. Echocardiography revealed enlargement of all cardiac chambers and decreased left ventricular systolic function. Electrocardiography demonstrated isolated, ventricular premature complexes.
Nathan Mitchell, Tamilselvam Gunasekaran, Robert Sanders, Joanne DeSana   +3 more
wiley   +1 more source

A novel Bayesian approach to assessing the risk of QT prolongation

, 2008
Suraj Anand, Sujit K. Ghosh
openalex   +1 more source

Investigating corrected QT prolongation with hydroxychloroquine use among patients with cutaneous sarcoidosis: A multicenter retrospective study [PDF]

Chinemelum Obijiofor, Michelle Sikora, Lynn Liu, Marleigh J. Stern, Kerry Hena, Daniel R. Mazori, Steven G. Friedman, Soutrik Mandal, Avrom S. Caplan   +8 more
openalex   +1 more source

Sodium glucose co‐transporter 2 inhibitors versus dipeptidyl peptidase‐4 inhibitors and the risk of ventricular arrhythmia among patients with type 2 diabetes: A population‐based cohort study

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 935-945, February 2026.
Abstract Aims To determine whether sodium glucose co‐transporter 2 inhibitors (SGLT2i) use, compared with dipeptidyl peptidase‐4 inhibitors (DPP4i) use, is associated with the risk of ventricular arrhythmias (VA) among patients with type 2 diabetes. Materials and Methods We conducted a population‐based cohort study using a prevalent new‐user design and
Wang‐Choi Tang, Pauline Reynier, Antonios Douros, Oriana H. Y. Yu, Robert W. Platt, Kristian B. Filion   +5 more
wiley   +1 more source