Results 11 to 20 of about 142,044 (357)
R/qtl: high-throughput multiple QTL mapping [PDF]
AbstractMotivation: R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl provides a fully comprehensive range of methods for a wide range of experimental cross types. We recently added multiple QTL mapping (MQM) to R/qtl.
Arends, D.+3 more
openaire +3 more sources
Power and accuracy of QTL detection: simulation studies of one-QTL models [PDF]
Nonparametric selective resampling procedures were used to investigate the effect of several factors on the power of quantative trait loci (QTL) detection, the bias and confidence intervals of their position, effect and heritability. The factors studied were population size, QTL position, heritability of the QTL and marker coverage, i.e., marker ...
Gilles Charmet
openalex +9 more sources
The standard variance components method for mapping quantitative trait loci is derived on the assumption of normality. Unsurprisingly, statistical tests based on this method do not perform so well if this assumption is not satisfied. We use the statistical concept of copulas to relax the assumption of normality and derive a test that can perform well ...
Basrak, B.+4 more
openaire +5 more sources
A powerful global test for spliceQTL effects
Abstract Statistical methods to test for effects of single nucleotide polymorphisms (SNPs) on exon inclusion exist but often rely on testing of associations between multiple exon–SNP pairs, with sometimes subsequent summarization of results at the gene level. Such approaches require heavy multiple testing corrections and detect mostly events with large
Renee X. de Menezes+4 more
wiley +1 more source
The roles of MMP8/MMP10 polymorphisms in ischemic stroke susceptibility
Abstract Background Ischemic stroke (IS), a multifactorial and polygenic disease, is the most common cause of death. This study aimed to determine the roles of MMP8/MMP10 polymorphisms in IS susceptibility in the Chinese Han population. Methods MMP8 rs1940475 and rs3765620, and MMP10 rs17860949 from 700 IS patients and 700 controls were genotyped by ...
Yong Zhao+11 more
wiley +1 more source
Abstract Plants have evolved diverse reproductive allocation strategies and seed traits to aid in dispersal, persistence in the seed bank, and establishment. In particular, seed size, dormancy, and early seedling vigor are thought to be key functional traits with important recruitment and fitness consequences across abiotic stress gradients.
Samsad Razzaque, Thomas E. Juenger
wiley +1 more source
Assessment of Five Chilling Tolerance Traits and GWAS Mapping in Rice Using the USDA Mini-Core Collection [PDF]
Rice (Oryza sativa L.) is often exposed to cool temperatures during spring planting in temperate climates. A better understanding of genetic pathways regulating chilling tolerance will enable breeders to develop varieties with improved tolerance during ...
Boykin, Debbie L.+7 more
core +7 more sources
Exome QTL-seq maps monogenic locus and QTLs in barley [PDF]
QTL-seq, in combination with bulked segregant analysis and next-generation sequencing (NGS), is used to identify loci in small plant genomes, but is technically challenging to perform in species with large genomes, such as barley. A combination of exome sequencing and QTL-seq (exome QTL-seq) was used to map the mono-factorial Mendelian locus black ...
Hiroshi Hisano+4 more
openaire +3 more sources
Cowpea leaf width correlates with above ground biomass across diverse environments
Abstract Cowpea (Vigna unguiculata [L.] Walp.) yields within the dry savannahs of Sub‐Saharan Africa are low. Given the contribution of cowpea to food security in this region, it is essential that high‐yielding varieties are developed to improve crop productivity in a sustainable manner.
Anthony Digrado+8 more
wiley +1 more source
Cocoon weight and shell weight are the key economic traits ultimately determining silk yield. In order to detect the main quantitative trait loci (QTL) associated with the cocoon traits of the mulberry silkworm, Bombyx mori, the parents of larvae that ...
Sivaramakurup SREEKUMAR+4 more
doaj +1 more source