Bayesian Method for Disease QTL Detection and Mapping, using a Case and Control Design and DNA Pooling [PDF]
This paper describes a Bayesian statistical method for determining the genetic basis of a complex genetic trait. The method uses a sample of unrelated individuals classified into two groups, for example cases and controls. Each group is assumed to have been genotyped at a battery of marker loci using a laboratory effort efficient technique called DNA ...
arxiv +1 more source
Towards Transfer Learning for Large-Scale Image Classification Using Annealing-based Quantum Boltzmann Machines [PDF]
Quantum Transfer Learning (QTL) recently gained popularity as a hybrid quantum-classical approach for image classification tasks by efficiently combining the feature extraction capabilities of large Convolutional Neural Networks with the potential benefits of Quantum Machine Learning (QML).
arxiv +1 more source
Prediction of haplotypes for ungenotyped animals and its effect on marker-assisted breeding value estimation [PDF]
Background: In livestock populations, missing genotypes on a large proportion of animals are a major problem to implement the estimation of marker-assisted breeding values using haplotypes.
Calus, M.P.L.+2 more
core +3 more sources
Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage
Abstract Background and purpose Nuclear factor erythroid 2‐related factor 2 (NRF2; encoded by the NFE2L2 gene) has been implicated in outcome following aneurysmal subarachnoid haemorrhage (aSAH) through its activity as a regulator of inflammation, oxidative injury and blood breakdown product clearance.
Ben Gaastra+10 more
wiley +1 more source
Genome-wide association study for charcoal rot resistance in soybean harvested in Kazakhstan
Charcoal rot (CR) caused by the fungal pathogen Macrophomina phaseolina is a devastating disease affecting soybean (Glycine max (L.) Merrill.) worldwide. Identifying the genetic factors associated with resistance to charcoal rot is crucial for developing
A. Zatybekov+6 more
doaj +1 more source
Rice root genetic architecture: Meta-analysis from a drought QTL database [PDF]
During the last 10 years, a large number of quantitative trait loci (QTLs) controlling rice root morphological parameters have been detected in several mapping populations by teams interested in improving drought resistance in rice.
Ahmadi, Nourollah+7 more
core +1 more source
AlphaFold‐Guided Bespoke Gene Editing Enhances Field‐Grown Soybean Oil Contents
An AlphaFold‐guided method is developed to functionally optimize soybean sugar transporters and achieve bespoke gene editing of GmSWEET10a/b to improve oil content in an elite soybean cultivar in multi‐year, multi‐site field trials. The combination of AI‐guided protein design and gene editing may unlock a huge potential to improve the genetic trait de ...
Jie Wang+22 more
wiley +1 more source
Compared with the non‐risk G allele of rs9606, the risk T allele of rs9606 decreases the binding affinity of NUDT21 for LYRM4, triggering 3'UTR shortening that stabilizes LYRM4 mRNA and elevates its expression. Increased LYRM4 expression promoted malignant phenotypes of non‐small cell lung cancer (NSCLC) cells through modulating ferroptosis, supporting
Meng Jin+11 more
wiley +1 more source
The conversion of agricultural waste into added‐value products represents an important parameter in the selection of novel crops for Europe, which can help meet biomass demands without competing with food production or increasing environmental pressure. Given that Lupinus mutabilis has been proposed as a novel source of protein and oil for Europe, this
Agata Gulisano+3 more
wiley +1 more source
A Novel Root-Knot Nematode Resistance QTL on Chromosome Vu01 in Cowpea. [PDF]
The root-knot nematode (RKN) species Meloidogyne incognita and M. javanica cause substantial root system damage and suppress yield of susceptible cowpea cultivars.
Guo, Yi-Ning+7 more
core +2 more sources