Results 121 to 130 of about 173,603 (207)

Adjusting Historical Costs for Inflation with the Use of Standardized Automated Tools

ClinicoEconomics and Outcomes Research
Jason Robert Guertin,1– 3 Naomi Hope Chouinard,1– 3 Amélie Forget,4,5 Lucie Blais4,5 1Centre de recherche du CHU de Québec-Université Laval, Quebec City, Canada; 2Department of Social and Preventive Medicine, Faculty of Medicine, Université Laval, Quebec
Guertin JR, Chouinard NH, Forget A, Blais L   +3 more
doaj  

Ventricular enlargement is associated with early Alzheimer's disease pathophysiology. [PDF]

Brain Commun
Hosseini SA, Aumont E, Rahmouni N, Woo MS, Macedo AC, Hall B, Trudel L, Chan T, Fernandez Arias J, Wang YT, Servaes S, Therriault J, Zheng Y, Socualaya KQ, Bezgin G, Tissot C, Oliva-Lopez D, Hopewell R, Hsiao CH, Saleh C, Stevenson J, Lussier F, Wu L, Chu M, Chawla S, Fonov V, Massarweh G, Iturria-Medina Y, Soucy JP, Rudko DA, Gauthier S, Karikari T, Benedet AL, Ashton NJ, Zetterberg H, Montembeault M, Vitali P, Blennow K, Collins DL, Klostranec J, Pascoal TA, Rosa-Neto P.   +41 more
europepmc   +1 more source

Safety soft sensor development for pilot‐scale ilmenite electric arc furnace using long short‐term memory‐based architecture

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Ilmenite electric arc furnaces (EAFs) are used for smelting titanium‐iron oxide ore at high temperatures generated by electrical arcs to produce titanium slag and pig iron. As these units are pushed to their limits, ensuring safe and reliable operation becomes challenging.
Antony Gareau‐Lajoie, Djogap F. Chrysler J., Daniel Rodrigues, Marie‐Ève Gosselin, Moncef Chioua   +4 more
wiley   +1 more source

Synthesis of (E)‐β‐SF5‐Styrenes via a Heck Reaction of in situ Generated Vinylsulfur Pentafluoride†

Chinese Journal of Chemistry, EarlyView.
A Heck cross‐coupling reaction between aryl(hetero)iodides and in situ generated vinylsulfur pentafluoride is reported. This reaction provides β‐SF5‐styrenes in one‐step as a single (E)‐stereoisomer and tolerates a broad range of functional groups. Comprehensive Summary The synthesis of (E)‐(1‐alken‐1‐yl)pentafluoro‐λ6‐sulfanes, a valuable class of ...
Nicolas DeGrâce, Jean‐François Paquin   +1 more
wiley   +1 more source

On subset least squares estimation and prediction in vector autoregressive models with exogenous variables

Canadian Journal of Statistics, EarlyView.
Abstract We establish the consistency and the asymptotic distribution of the least squares estimators of the coefficients of a subset vector autoregressive process with exogenous variables (VARX). Using a martingale central limit theorem, we derive the asymptotic normal distribution of the estimators. Diagnostic checking is discussed using kernel‐based
Pierre Duchesne, Thanh‐Liem Huynh, Mylène Oscar   +2 more
wiley   +1 more source

A goodness‐of‐fit test for regression models with discrete outcomes

Canadian Journal of Statistics, EarlyView.
Abstract Regression models are often used to analyze discrete outcomes, but classical goodness‐of‐fit tests such as those based on the deviance or Pearson's statistic can be misleading or have little power in this context. To address this issue, we propose a new test, inspired by the work of Czado et al.
Lu Yang, Christian Genest, Johanna G. Nešlehová   +2 more
wiley   +1 more source

Safety, Pharmacokinetics, and Dose Recommendations for Nirmatrelvir/Ritonavir in Individuals with Mild to Moderate COVID‐19 and Severe Renal Impairment

Clinical Pharmacology &Therapeutics, EarlyView.
Patients with severe renal impairment and COVID‐19 are at high risk for severe disease and death. Nirmatrelvir/ritonavir, an antiviral therapy for COVID‐19, is eliminated by renal excretion and can accumulate in patients with severe renal impairment.
Jacqueline Gerhart, Candace R. Bramson, Michelle Goulding, Haihong Shi, Olayide Oladoyinbo, Phylinda L. S. Chan, Sunring Chime, Jennifer Hammond   +7 more
wiley   +1 more source

Patient‐ and Clinician‐Related Factors Associated With the Reduction in Opioid Use Among Adults With Chronic Non‐Cancer Pain: A Systematic Review

Clinical Pharmacology &Therapeutics, EarlyView.
Despite known risks, opioids are widely used for chronic non‐cancer pain (CNCP). Clinical guidelines now recommend deprescribing, but factors predicting success are poorly understood. This systematic review aimed to identify clinician and patient factors associated with attaining successful opioid dose reduction or discontinuation in adults with CNCP ...
Alessandra C. Marcelo, Sarah N. Hilmer, David J. Hunter, Stephanie Mathieson, Riyaas Mohamed, Leo Li, Natalie Fung, Anthony Yue, Manuela L. Ferreira   +8 more
wiley   +1 more source

Embryonic cerebrospinal fluid pressure in fetal mice in utero: External factors pressurize the intraventricular space

Developmental Dynamics, EarlyView.
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa, Reina Muramatsu, Takaki Miyata   +2 more
wiley   +1 more source

Heterozygous Med13l mice recapitulate a developmental growth delay and craniofacial anomalies seen in MED13L syndrome

Developmental Dynamics, EarlyView.
Abstract Background Gene transcription is crucial for embryo and postnatal development and is regulated by the Mediator complex. Mediator is comprised of four submodules, including the kinase submodule (CKM). The CKM consists of MED13, MED12, CDK8, and CCNC.
Anna K. Leinheiser, Timothy T. Nguyen, Kayla M. Henry, Mariela Rosales, Eric Van Otterloo, Chad E. Grueter   +5 more
wiley   +1 more source