Results 61 to 70 of about 7,051 (128)

Desarrollo y caracterización de un nuevo esmalte antideslizante de textura lisa y de fácil limpieza para baldosas de gres porcelánico

open access: yesBoletín de la Sociedad Española de Cerámica y Vidrio, 2016
Dada la problemática que presentan los esmaltes antideslizantes convencionales, los cuales poseen una rugosidad superficial que dificulta la limpieza de la superficie de la pieza, se ha diseñado un esmalte antideslizante de naturaleza vitrocerámica que ...
E. Barrachina Albert   +4 more
doaj   +1 more source

Carbamate‐Directed peri‐CH Alkynylation: Application to the Synthesis of Zethrenes and Pyranthrenes

open access: yesChemistryEurope, Volume 4, Issue 5, May 2026.
The Rh(III)‐catalyzed regioselective alkynylation of 1‐pyrenyl and 1‐naphthyl carbamates with bromoacetylenes enables the selective installation of an alkyne at the peri position of readily accessible amino‐substituted polycyclic aromatic hydrocarbons (PAHs).
Xiaoqing Shao   +4 more
wiley   +1 more source

Quantifying Carboxylate Burial in Synthetic Hydrophobic Pockets in Water

open access: yesChemistryEurope, Volume 4, Issue 5, May 2026.
How “buried” is a buried ion? Double mutant cycles quantify the cost of placing a carboxylate within a deep aromatic calix[4]pyrrole pocket in water. The penalty is only +1.3 to +3.0 kcal·mol−1 because water penetrates through cracks and the portal, creating a wet, high‐dielectric microenvironment.
Esteban A. Valencia   +4 more
wiley   +1 more source

Overcoming Aminoglycoside Enzymatic Resistance: Design of Novel Antibiotics and Inhibitors

open access: yesMolecules, 2018
Resistance to aminoglycoside antibiotics has had a profound impact on clinical practice. Despite their powerful bactericidal activity, aminoglycosides were one of the first groups of antibiotics to meet the challenge of resistance.
Sandra G. Zárate   +5 more
doaj   +1 more source

MGL‐Based Drug Conjugate: A Novel Glycan‐Targeting Strategy for Potential Precision Cancer Therapy

open access: yesChemistryEurope, Volume 4, Issue 5, May 2026.
An engineered macrophage galactose‐type lectin (MGL)‐based conjugate (mMGL‐vcMMAE), incorporating an exposed cysteine for site‐specific drug linkage, preserves stability, binding profile, and affinity of the native MGL carbohydrate recognition domain. It also selectively targets Tn/STn‐expressing cancer cells and shows recognition of colorectal cancer ...
Carlos D. L. Lima   +15 more
wiley   +1 more source

One-pot cross-enyne metathesis (CEYM)–Diels–Alder reaction of gem-difluoropropargylic alkynes

open access: yesBeilstein Journal of Organic Chemistry, 2013
Propargylic difluorides 1 were used as starting substrates in a combination of cross-enyne metathesis and Diels–Alder reactions. Thus, the reaction of 1 with ethylene in the presence of 2nd generation Hoveyda–Grubbs catalyst generates a diene moiety ...
Santos Fustero   +5 more
doaj   +1 more source

Magnetism for the Quantification of Sorption in Porous Materials From Liquid Media

open access: yesChemistry–Methods, Volume 6, Issue 5, May 2026.
This adsorption quantification technique uses external magnetic fields and a magnetic holder to measure mass changes during adsorption, making it universally applicable to any adsorbate. Unlike standard methods, it requires calibration only for the adsorbent rather than for every analyte.
Rubén Pérez‐Aguirre   +2 more
wiley   +1 more source

Monovalent mannose‐glycoconjugates of sulforaphane reprogram human dendritic cells via NFATc1 to induce immune tolerance under inflammatory conditions

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1993-2008, May 2026.
Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez   +6 more
wiley   +1 more source

Synthetic Implications of Spin States in the Reactivity of Ni Intermediate Complexes in Coupling Reactions

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 16, 25 April 2026.
The formation of triplet Ni(II) complexes by activation of bromoalkenes with alkyl‐ or boryl Ni(I) is key to control the outcome of the reductive cross‐coupling of bromoalkanes precluding the formation of alkylboronates. We present a mechanistic study on the Ni‐catalyzed cross‐coupling reaction of bromoalkanes with diboron compounds as reductants.
Diego J. Cárdenas
wiley   +1 more source

Silyl Rearrangements in Gold‐Catalyzed Transformations

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 15, 22 April 2026.
The synergy between the exceptional ability of gold catalysts to activate unsaturated substrates and the inherent tendency of organosilicon reagents to undergo silyl‐group rearrangements has unlocked a range of novel transformations, enabling access to otherwise challenging molecular architectures.
Patricia García‐Martínez   +1 more
wiley   +1 more source

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