Results 1 to 10 of about 107,378 (149)

Ten Years Milestones in Xanthine Oxidase Inhibitors Discovery: Febuxostat-Based Inhibitors Trends, Bifunctional Derivatives, and Automatized Screening Assays

open access: yesOrganics, 2022
Xanthine oxidase (XO) is an enzyme involved in the oxidative process of hypoxanthine and xanthine to uric acid (UA). This process also produces reactive oxygen species (ROS) as byproducts.
Miguel F. S. de Abreu   +4 more
doaj   +1 more source

Inhibitory capacity of extracts and main constituents of hop flowers

open access: yesFuture Journal of Pharmaceutical Sciences, 2023
Background Hops (Humulus lupulus Linn.) produce flowers that are used on an industrial scale to impart sensory properties to beer and have some pharmacologic properties already published in the literature.
Francisco Mateus Gomes do Nascimento   +7 more
doaj   +1 more source

Near-Infrared-Emitting Meso-Substituted Heptamethine Cyanine Dyes: From the Synthesis and Photophysics to Their Use in Bioimaging

open access: yesChemosensors, 2023
Heptamethine cyanine dyes were synthesized in good yields by the reaction between quaternary indoles and a pentamethinic salt, under mild reaction conditions minimizing photooxidation.
Louise Kommers Reimann   +7 more
doaj   +1 more source

2-Nitro-1-vinyl-1H-imidazole

open access: yesMolbank, 2022
Nitroimidazoles are pharmacophoric groups responsible for important antiparasitic activity against several infectious diseases. 2-Nitroimidazoles are found in some antiparasitic drugs and are one of the main moieties responsible for the biological ...
Afonso Santine M. M. Velez   +5 more
doaj   +1 more source

The Neurospora crassa PCL-1 cyclin is a PHO85-1 (PGOV) kinase partner that directs the complex to glycogen metabolism and is involved in calcium metabolism regulation

open access: yesFrontiers in Microbiology, 2022
Cyclins are a family of proteins characterized by possessing a cyclin box domain that mediates binding to cyclin dependent kinases (CDKs) partners. In this study, the search for a partner cyclin of the PHO85-1 CDK retrieved PCL-1 an ortholog of yeast ...
Jonatas Erick Maimoni Campanella   +8 more
doaj   +1 more source

Study Toward the Total Synthesis of Pyrenophorin

open access: yesOrbital: The Electronic Journal of Chemistry, 2012
Macrodiolides are macrocyclic compounds containing two ester groups in a cyclic chain. Of this class of compounds, Pyrenophorin (1) shows antifungal activity, and is produced from the pathogenic fungus Pyrenophora avenae.
Everaldo F. Santos Filho   +3 more
doaj   +1 more source

Flavonóis glicosilados antioxidantes de Nectandra grandiflora (Lauraceae)

open access: yesEclética Química, 2018
The bioassay-guided fractionation of the ethanol extract from Nectandra grandiflora leaves led to the isolation of two flavonol glycosides which inhibited the bleaching of b -carotene on the TLC assay.
Alan Bezerra Ribeiro   +2 more
doaj   +1 more source

Soybean oil transesterification: Study of using Nb2O5.xH2O as catalyst in biodiesel production

open access: yesOrbital: The Electronic Journal of Chemistry, 2012
Economic and environmental reasons show a trend towards replacing fossil fuels with biofuels such as those from triglycerides. Biodiesel can be obtained from vegetable oils and animal fat through several processes such as transesterification ...
Deborah A. dos Santos   +4 more
doaj   +1 more source

2-Chloro-4,6-bis{(E)-3-methoxy-4-[(4-methoxybenzyl)oxy]styryl}pyrimidine: Synthesis, Spectroscopic and Computational Evaluation

open access: yesMolbank, 2021
A novel curcumin analog namely 2-chloro-4,6-bis{(E)-3-methoxy-4-[(4-methoxybenzyl)oxy]-styryl}pyrimidine (compound 7) was synthesized by three-step reaction. The condensation reaction of protected vanillin with 2-chloro-4,6-dimethylpyrimidine (6) was the
Otávio Augusto Chaves   +5 more
doaj   +1 more source

Brazilian contributions to alcohol dehydrogenases-catalyzed reactions throughout the 21st century

open access: yesResults in Chemistry, 2022
Biocatalysis is well-established in (bio)chemical sciences and Brazil has significantly contributed to the growth of this theme. In this context, herein we have compiled the advances in alcohol dehydrogenases-catalyzed biotransformations in the last two ...
Jullyane da Silva de Oliveira Gomes   +4 more
doaj   +1 more source

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