Results 101 to 110 of about 4,449,819 (289)

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Solution and Stability of a Multi-Quadratic Functional Equation

Mathematics
In this paper, we characterize the general solution to a system of functional equations with respect to the multi-quadratic mappings by proving that any such mapping can be uniquely represented via a 2n-additive pairwise symmetric mapping.
Jae-Hyeong Bae, Won-Gil Park
doaj   +1 more source

The Open-Loop Discounted Linear Quadratic Differential Game for Regular Higher Order Index Descriptor Systems [PDF]

In this paper we consider the discounted linear quadratic differential game for descriptor systems that have an index larger than one. We derive both necessary and sufficient conditions for existence of an open-loop Nash (OLN) equilibrium.
Salmah, Y., Wijayanti, I.E., Engwerda, J.C.   +2 more
core  

Overcoming Artificial Structures in Resolution‐Enhanced Hi‐C Data by Signal Decomposition and Multi‐Scale Attention

Advanced Science, EarlyView.
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li, Kelly Yichen Li, Chiara Nicoletti, Stephen Kwok‐Wing Tsui, Pier Lorenzo Puri, Qin Cao, Kevin Y. Yip   +6 more
wiley   +1 more source

Interpretable Machine Learning Framework for Nb─Si Based Alloy Design with Enhanced Fracture Toughness

Advanced Science, EarlyView.
An interpretable machine learning framework integrating SHAP and PDP analysis identifies critical design descriptors from 139 physicochemical features for Nb─Si alloys. The framework achieves <7% prediction error and guides the discovery of Nb38.5Ti38.5Si3Zr18V2 alloy with 22.791 MPa·m1/2 fracture toughness, breaking the 20 MPa·m1/2 barrier.
Dezhi Chen, Chao Xu, Jingyue Yu, Qi Wang, Hongze Fang, Shuo Yin, Turab Lookman, Ruirun Chen   +7 more
wiley   +1 more source

High Tree Species Diversity Promotes Thermal Enhancement Response of Microbial Carbon Use Efficiency

Advanced Science, EarlyView.
ABSTRACT Predicting soil carbon dynamics under warming is constrained by limited understanding of microbial thermal adaptation, particularly whether microbial carbon use efficiency (CUE) can adapt to warming and how plant diversity modulates this response. Using soils from a natural tree species diversity gradient in a subtropical forest, we combined a
Pengpeng Duan, Changqing Ye, Xinyi Yang, Chaoqun Wang, Wolfgang Wanek, Jian‐sheng Ye, Hongzhao Yuan, Hu Du, Kongcao Xiao, Xunyang He, Kelin Wang, Dejun Li   +11 more
wiley   +1 more source

Lipschitz stability of the K-quadratic functional equation

, 2018
Let N be the set of all positive integers, G an Abelian group with a metric d and E a normed space. For any f : G → E we define the k-quadratic difference of the function f by the formula Qk ƒ(x; y) := 2ƒ(x) + 2k2ƒ(y) - f(x + ky) - f(x - ky) for x; y ∈ G
Chahbi, Abdellatif, Kabbaj, Samir, EL-Fassi, Iz-iddine   +2 more
core  

Biomimetic Self‐Reconfigurable Soft Gripper for Cross‐Scale, Multi‐Particle, and High‐Load Multifunctional Manipulation

Advanced Science, EarlyView.
A fully soft, self‐reconfigurable gripper inspired by rapeseed flowers is monolithically 3D‐printed and electronics‐free, switching between diagonal and parallel finger arrangements. Establishing a self‐reconfigurable grasping paradigm, the gripper enables diverse manipulation tasks, including rotating bulbs, picking fruits, grasping cross‐scale ...
Qiping Xu, Bin Wang, Jinxin Chen, Zhengqiang Guo, Baisong Yang, Chaoqian Chen, Jiancheng Cai, Chee‐Meng Chew, Shiju E   +8 more
wiley   +1 more source

The Optimal Linear Quadratic Feedback State Regulator Problem for Index One Descriptor Systems [PDF]

In this note we present both necessary and sufficient conditions for the existence of a linear static state feedback controller if the system is described by an index one descriptor system. A priori no definiteness restrictions are made w.r.t.
Salmah, Y., Wijayanti, I.E., Engwerda, J.C.   +2 more
core  

Plaid‐Like Spin Splitting and Chirality of Magnon Bands in Antiferromagnetic MnTe2

Advanced Science, EarlyView.
Helicity‐ and angle‐resolved Raman spectroscopy reveals chiral magnons in the non‐coplanar antiferromagnet MnTe 2. Combined with first‐principles calculations and spin‐wave theory, the results establish its altermagnetic character through circular Raman dichroism, reduced rotational symmetry, and a distinctive plaid‐like momentum‐space magnon spin ...
Dirk Wulferding, Daehyeon An, Jiwon Choi, Dongmin Moon, Youngsu Choi, Sivasakthi Kuppusamy, Sritharan Krishnamoorthi, Raman Sankar, Myung Joon Han, Se Kwon Kim, Kwang‐Yong Choi   +10 more
wiley   +1 more source