Results 81 to 90 of about 3,071 (219)

First LDLRAP1 and Recurrent LDLR Mutations in Tunisian Families With Familial Hypercholesterolemia

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Familial hypercholesterolemia (FH) is a genetic disorder characterised by elevated plasma LDL‐cholesterol, predisposing to premature atherosclerotic cardiovascular disease. Most cases follow an autosomal dominant pattern (ADH) caused by pathogenic variants in LDLR, APOB or PCSK9.
Wirath Ben Ncir, Afif Ben‐Mahmoud, Hamdi Frikha, Fatma Abdelhedi, Faten Hadj Kacem, Nabila Majdoub, Mouna Mnif, Hyung‐Goo Kim, Leila Ammar Keskes, Jouke‐Jan Hottenga   +9 more
wiley   +1 more source

Aged Zebrafish as a Spontaneous Model of Cardiac Valvular Disease

Aging Cell, Volume 24, Issue 12, December 2025.
Natural ageing in zebrafish results in spontaneous development of valvular degeneration in both the atrioventricular (AV) and bulboventricular (BV) valves. Aged zebrafish valves are larger and exhibit cystic regions, immune cell infiltration, early osteoblast differentiation and increased regurgitation.
Laura Bevan, Jessica Radford, Helena Urquijo, Joseph Carr, Alice Etheridge, Stephen Cross, Melanie Hezzell, Rebecca J. Richardson   +7 more
wiley   +1 more source

A Long‐Term Survivor with Tetralogy of Fallot Treated Only with the Classical Blalock‐Taussig Shunt

Case Reports in Cardiology, Volume 2018, Issue 1, 2018., 2018
The prognosis of tetralogy of Fallot (TOF) treated only with Blalock‐Taussig shunt (BTS) operation is unclear. A woman with TOF underwent classic BTS operation at 10 years of age. Despite no medication, she delivered two children and worked without apparent heart failure. At 72 years of age, she complained of dyspnea on exertion and leg edema.
Yu Yamada, Tomoko Ishizu, Hidekazu Tsuneoka, Yutaka Eki, Hitoshi Horigome, Tayfun Sahin   +5 more
wiley   +1 more source

Single coronary ostium in a patient with quadricuspid aortic valve combined with aneurysmal ascending aortic dilatation

Journal of Cardiothoracic Surgery, 2017
Background The presence of a fourth aortic valve cusp (quadricupsid aortic valve) is a rare congenital malformation and is often accompanied by other anomalies of the adjacent cardiovascular structures.
Do Yeon Kim, Hwan Wook Kim
doaj   +1 more source

Surgical repair of truncal valve regurgitation† [PDF]

, 2017
OBJECTIVES Truncal valve regurgitation remains a short- and long-term risk factor for patients with truncus arteriosus. There are limited data available on techniques and outcomes of truncal valve repair (TVR).
Baird, Christopher W., Bautista-Hernandez, Victor, del Nido, Pedro J., Marx, Gerald R., Mayer, John E., Myers, Patrick O., Pigula, Frank A.   +6 more
core  

Quadricuspid aortic valve in pregnancy: a case discussion [PDF]

A quadricuspid aortic valve (QAV) is an exceptionally rare congenital heart anomaly first time identified in 1862. This condition involves the presence of four cusps in the aortic valve instead of three, leading to potential complication such as aortic ...
Goswami, Neelam, Saidhandapani, Kalyani
core   +2 more sources

Insuficiência Valvar Aórtica por Valva Quadricúspide: uma variação anatômica [PDF]

, 2022
Resumo A valva aórtica quadricúspide (VAQ) é uma anomalia congênita de achado raro, com probabilidade de desenvolver complicações para os pacientes com o decorrer da idade1,3.
Araújo Nascimento, Bruno, Cariolita Japiassu Moraes, Brenda, Juliano, Anna Vitória Ferreira Gonçalves, Neves Vilas Boas Guimarães Isecke, Fernanda, Veiga Moneró, Edgar   +4 more
core   +2 more sources

Aortic, mitral and tricuspid valvular dysplasia in a 7‐month‐old colt

Equine Veterinary Education, Volume 36, Issue 11, Page e288-e294, November 2024.
Summary A 7‐month‐old Warmblood cross colt was presented for the assessment of a laceration of the right hind pastern of 4‐days duration. At presentation, the colt was in poor body condition and had a rough, dull coat. Cardiac auscultation revealed a grade 5/6 pansystolic murmur on the left side and grade 4/6 continuous murmur on the left and right ...
Jillian Bell, Patrick Shearer, Josephine Hale, Kristopher J. Hughes   +3 more
wiley   +1 more source

Quadricuspid aortic valve : a case report and review of the literature [PDF]

, 2020
Quadricuspid aortic valve (QAV) is a rare congenital anomaly that can present as aortic insufficiency later in life. We report a case of aortic regurgitation associated with a QAV, treated by aortic valve replacement.
Capoccia, Massimo, Cereceda-Monteoliva, Nicholas, Mensah, Kwabena, Petrou, Mario, Stenz, Ruediger   +4 more
core   +1 more source

Quadricuspid aortic valve: intraoperative echocardiographic approach [PDF]

, 2021
La válvula aórtica cuadricúspide se considera una malformación cardíaca rara, así como una etiología exótica de insuficiencia aórtica. La detección de esta anomalía cardíaca se puede realizar mediante ecocardiografía transtorácica y/o transesofágica ...
Amaya, Sebastián, Fierro, Dario Andrade, Orozco, Adriana C, Orozco, David M., Rosero-Britton, Byron R.   +4 more
core   +1 more source