Results 51 to 60 of about 24,881 (223)

DNM1 encephalopathy: A new disease of vesicle fission. [PDF]

, 2017
ObjectiveTo evaluate the phenotypic spectrum caused by mutations in dynamin 1 (DNM1), encoding the presynaptic protein DNM1, and to investigate possible genotype-phenotype correlations and predicted functional consequences based on structural modeling ...
Campbell, Colleen A, Cervenka, Mackenzie C, Cilio, Maria R, Cohen, Julie S, Dlugos, Dennis J, Epi4K Consortium, EuroEPINOMICS-RES NLES Working Group, Fatemi, Ali, Helbig, Ingo, Helbig, Katherine L, Hernandez-Hernandez, Laura, Hollingsworth, Georgie, Huether, Robert, Joshi, Charuta N, Kaplan, Richard A, Kirsch, Heidi, Kolbe, Diana L, Lawson, John A, Littlejohn, Rebecca, Lourenço, Charles, Maher, Bridget, McClellan, Rebecca, McLean, Scott D, Muhle, Hiltrud, Møller, Rikke S, Neubauer, Bernd A, Nunes, Mark E, Palmer, Elizabeth, Pena, Sérgio DJ, Pendziwiat, Manuela, Sagawa, Yoshimi, Sarco, Dean P, Scheffer, Ingrid E, Shinde, Deepali N, Sisodiya, Sanjay M, Slavotinek, Anne, Stephani, Ulrich, von Spiczak, Sarah, Yuen, Amy   +38 more
core   +2 more sources

Three‐year outcomes of repeated botulinum neurotoxin A injections to the lower extremities in young children with spastic cerebral palsy in GMFCS levels I to III

Developmental Medicine &Child Neurology, Volume 68, Issue 6, Page 792-799, June 2026.
In this study, we followed a group of children 2 to 6 years old with spastic cerebral palsy functioning in GMFCS levels I–III, over 3 years. Sixty‐five received BoNT‐A and 59 did not. Repeated BoNT‐A injections over 3 years were not associated with improvements in gross motor function or passive ankle dorsiflexion. Daily step counts, favouring the BoNT‐
Darcy Fehlings, Emma Bohn, Lauren Switzer, Charles H. Goldsmith, Unni Narayanan, Peter L. Rosenbaum, F. Virginia Wright, Gary Foster, CP‐BoNT‐A Study Group, Timothy Carey, Mark Mason, Ronit Mesterman   +11 more
wiley   +1 more source

Participation, environment, and quality of life in children with cerebral palsy and physical disabilities

Developmental Medicine &Child Neurology, Volume 68, Issue 6, Page 800-809, June 2026.
Abstract Aim To compare and examine relationships between participation, environmental factors, and quality of life (QoL) in children with cerebral palsy and physical disability (CP/PD) and typically developing children. Method Participants were 59 children (6–12 years; 31 females): 30 with CP/PD (mean age 8 years 7 months, standard deviation 1 year 6 ...
Nava Gelkop, Batya Engel‐Yeger
wiley   +1 more source

A boccia-based adaptive physical education model for supporting gross motor skill development in students with quadriplegia

Edu Sportivo
Background: Students with quadriplegia often encounter significant barriers to participation in physical education due to limited mobility and the lack of structured adaptive learning models.
Arif Rohman Hakim, Agustanico Dwi Muryadi, Karlina Dwijayanti, Slamet Santoso, Sigit Fredi Hartanto   +4 more
doaj   +1 more source

Timing and volume of fluid administration for patients with bleeding [PDF]

, 2003
Original article can be found at: http://www3.interscience.wiley.com Copyright John Wiley & Sons. ‘This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2003, Issue 3.
Bunn, Frances, Kwan, I., Roberts, I.
core   +1 more source

Arteriovenous shunting in quadriplegia [PDF]

Spinal Cord, 1986
Arterio-venous shunting has been demonstrated in the limbs of ten subjects with traumatic quadriplegia, as shown by increased venous oxygen concentration and a Doppler sonogram pattern indicative of continuous forward flow. This phenomenon is similar to that seen in the diabetic neuropathic foot, suggesting that autonomic dysfunction is a major factor ...
F, Van den Hoogen, L A, Brawn, S, Sherriff, N, Watson, J D, Ward   +4 more
openaire   +2 more sources

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, Volume 13, Issue 25, 4 May 2026.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

HeMoFi4Q: Morse Communication Based on Wi-Fi and Head Motion for Quadriplegia With Environmental Robustness

IEEE Access, 2023
Quadriplegics face a communication obstacle as their physical abilities are restricted, leaving them unable to speak or use their limbs, with only their upper neck being mobile.
Marwa R. M. Bastwesy, Hyuckjin Choi, Yutaka Arakawa   +2 more
doaj   +1 more source

A review of the effectiveness of lower limb orthoses used in cerebral palsy [PDF]

, 2009
To produce this review, a systematic literature search was conducted for relevant articles published in the period between the date of the previous ISPO consensus conference report on cerebral palsy (1994) and April 2008.
Bowers, Roy, ISPO (Funder), Ross, Karyn
core  

From Nerves to Vessels: Unmasking Churg‐Strauss Behind Polyneuropathy

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA), formerly Churg‐Strauss vasculitis, is a rare systemic autoimmune disease. Neurological involvement is a significant complication. This report details a case of EGPA with severe, progressive polyneuropathy and atypical serological findings, highlighting diagnostic challenges and the ...
Hiba Antar, Sylvana Balhas, Zeinab El Mawla   +2 more
wiley   +1 more source